2019
Lysosome‐Targeted Bioprobes for Sequential Cell Tracking from Macroscopic to Microscopic Scales
Park G, Lee J, Levitz A, Fakhri G, Hwang N, Henary M, Choi H. Lysosome‐Targeted Bioprobes for Sequential Cell Tracking from Macroscopic to Microscopic Scales. Advanced Materials 2019, 31: e1806216. PMID: 30740778, PMCID: PMC6574216, DOI: 10.1002/adma.201806216.Peer-Reviewed Original ResearchConceptsMechanism of actionEfficient cellular labellingLive cell trackingCytoplasmic membraneCell trackingOptical propertiesLiving cellsNear-infraredCell-based therapeuticsHost tissuesTrackingCellular analysisLipophilic cationsChemical treatmentCellular effluxLiving organismsTarget cellsCellsCellular retentionExcellent cell permeationTarget tissues
2016
Tissue-Specific Near-Infrared Fluorescence Imaging
Owens E, Henary M, Fakhri G, Choi H. Tissue-Specific Near-Infrared Fluorescence Imaging. Accounts Of Chemical Research 2016, 49: 1731-1740. PMID: 27564418, PMCID: PMC5776714, DOI: 10.1021/acs.accounts.6b00239.Peer-Reviewed Original ResearchConceptsSingle-photon emission computed tomographyPositron emission tomographyVital tissuesReal-time intraoperative navigationReal-time image guidanceContrast agentsTargeted NIR fluorophoresEmission computed tomographyTissue-specific contrast agentsEffective imaging agentsTissue-specific targetingReal-time delineationIntraoperative successTargeted therapyImage guidanceTumor tissuesEPR effectIntraoperative navigationSurgical fieldClinical imaging technologyDiagnostic utilityClinical useEmission tomographySurgical spaceTarget tissues