2019
Bulk motion detection and correction using list-mode data for cardiac PET imaging
Sun T, Petibon Y, Han P, Ma C, Kim S, Alpert N, Fakhri G, Ouyang J. Bulk motion detection and correction using list-mode data for cardiac PET imaging. Proceedings Of SPIE--the International Society For Optical Engineering 2019, 11072: 110722f-110722f-5. DOI: 10.1117/12.2534701.Peer-Reviewed Original ResearchList-mode dataCardiac PET imagingPET list-mode dataMotion-corrected imagesLines of responsePET imaging applicationsCardiac PETImage qualityBulk motionCardiac PET studiesMotion correctionPET imagingBrain PETMotion estimationData-driven approachMotion detectionImaging applicationsImage spaceMoving frameStatic reference frameMotion transformationCorrectionCenter positionMotionReference frame
2014
Motion compensation for brain PET imaging using wireless MR active markers in simultaneous PET–MR: Phantom and non-human primate studies
Huang C, Ackerman J, Petibon Y, Normandin M, Brady T, Fakhri G, Ouyang J. Motion compensation for brain PET imaging using wireless MR active markers in simultaneous PET–MR: Phantom and non-human primate studies. NeuroImage 2014, 91: 129-137. PMID: 24418501, PMCID: PMC3965607, DOI: 10.1016/j.neuroimage.2013.12.061.Peer-Reviewed Original ResearchConceptsMotion correctionWireless markersList-mode reconstructionReconstructed PET imagesMotion correction techniqueObserver signal-to-noise ratioSimultaneous PET-MRMotion artifactsPET phantomPET contrastPET reconstructionBrain PET imagingPET imagingPhantomBrain PETPET-MRIndependent noise realizationsAccurate quantitative valuesHead motionNoise realizationsPET dataSignal-to-noise ratioStatic referenceBrain PET scansActivation markers
2008
Sequential and simultaneous dual‐isotope brain SPECT: Comparison with PET for estimation and discrimination tasks in early Parkinson disease
Trott C, Fakhri G. Sequential and simultaneous dual‐isotope brain SPECT: Comparison with PET for estimation and discrimination tasks in early Parkinson disease. Medical Physics 2008, 35: 3343-3353. PMID: 18697558, PMCID: PMC2673561, DOI: 10.1118/1.2940605.Peer-Reviewed Original ResearchConceptsEnergy resolutionTime-of-flight PET scannerRealistic Monte Carlo simulationsAcquisition energy windowSequential SPECTSystem energy resolutionGamma cameraEnergy windowThree-head cameraPET scannerEmission energyMonte Carlo simulationsDual-isotope SPECTSimultaneous SPECTBrain PETTwo-headed cameraCarlo simulationsProdromal disease stagesIdentical physiological conditionsSpatial resolutionDiscrimination taskStriatal sizeActivity concentrationsEarly identification of PDCamera head
2007
Comparison of Brain PET and Sequential and Simultaneous Dual-isotope SPECT for Estimation Tasks in Normal and Parkinson Subjects
Trott C, Fakhri G. Comparison of Brain PET and Sequential and Simultaneous Dual-isotope SPECT for Estimation Tasks in Normal and Parkinson Subjects. 2007, 5: 3616-3620. DOI: 10.1109/nssmic.2007.4436906.Peer-Reviewed Original ResearchDopamine transporterEarly stages of PDDual-isotope SPECTStages of PDSequential SPECTDisease stageSimultaneous dual-isotope studyStriatal sizeBrain functionImprove patient managementEstimation taskDual-isotope studiesBrain PETDopamineClinical symptomsParkinson's diseasePatient managementSPECT imagesSpecific bindingMotor functionSPECTBrainEarly detectionActivity concentrationsIdentical physiological conditions