2017
Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies
Petibon Y, Rakvongthai Y, Fakhri G, Ouyang J. Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies. Physics In Medicine And Biology 2017, 62: 3539-3565. PMID: 28379843, PMCID: PMC5739089, DOI: 10.1088/1361-6560/aa6394.Peer-Reviewed Original ResearchConceptsPET sinogramsSignal-to-noise ratioList-mode PET dataSiemens Biograph mMR scannerList-mode dataMyocardial perfusion imagingNoise realizationsPET myocardial perfusion imagingLow count levelsLeast-squares fitBiograph mMR scannerPET projection dataOriginal list-mode dataMyocardial blood flowCount levelsParametric reconstructionOSEMReconstruction methodIndependent noise realizationsNormal count levelsSinogramDirect reconstructionDynamic sinogramsKinetic modelPoor signal-to-noise ratio
2015
Penalized Direct Estimation of Parametric Images in PET
Kim K, Fakhri G, Li Q. Penalized Direct Estimation of Parametric Images in PET. 2015, 1-4. DOI: 10.1109/nssmic.2015.7582182.Peer-Reviewed Original ResearchAlternating direction methodDirection methodHigh noise varianceIterative reconstruction processKinetic parameter imagesTV regularizationNoise varianceDirect reconstructionPhysiological kinetic parametersDirection estimationReconstruction processNeighboring voxelsCost functionRidge regressionRaw measurementsConventional direct methodComputer simulationsDynamic imagingSplitting methodKinetic parametersImagesBrain phantomAccurate parametric imagesPoisson likelihoodPotential images
2013
Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach
Rakvongthai Y, Ouyang J, Guerin B, Li Q, Alpert N, Fakhri G. Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach. Medical Physics 2013, 40: 102501. PMID: 24089922, PMCID: PMC3779266, DOI: 10.1118/1.4819821.Peer-Reviewed Original Research