2021
A cross-scanner and cross-tracer deep learning method for the recovery of standard-dose imaging quality from low-dose PET
Xue S, Guo R, Bohn K, Matzke J, Viscione M, Alberts I, Meng H, Sun C, Zhang M, Zhang M, Sznitman R, El Fakhri G, Rominger A, Li B, Shi K. A cross-scanner and cross-tracer deep learning method for the recovery of standard-dose imaging quality from low-dose PET. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 49: 1843-1856. PMID: 34950968, PMCID: PMC9015984, DOI: 10.1007/s00259-021-05644-1.Peer-Reviewed Original ResearchConceptsStructural similarity index measurePET imagingGenerative adversarial networkNuclear medicine physiciansArtificial intelligenceLow-dose scansBaseline image qualityDose reductionConditional generative adversarial networkClinical imaging assessmentSimilarity index measureDiversity of clinical practiceDevelopment of AI technologyDeep learning developmentDose acquisitionImaging assessmentMedicine physiciansImage qualityResultsThe improvementPatientsClinical acceptanceClinical practiceClinical settingAdversarial networkLow-dose PETPersonalised, image-guided, noninvasive brain stimulation in gliomas: Rationale, challenges and opportunities
Sprugnoli G, Rossi S, Rotenberg A, Pascual-Leone A, El-Fakhri G, Golby A, Santarnecchi E. Personalised, image-guided, noninvasive brain stimulation in gliomas: Rationale, challenges and opportunities. EBioMedicine 2021, 70: 103514. PMID: 34391090, PMCID: PMC8365310, DOI: 10.1016/j.ebiom.2021.103514.Peer-Reviewed Original ResearchConceptsHigh-grade gliomasNeuronal activityBrain tumorsProximity of tumor cellsSlow tumor growthAggressive human cancersMalignant brain tumorsBrain stimulationTumor mitosisHealthy brain tissuePatient survivalMechanism of actionImage-guidedTumor cellsTumor growthSynaptic activityHuman cancersTumorTherapeutic interventionsClinical settingNoninvasive brain stimulationElectrical stimulationWhole-brain levelPatientsBrain tissue
2013
State of the Art in Cardiac Hybrid Technology: PET/MR
Nappi C, El Fakhri G. State of the Art in Cardiac Hybrid Technology: PET/MR. Current Cardiovascular Imaging Reports 2013, 6: 338-345. PMID: 24073295, PMCID: PMC3780420, DOI: 10.1007/s12410-013-9213-5.Peer-Reviewed Original ResearchMagnetic resonance imagingPositron emission tomographyAbsence of ionizing radiationPositron emission tomography systemLimitations of PET/MRISensitivity of positron emission tomographyRespiratory motionPhotomultiplier tubeClinical cardiac applicationsSoft tissue contrastPET-CTDetection chainPositron emission tomography dataCardiac morphologyCardiac PET/MRIClinical promisePET/MRIEmission tomographySimultaneous PET/MRIImaging modalitiesPET imagingResonance imagingClinical settingDynamic PET imagesTissue contrast
2012
Ready for prime time? Dual tracer PET and SPECT imaging.
Fakhri G. Ready for prime time? Dual tracer PET and SPECT imaging. American Journal Of Nuclear Medicine And Molecular Imaging 2012, 2: 415-7. PMID: 23145358, PMCID: PMC3484417.Peer-Reviewed Original ResearchSingle photon emission computed tomographyDual-isotope single photon emission computed tomographyPositron emission tomographyPhoton emission computed tomographyDual tracer positron emission tomographyEmission computed tomographyPositron emission tomography studiesAreas of brainSPECT/PET imagingOncologic imagingKeV photonsAnimal modelsDown-scatterClinical potentialEmission tomographyPET radiotracersClinical settingAssociated with physical factorsIn vivoAdult population
2010
WE‐D‐201B‐03: Recent Advances in PET Quantitation of Myocardial Blood Flow
Fakhri G. WE‐D‐201B‐03: Recent Advances in PET Quantitation of Myocardial Blood Flow. Medical Physics 2010, 37: 3433-3433. DOI: 10.1118/1.3469414.Peer-Reviewed Original Research