2014
Numerical Observer for Objective Assessment on Carotid Plaque Using Spectral CT
Lorsakul A, Fakhri G, Ouyang J, Worstell W, Rakvongthai Y, Laine A, Li Q. Numerical Observer for Objective Assessment on Carotid Plaque Using Spectral CT. 2014, 1-4. DOI: 10.1109/nssmic.2014.7430906.Peer-Reviewed Original ResearchMulti-energy CTNumerical observationsCarotid plaquesMatched filterCT systemDigital anthropomorphic phantomHotelling observerDual-energyPlaque featuresImage binConventional CT imagesConventional CT systemsChannelized Hotelling observerAnthropomorphic phantomClassification performanceCT imagesSpectral CTCalcified plaqueClinical classification taskProcessing stepsSimulated imagesPlaqueSuperior performance4D numerical observer for lesion detection in respiratory‐gated PET
Lorsakul A, Li Q, Trott C, Hoog C, Petibon Y, Ouyang J, Laine A, Fakhri G. 4D numerical observer for lesion detection in respiratory‐gated PET. Medical Physics 2014, 41: 102504. PMID: 25281979, PMCID: PMC4281099, DOI: 10.1118/1.4895975.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputer SimulationFluorodeoxyglucose F18HumansImage Interpretation, Computer-AssistedLung DiseasesModels, BiologicalMonte Carlo MethodMotionPhantoms, ImagingPositron-Emission TomographyRadiopharmaceuticalsRegression AnalysisRespiratory-Gated Imaging TechniquesSignal-To-Noise RatioConceptsRespiratory-gated positron emission tomographyMotion-corrected imagesDetection signal-to-noise ratioLesion detection taskNumerical observationsLesion detection performanceSignal-to-noise ratioPositron emission tomography sinogramsSpherical lesionsHotelling observerMotion correction methodPositron emission tomographyGeant4 ApplicationTomographic EmissionChannelized Hotelling observerAnthropomorphic phantomScanner geometryOSEM algorithmMonte Carlo simulationsPET framesImprove lesion detectionLesion detectionSignal-to-noise ratio measurementsActivity distributionConventional 3D approachTowards coronary plaque imaging using simultaneous PET-MR: a simulation study
Petibon Y, Fakhri G, Nezafat R, Johnson N, Brady T, Ouyang J. Towards coronary plaque imaging using simultaneous PET-MR: a simulation study. Physics In Medicine And Biology 2014, 59: 1203-1222. PMID: 24556608, PMCID: PMC4061607, DOI: 10.1088/0031-9155/59/5/1203.Peer-Reviewed Original ResearchMeSH KeywordsComputer SimulationCoronary AngiographyCoronary StenosisHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyModels, CardiovascularMultimodal ImagingPhantoms, ImagingPositron-Emission TomographyReproducibility of ResultsSensitivity and SpecificityConceptsSimultaneous PET-MRChannelized Hotelling observerAttenuation mapMotion correctionPET-MRFluorodeoxyglucose-positron emission tomography imagingRespiratory motion fieldsMotion correction methodCho SNRMotion correction techniqueAnthropomorphic phantomUncorrected reconstructionsRespiratory motionXCAT phantomCoronary plaque imagingMonte Carlo simulationsPET reconstructionXCATActivity distributionCardiac gatingNon-rigid registrationHotelling observerCarlo simulationsPlaque imagingPhantom
2006
Simultaneous Dual Tracer PET Using Generalized Factor Analysis of Dynamic Sequences
Fakhri G, Sitek A, Guérin B. Simultaneous Dual Tracer PET Using Generalized Factor Analysis of Dynamic Sequences. 2006, 4: 2128-2130. DOI: 10.1109/nssmic.2006.354334.Peer-Reviewed Original Research
2003
Quantitative Ga-67 SPECT Imaging
Moore S, Fakhri G, Park I, Kijewski M. Quantitative Ga-67 SPECT Imaging. 2003, 4: 2898-2900. DOI: 10.1109/nssmic.2003.1352489.Peer-Reviewed Original ResearchPb X-raysContaminating photonsPatient scatterUnscattered photonsAnthropomorphic phantomPhotopeak windowNonuniform attenuationCollimator resolutionAttenuation mapGa-67Iterative reconstructionProjection imagesTumor activityPhotonsNoise realizationsGa-67 imagingTumor estimationQuantitative imagingHistopathological stagingLocal backgroundTumor avidityAverage precisionX-rayCollimatorIterative algorithm
2001
Comparative Assessment of Energy-Based Methods of Compensating for Scatter and Lead X-Rays in Ga-67 SPECT Imaging
Moore S, Fakhri G, Maksud P. Comparative Assessment of Energy-Based Methods of Compensating for Scatter and Lead X-Rays in Ga-67 SPECT Imaging. 2001, 4: 2197-2198. DOI: 10.1109/nssmic.2001.1009260.Peer-Reviewed Original ResearchLead X-raysGa-67Energy windowArtificial neural networkGa-67 SPECT imagingSPECT imagesHigh-energy contaminationGa-67 SPECTPoisson noise realizationsActivity estimation taskTumor activity concentrationAnthropomorphic phantomEvaluable tumorsGS methodTumorMean square errorData setsOrgan uptakeProjection imagesLymphoma studiesNeural networkPixel valuesX-raySpherical tumorNoise realizations