2016
Investigation of cone-beam CT image quality trade-off for image-guided radiation therapy
Bian J, Sharp G, Park Y, Ouyang J, Bortfeld T, Fakhri G. Investigation of cone-beam CT image quality trade-off for image-guided radiation therapy. Physics In Medicine And Biology 2016, 61: 3317-3346. PMID: 27032676, DOI: 10.1088/0031-9155/61/9/3317.Peer-Reviewed Original ResearchConceptsImage-guided radiation therapyCone-beam CTFiltered-backprojectionImage quality trade-offConventional filtered-backprojectionShort-scan reconstructionsFiltered-backprojection algorithmFan-beam reconstructionTV-based algorithmIterative reconstruction algorithmCatphan phantomRadiation therapyAngular rangeTotal-variationOptimal exposure levelClinical scannerScanning configurationReconstruction algorithmImaging conditionsCatphanPhantomExposure levelsTherapyConfigurationRange
2013
Clinical Application of In-Room Positron Emission Tomography for In Vivo Treatment Monitoring in Proton Radiation Therapy
Min C, Zhu X, Winey B, Grogg K, Testa M, Fakhri G, Bortfeld T, Paganetti H, Shih H. Clinical Application of In-Room Positron Emission Tomography for In Vivo Treatment Monitoring in Proton Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2013, 86: 183-189. PMID: 23391817, PMCID: PMC3640852, DOI: 10.1016/j.ijrobp.2012.12.010.Peer-Reviewed Original ResearchConceptsIn-room positron emission tomographyProton therapyIn-roomPositron emission tomography scanIn-room PET scannerPassive scattering proton therapyShapes of target volumesPositron emission tomographyMC predictionBeam range uncertaintiesMeasured PET imagesMonte CarloProton radiation therapyLocal elemental compositionBiological washoutScan timeTreatment headTreatment verificationRange uncertaintiesTarget volumePET scan timePET scannerPET systemComputed tomographyMC results