2024
Radiomics-driven personalized radiotherapy for primary and recurrent tumors: A general review with a focus on reirradiation
Beddok A, Orlhac F, Rozenblum L, Calugaru V, Créhange G, Dercle L, Nioche C, Thariat J, Marin T, El Fakhri G, Buvat I. Radiomics-driven personalized radiotherapy for primary and recurrent tumors: A general review with a focus on reirradiation. Cancer/Radiothérapie 2024, 28: 597-602. PMID: 39406602, DOI: 10.1016/j.canrad.2024.09.002.Peer-Reviewed Original ResearchPersonalized radiotherapyTumor localizationTreatment planningMedian AUCImaging modalitiesRisk of recurrenceHead and neckImprove treatment precisionPredicting clinical outcomesOptimal treatment planQuantitative imaging biomarkersRecurrent tumorsApplication of radiomicsRecurrent cancerClinical radiotherapyExternal validationClinical outcomesRadiotherapyReirradiationLack of external validationMEDLINE searchTreatment precisionImaging biomarkersImaging protocolTumor
2018
Subject-specific brain tumor growth modelling via an efficient Bayesian inference framework
Chang Y, Sharp G, Li Q, Shih H, El Fakhri G, Ra J, Woo J. Subject-specific brain tumor growth modelling via an efficient Bayesian inference framework. Proceedings Of SPIE--the International Society For Optical Engineering 2018, 10574: 105742i. PMID: 30050231, PMCID: PMC6056378, DOI: 10.1117/12.2293145.Peer-Reviewed Original ResearchTumor growthOptimal treatmentExternal beam radiotherapyBrain tumor progressionBeam radiotherapyBrain tumor growthTumor growth modelTumor infiltrationTumor parametersTumor progressionEffective therapyClinical dataTherapy planningTumorIndividualized therapyTherapyTumor boundariesProliferation rateRadiotherapyNon-invasiveState-of-the-art methodsTreatmentState-of-the-artChemotherapy
2015
Synergistic role of simultaneous PET/MRI-MRS in soft tissue sarcoma metabolism imaging
Zhang X, Chen Y, Lim R, Huang C, Chebib I, Fakhri G. Synergistic role of simultaneous PET/MRI-MRS in soft tissue sarcoma metabolism imaging. Magnetic Resonance Imaging 2015, 34: 276-279. PMID: 26523656, PMCID: PMC4761342, DOI: 10.1016/j.mri.2015.10.027.Peer-Reviewed Original ResearchConceptsSoft tissue sarcomasMagnetic resonance imagingHigh (18)F-FDG uptakeT2 hyperintense massMagnetic resonance spectroscopyNeoadjuvant radiotherapyPathological resultsTumor marginsTissue sarcomasImaging findingsPET/MRI scansPET scansRight thighRadiotherapyNormal tissuesEmission tomographyResonance imagingMetabolite profilesSarcomaPET/MRIChemoRTChemoradiationSynergistic rolePETSurgery