2001
Dobutamine-induced augmentation of left ventricular ejection fraction predicts survival of heart failure patients with severe non-ischaemic cardiomyopathy
Ramahi T, Longo M, Cadariu A, Rohlfs K, Slade M, Carolan S, Vallejo E, Wackers F. Dobutamine-induced augmentation of left ventricular ejection fraction predicts survival of heart failure patients with severe non-ischaemic cardiomyopathy. European Heart Journal 2001, 22: 849-856. PMID: 11350094, DOI: 10.1053/euhj.2001.2654.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionTransplant-free survivalEjection fractionHeart failureVentricular end-diastolic volume indexOverall transplant-free survivalPeak exercise oxygen consumptionSevere non-ischaemic cardiomyopathyEnd-diastolic volume indexFunctional classStrongest prognostic variableChronic heart failureHeart failure patientsPrognosis of patientsNon-ischemic cardiomyopathyExercise oxygen consumptionEquilibrium radionuclide ventriculographyVentriculographic variablesExercise capacityFailure patientsPrognostic valueRadionuclide ventriculographyIntravenous infusionDeltaLVEF
1998
Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: implications for technetium-99m-sestamibi imaging.
Wu JC, Yun JJ, Heller EN, Dione DP, DeMan P, Liu YH, Zaret BL, Wackers FJ, Sinusas AJ. Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: implications for technetium-99m-sestamibi imaging. Journal Of Nuclear Medicine 1998, 39: 417-25. PMID: 9529285.Peer-Reviewed Original ResearchConceptsSingle-vessel stenosisMyocardial blood flowDobutamine stressCoronary stenosisTechnetium-99mBlood flowLeft circumflex artery stenosisCircumflex artery stenosisFlow deficitsSingle coronary stenosisCoronary artery diseaseRate-pressure productRegional myocardial blood flowLeft ventricular pressurePeak dobutamine stressOpen-chest dogsNonischemic flowArtery diseaseArtery stenosisPeak dobutamineSestamibi activitySevere stenosisVentricular pressureSestamibi imagingIschemic zone
1993
Impact of regional ventricular function, geometry, and dobutamine stress on quantitative 99mTc-sestamibi defect size.
Sinusas AJ, Shi Q, Vitols PJ, Fetterman RC, Maniawski P, Zaret BL, Wackers FJ. Impact of regional ventricular function, geometry, and dobutamine stress on quantitative 99mTc-sestamibi defect size. Circulation 1993, 88: 2224-2234. PMID: 8222117, DOI: 10.1161/01.cir.88.5.2224.Peer-Reviewed Original ResearchConceptsHours of reperfusionDobutamine stressMyocardial thickeningVentricular geometryDefect magnitudeCoronary artery occlusionLeft ventricular geometryOpen-chest dogsRegional ventricular functionCircumferential profile analysisDefect sizeMIBI defectsArtery occlusionMyocardial salvageVentricular functionVentricular sizePharmacological stressNonviable myocardiumES imagesMyocardial perfusionInfarcted dogsRegional functionReperfusionRisk areasDogs