2023
Fully automated radiosynthesis of [18F]mG4P027 for mGluR4 imaging
Moon S, Fakhri G, Zhang Z, Brownell A, Wang J. Fully automated radiosynthesis of [18F]mG4P027 for mGluR4 imaging. IRADIOLOGY 2023, 1: 120-127. PMID: 37496513, PMCID: PMC10371389, DOI: 10.1002/ird3.25.Peer-Reviewed Original Research
2017
A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [18F]‐THK‐5351
Neelamegam R, Yokell D, Rice P, Furumoto S, Kudo Y, Okamura N, Fakhri G. A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [18F]‐THK‐5351. Journal Of Labelled Compounds And Radiopharmaceuticals 2017, 60: 140-146. PMID: 27859483, DOI: 10.1002/jlcr.3482.Peer-Reviewed Original ResearchConceptsO-THPNucleophilic fluorination reactionsHydrochloric acidFluorination reactionDilute hydrochloric acidSemi-preparative high-performance liquid chromatographyTosylate precursorHigh-performance liquid chromatographyUncorrected radiochemical yieldDimethyl sulfoxideRadiochemical yieldRadiosynthesis moduleMulti-center trialLiquid chromatographyAutomated radiosynthesisRadiosynthesisPositron emission tomography radiopharmaceuticalsPET imaging agentUnited States Pharmacopeia