2016
Validation of Bayesian analysis of compartmental kinetic models in medical imaging
Sitek A, Li Q, Fakhri G, Alpert N. Validation of Bayesian analysis of compartmental kinetic models in medical imaging. Physica Medica 2016, 32: 1252-1258. PMID: 27692754, PMCID: PMC5720163, DOI: 10.1016/j.ejmp.2016.09.010.Peer-Reviewed Original ResearchConceptsAccurate estimation of uncertaintyComputer simulationsMedical imagesPosterior distributionDistributed noiseTime series of imagesClosed-formSeries of imagesData setsKinetic parametersMarkov chain Monte Carlo methodsPosterior distributions of kinetic parametersNon-linear least squares methodAccurate estimationComputerLeast-squares methodKinetic modelEstimation of kinetic parametersF18-fluorodeoxyglucoseBayesian estimationImagesStatistical inferenceMonte Carlo methodEstimates of uncertaintyInformation
2011
A Nonlocal Averaging Technique for Kinetic Parameter Estimation from Dynamic PET Data
Dutta J, Fakhri G, Leahy R, Li Q. A Nonlocal Averaging Technique for Kinetic Parameter Estimation from Dynamic PET Data. 2011, 3562-3566. DOI: 10.1109/nssmic.2011.6153669.Peer-Reviewed Original ResearchNonlocal meansDenoising schemeGaussian filtering techniquePatlak parametric imagesDenoised time seriesDenoising frameworkClustering stepDistributed natureGaussian filterLocal neighborhoodVoxel-wise estimationHigh noise levelsData setsDenoisingFiltering techniqueSchemeDataLow varianceNoise levelTime activity curvesEstimation of kinetic parametersDynamic PET imagesParameter estimationVoxelImages