2020
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques
Guehl N, Ramos-Torres K, Linnman C, Moon S, Dhaynaut M, Wilks M, Han P, Ma C, Neelamegam R, Zhou Y, Popko B, Correia J, Reich D, Fakhri G, Herscovitch P, Normandin M, Brugarolas P. Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques. Cerebrovascular And Brain Metabolism Reviews 2020, 41: 1721-1733. PMID: 33090071, PMCID: PMC8221756, DOI: 10.1177/0271678x20963404.Peer-Reviewed Original ResearchConceptsFocal brain injuryMyelin repair therapyContributions of demyelinationDrivers of disabilityImaging demyelinationBrain injuryMeasurements of molecular changesTool's sensitivity to changesLower myelin contentDemyelinating lesionsNeuronal conductionImpaired conductionDemyelinationBrain penetrationGold standardRhesus macaquesInjured areaMultiple sclerosisMolecular changesMyelin sheathNeurological diseasesHigh metabolic stabilityMRI methodsMRIInjury
2015
SVM Based Lung Cancer Diagnosis Using Multiple Image Features in PET/CT
Guo N, Yen R, Fakhri G, Li Q. SVM Based Lung Cancer Diagnosis Using Multiple Image Features in PET/CT. 2015, 1-4. DOI: 10.1109/nssmic.2015.7582234.Peer-Reviewed Original ResearchIntra-tumor heterogeneityLung cancer diagnosisF-FLTCT textureStage malignancyLung cancerStaging of lung cancerCT texture featuresAdvanced stage malignanciesEarly stage malignancyImprove tumor stagingCancer diagnosisImage featuresPET/CT scansPET/CT imagingTumor stageTumor heterogeneityCancer stageDiagnostic accuracyPatient groupClinical valuePET/CTGold standardLung nodulesPET imaging