2020
PET imaging of neurotransmission using direct parametric reconstruction
Petibon Y, Alpert N, Ouyang J, Pizzagalli D, Cusin C, Fava M, Fakhri G, Normandin M. PET imaging of neurotransmission using direct parametric reconstruction. NeuroImage 2020, 221: 117154. PMID: 32679252, PMCID: PMC7800040, DOI: 10.1016/j.neuroimage.2020.117154.Peer-Reviewed Original ResearchConceptsSignal-to-noise ratioImage reconstructionPositron emission tomography image reconstructionLow signal-to-noise ratioPoisson log-likelihood functionScattered coincidencesDetector sensitivityPET sinogramsStatistical fluctuationsEstimate parametric imagesGradient-based optimizationParametric reconstructionLog-likelihood functionEffects of head movementVoxel scalePositron emission tomographySimplified reference region modelActivity concentration data
2010
Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections
Guérin B, Fakhri G. Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections. IEEE Transactions On Medical Imaging 2010, 30: 759-773. PMID: 21118770, PMCID: PMC3120772, DOI: 10.1109/tmi.2010.2095025.Peer-Reviewed Original ResearchConceptsScattered coincidencesEnergy resolutionE-pdfNCAT phantomDependent correctionsEnergy of individual photonsScatter correctionEnergy dependent correctionsEnergy probability density functionScatter correction schemeTotal energy spectrumList-mode acquisitionEnergy informationPositron emission tomography dataActivity distribution estimationScatter sinogramIndividual photonsEnergy spectrumCylindrical phantomEnergy distributionMonte Carlo simulationsScattering approachPhotonsScatteringScattering component
2006
Simultaneous Dual Tracer PET Using Generalized Factor Analysis of Dynamic Sequences
Fakhri G, Sitek A, Guérin B. Simultaneous Dual Tracer PET Using Generalized Factor Analysis of Dynamic Sequences. 2006, 4: 2128-2130. DOI: 10.1109/nssmic.2006.354334.Peer-Reviewed Original Research