2014
Predictors of Physical Inactivity in Men and Women With Type 2 Diabetes From the Detection of Ischemia in Asymptomatic Diabetics (DIAD) Study
McCarthy M, Davey J, Wackers F, Chyun D. Predictors of Physical Inactivity in Men and Women With Type 2 Diabetes From the Detection of Ischemia in Asymptomatic Diabetics (DIAD) Study. The Science Of Diabetes Self-Management And Care 2014, 40: 678-687. PMID: 24942531, PMCID: PMC4169341, DOI: 10.1177/0145721714540055.Peer-Reviewed Original ResearchMeSH KeywordsCanadaDiabetes Mellitus, Type 2Diabetic AngiopathiesExerciseFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedMotor ActivityMyocardial IschemiaPeripheral Nervous System DiseasesPredictive Value of TestsPrevalenceProspective StudiesRisk FactorsSedentary BehaviorTime FactorsUnited StatesConceptsAsymptomatic Diabetics (DIAD) studyPhysical inactivityType 2 diabetesDetection of ischemiaDiabetic studyOverweight/obesityPrimary care practicesPhysical activity dataGender-related differencesAsymptomatic patientsAutonomic neuropathySilent ischemiaSecondary data analysisCare practicesType 2Secondary analysisIschemiaDiabetesTime pointsInactivityBaselineWomenMenGender differencesYears
2012
Gender-based divergence of cardiovascular outcomes in asymptomatic patients with type 2 diabetes: Results from the DIAD study
Tandon S, Wackers F, Inzucchi SE, Bansal S, Staib LH, Chyun DA, Davey JA, Young LH. Gender-based divergence of cardiovascular outcomes in asymptomatic patients with type 2 diabetes: Results from the DIAD study. Diabetes And Vascular Disease Research 2012, 9: 124-130. PMID: 22228772, DOI: 10.1177/1479164111431470.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsymptomatic DiseasesCanadaCardiovascular DiseasesDiabetes ComplicationsDiabetes Mellitus, Type 2FemaleHumansIncidenceKaplan-Meier EstimateMaleMass ScreeningMiddle AgedMyocardial Perfusion ImagingPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsSex FactorsTime FactorsUnited StatesConceptsType 2 diabetesMyocardial perfusion imagingCardiovascular outcomesStress myocardial perfusion imagingAsymptomatic Diabetics (DIAD) studyBetter cardiac outcomesHigh-risk womenCoronary artery diseaseHigh-risk menDetection of ischemiaMPI abnormalitiesAsymptomatic patientsAsymptomatic menCardiac eventsCardiac outcomesArtery diseaseAsymptomatic womenAbnormal screeningDiabetic studyPerfusion imagingDIAD studyWomenMenDiabetesOutcomes
2009
Lessons learned from the detection of ischemia in asymptomatic diabetics (DIAD) study
Wackers FJ, Young LH. Lessons learned from the detection of ischemia in asymptomatic diabetics (DIAD) study. Journal Of Nuclear Cardiology 2009, 16: 855-859. PMID: 19685266, DOI: 10.1007/s12350-009-9138-1.Commentaries, Editorials and Letters
2008
Different manifestations of coronary artery disease by stress SPECT myocardial perfusion imaging, coronary calcium scoring, and multislice CT coronary angiography in asymptomatic patients with type 2 diabetes mellitus
Scholte A, Schuijf J, Kharagjitsingh A, Dibbets-Schneider P, Stokkel M, Jukema J, van der Wall E, Bax J, Wackers F. Different manifestations of coronary artery disease by stress SPECT myocardial perfusion imaging, coronary calcium scoring, and multislice CT coronary angiography in asymptomatic patients with type 2 diabetes mellitus. Journal Of Nuclear Cardiology 2008, 15: 503-509. PMID: 18674717, DOI: 10.1016/j.nuclcard.2008.02.015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCalcinosisComorbidityCoronary Artery DiseaseDiabetes Mellitus, Type 2FemaleHumansIncidenceMaleMiddle AgedNetherlandsReproducibility of ResultsRisk AssessmentRisk FactorsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedVentricular Dysfunction, LeftConceptsType 2 diabetes mellitusCoronary artery diseaseMSCT coronary angiographyAsymptomatic patientsCoronary angiographyDiabetes mellitusPositive CAC scoreMyocardial perfusion imagingCAC scoreCoronary atherosclerosisArtery diseaseCAC scoringCalcium scoringPerfusion imagingAbnormal diagnostic test resultsSilent coronary artery diseaseStress single-photon emissionCoronary artery calcium scoringMultislice CT coronary angiographyTomography myocardial perfusion imagingStress SPECT myocardial perfusion imagingSilent coronary atherosclerosisSPECT myocardial perfusion imagingRelative prognostic valueTomographic coronary angiography
2006
Asymptomatic patients with diabetes mellitus should be screened for coronary artery disease
Wackers F. Asymptomatic patients with diabetes mellitus should be screened for coronary artery disease. Journal Of Nuclear Cardiology 2006, 13: 609-615. PMID: 16945739, DOI: 10.1016/j.nuclcard.2006.06.129.Peer-Reviewed Original ResearchThe Association of Psychological Factors, Physical Activity, Neuropathy, and Quality of Life in Type 2 Diabetes
Chyun DA, Melkus GD, Katten DM, Price WJ, Davey JA, Grey N, Heller G, Wackers FJ. The Association of Psychological Factors, Physical Activity, Neuropathy, and Quality of Life in Type 2 Diabetes. Biological Research For Nursing 2006, 7: 279-288. PMID: 16581898, DOI: 10.1177/1099800405285748.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnxietyAttitude to HealthConnecticutCoronary DiseaseCross-Sectional StudiesDepressionDiabetes Mellitus, Type 2Diabetic NeuropathiesFemaleHostilityHumansLinear ModelsMaleMiddle AgedMotor ActivityMultivariate AnalysisQuality of LifeRisk FactorsSocioeconomic FactorsSurveys and QuestionnairesVirginiaConceptsQuality of lifeBody mass indexDepressive symptomsMass indexPhysical inactivityMedical Outcomes Study Short Form-36Diabetes-related microvascular complicationsHigher body mass indexPoor QOLAsymptomatic Diabetics (DIAD) studyCardiac risk factorsDiabetes-related factorsShort Form-36Type 2 diabetesPsychological factorsDetection of ischemiaMicrovascular complicationsForm-36Diabetes QualityFemale sexRisk factorsAncillary studiesDiabetic studyPhysical activityType 2Letter to the Editor
Venkataraman R, Al-Shaer M, Wackers F. Letter to the Editor. Journal Of Nuclear Cardiology 2006, 13: 300. PMID: 16580967, DOI: 10.1016/j.nuclcard.2006.01.009.Peer-Reviewed Original ResearchAdultAgedBlood Flow VelocityBrachial ArteryCoronary Artery DiseaseData Interpretation, StatisticalEndothelium, VascularExercise TestFemaleHumansIncidenceMaleRadionuclide ImagingRadiopharmaceuticalsReproducibility of ResultsRisk AssessmentRisk FactorsSensitivity and SpecificitySeverity of Illness IndexThalliumUltrasonographyTo the editor
Venkataraman R, Al-Shaer M, Wackers F. To the editor. Journal Of Nuclear Cardiology 2006, 13: 300-300. DOI: 10.1007/bf02971255.Peer-Reviewed Original ResearchAdultAgedBlood Flow VelocityBrachial ArteryCoronary Artery DiseaseData Interpretation, StatisticalEndothelium, VascularExercise TestFemaleHumansIncidenceMaleRadionuclide ImagingRadiopharmaceuticalsReproducibility of ResultsRisk AssessmentRisk FactorsSensitivity and SpecificitySeverity of Illness IndexThalliumUltrasonographyScreening of asymptomatic patients with type 2 diabetes mellitus for silent coronary artery disease: Combined use of stress myocardial perfusion imaging and coronary calcium scoring
Scholte A, Bax J, Wackers F. Screening of asymptomatic patients with type 2 diabetes mellitus for silent coronary artery disease: Combined use of stress myocardial perfusion imaging and coronary calcium scoring. Journal Of Nuclear Cardiology 2006, 13: 11-18. PMID: 16464712, DOI: 10.1016/j.nuclcard.2005.11.002.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsCalcinosisComorbidityCoronary Artery DiseaseDiabetes Mellitus, Type 2Diagnosis, Computer-AssistedExercise TestHumansIncidenceMass ScreeningPrognosisRadionuclide ImagingReproducibility of ResultsRisk AssessmentRisk FactorsSensitivity and SpecificitySurvival RateVentricular Dysfunction, LeftConceptsSilent coronary artery diseaseCoronary artery diseaseCoronary calcium scoringType 2 diabetes mellitusMyocardial perfusion imagingArtery diseaseDiabetes mellitusCalcium scoringPerfusion imagingAsymptomatic individualsStress myocardial perfusion imagingRadionuclide myocardial perfusion imagingEarly appropriate treatmentRecent prospective studiesRates of morbidityAsymptomatic patientsCardiovascular complicationsProspective studyOverall prevalenceClinical combinationAppropriate treatmentClinical investigationMellitusClinical importanceDisease
2004
Acute rest myocardial perfusion imaging for chest pain
Kontos M, Wackers F. Acute rest myocardial perfusion imaging for chest pain. Journal Of Nuclear Cardiology 2004, 11: 470-481. PMID: 15295416, DOI: 10.1016/j.nuclcard.2004.05.004.Peer-Reviewed Original Research
2000
An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial
Stowers S, Eisenstein E, Wackers F, Berman D, Blackshear J, Jones A, Szymanski T, Lam L, Simons T, Natale D, Paige K, Wagner G. An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial. Annals Of Emergency Medicine 2000, 35: 17-25. PMID: 28140201, DOI: 10.1016/s0196-0644(00)70100-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedChest PainClinical ProtocolsCoronary AngiographyCost ControlElectrocardiographyEmergency TreatmentExercise TestFemaleHospital CostsHumansLength of StayMaleMedicareMiddle AgedMyocardial InfarctionReproducibility of ResultsRisk FactorsSingle-Blind MethodTomography, Emission-Computed, Single-PhotonUnited StatesConceptsEarly exercise stress testingExercise stress testingLength of stayChest painHospital costsSingle photon emissionCoronary angiographyStress testingDiagnostic strategiesTomography myocardial perfusion imagingCost/charge ratiosAggressive diagnostic strategyNegative scan resultsPositive scan resultsAcute chest painIntermediate-risk patientsAcute coronary syndromeExercise treadmill testingAdverse clinical outcomesShorter median lengthEmergency department patientsAcute myocardial infarctionScan resultsMyocardial perfusion imagingPhoton emission
1999
Risk Stratification Soon After Acute Infarction
Wackers F, Zaret B. Risk Stratification Soon After Acute Infarction. Circulation 1999, 100: 2040-2042. PMID: 10562256, DOI: 10.1161/01.cir.100.20.2040.Peer-Reviewed Original ResearchCan acute rest imaging shorten evaluation in chest pain centers?
Wackers F. Can acute rest imaging shorten evaluation in chest pain centers? Journal Of Nuclear Cardiology 1999, 6: 676-678. PMID: 10608597, DOI: 10.1016/s1071-3581(99)90106-x.Peer-Reviewed Original Research
1993
Impact of regional ventricular function, geometry, and dobutamine stress on quantitative 99mTc-sestamibi defect size.
Sinusas AJ, Shi Q, Vitols PJ, Fetterman RC, Maniawski P, Zaret BL, Wackers FJ. Impact of regional ventricular function, geometry, and dobutamine stress on quantitative 99mTc-sestamibi defect size. Circulation 1993, 88: 2224-2234. PMID: 8222117, DOI: 10.1161/01.cir.88.5.2224.Peer-Reviewed Original ResearchConceptsHours of reperfusionDobutamine stressMyocardial thickeningVentricular geometryDefect magnitudeCoronary artery occlusionLeft ventricular geometryOpen-chest dogsRegional ventricular functionCircumferential profile analysisDefect sizeMIBI defectsArtery occlusionMyocardial salvageVentricular functionVentricular sizePharmacological stressNonviable myocardiumES imagesMyocardial perfusionInfarcted dogsRegional functionReperfusionRisk areasDogsMyocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography
Haronian H, Remetz M, Sinusas A, Baron J, Miller H, Cleman M, Zaret B, Wackers F. Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography. Journal Of The American College Of Cardiology 1993, 22: 1033-1043. PMID: 8409038, DOI: 10.1016/0735-1097(93)90413-u.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplasty, Balloon, CoronaryClinical ProtocolsCollateral CirculationCoronary AngiographyCoronary DiseaseEvaluation Studies as TopicFemaleHumansMaleMiddle AgedMyocardial InfarctionObserver VariationPredictive Value of TestsPrognosisReproducibility of ResultsRisk FactorsSeverity of Illness IndexTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonConceptsMyocardial risk areaCoronary angiographyCoronary angioplastyQuantitative myocardial perfusionMyocardial perfusionMyocardial areaPercutaneous transluminal coronary angioplastyAngiographic risk scoresSmall risk areasTransluminal coronary angioplastyCoronary artery diseaseCoronary artery stenosisInitial myocardial uptakeAngioplasty balloon inflationArtery diseaseLeft anteriorNonperfused areaArtery stenosisCoronary anatomyCoronary arteryBalloon inflationPatient managementMyocardial uptakeRisk scoreAngioplasty