2012
Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic Dysfunction
Jovin IS, Ebisu K, Liu Y, Finta LA, Oprea AD, Brandt CA, Dziura J, Wackers FJ. Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic Dysfunction. Congestive Heart Failure 2012, 19: 130-134. PMID: 23241105, DOI: 10.1111/chf.12013.Peer-Reviewed Original ResearchConceptsLVEF of patientsLeft ventricular ejection fractionLower peak filling ratePeak filling rateEnd-diastolic volumeNormal peak filling ratesEquilibrium radionuclide angiocardiographyVentricular ejection fractionDiastolic dysfunctionAsymptomatic patientsEjection fractionLow left ventricular ejection fractionNormal left ventricular ejection fractionVentricular end-diastolic volumeMild systolic dysfunctionNormal systolic functionEDV indexSystolic dysfunctionSystolic functionRadionuclide angiocardiographyPatientsDysfunctionRepeat scansFilling rateAngiocardiography
1985
195mGold for Assessment of Cardiac Function
Wackers F, Berger H, Hoffer P, Lange R, Zaret B. 195mGold for Assessment of Cardiac Function. Developments In Nuclear Medicine 1985, 197-221. DOI: 10.1007/978-94-009-5022-1_8.Peer-Reviewed Original ResearchCardiac functionFirst-pass studiesGated cardiac blood pool imagingCardiac blood pool imagingInitial clinical experienceReticulo-endothelial systemEquilibrium radionuclide angiocardiographyBlood pool imagingSerial assessmentRadionuclide angiocardiographyClinical experienceClinical useRadionuclide of choiceInteresting clinical applicationsRed cellsTc99Clinical applicationRadiotracerTotal numberHoursAngiocardiographyKidneyDoseMinimal time interval
1983
Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance
Choi B, Berger H, Schwartz P, Alexander J, Wackers F, Gottschalk A, Zaret B. Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance. American Heart Journal 1983, 106: 638-643. PMID: 6613807, DOI: 10.1016/0002-8703(83)90080-7.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionCongestive heart failureLeft ventricular performanceVentricular performanceEjection fractionAbnormal baselineHeart failureDoxorubicin therapyDoxorubicin cardiotoxicityRadionuclide angiocardiographyAbnormal left ventricular ejection fractionFinal left ventricular ejection fractionAntecedent cardiovascular diseaseSerial radionuclide studiesFirst-pass radionuclide angiocardiographyIdentification of patientsUse of doxorubicinSafe discontinuationThoracic radiationVentricular functionCancer patientsCumulative doseCardiovascular diseaseRadionuclide assessmentGold-195m for serial first pass radionuclide angiocardiography during upright exercise in patients with coronary artery disease
Wackers F, Stein R, Pytlik L, Plankey M, Lange R, Hoffer P, Sands M, Zaret B, Berger H. Gold-195m for serial first pass radionuclide angiocardiography during upright exercise in patients with coronary artery disease. Journal Of The American College Of Cardiology 1983, 2: 497-505. PMID: 6875113, DOI: 10.1016/s0735-1097(83)80277-0.Peer-Reviewed Original ResearchConceptsVentricular ejection fractionLeft ventricular ejection fractionCoronary artery diseaseLeft ventricular functionFirst-pass radionuclide angiocardiographyEjection fractionArtery diseaseVentricular functionRadionuclide angiocardiographyVentricular ejection fraction responseThallium-201 myocardial imagingThallium-201 stress scintigraphyLeft ventricular reserveEjection fraction responseSame exercise testThallium-201 myocardial imagesMulticrystal gamma cameraFirst-pass studiesSerial exerciseVentricular reserveGamma cameraLow radiation dosePeak exerciseUpright exerciseStress scintigraphy
1982
Radionuclide angiographic exercise left ventricular performance in chronic aortic regurgitation: Relationship to resting echographic ventricular dimensions and systolic wall stress index
Lewis S, Riba A, Berger H, Davies R, Wackers F, Alexander J, Sands M, Cohen L, Zaret B. Radionuclide angiographic exercise left ventricular performance in chronic aortic regurgitation: Relationship to resting echographic ventricular dimensions and systolic wall stress index. American Heart Journal 1982, 103: 498-504. PMID: 7064791, DOI: 10.1016/0002-8703(82)90336-2.Peer-Reviewed Original ResearchConceptsChronic aortic regurgitationExercise reserveAortic regurgitationRadius/wall thickness ratioEjection fractionRadionuclide angiocardiographyLV dimensionsEchocardiographic LV dimensionsUpright bicycle exerciseFirst-pass radionuclide angiocardiographyM-mode echocardiographyWall stress indexAR patientsSymptomatic patientsBicycle exerciseVentricular dimensionsVentricular performanceExercise responseExercise performancePatientsEnd systoleEnd diastoleAbsolute changeRegurgitationWall thickness ratio
1981
Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries.
Berger HJ, Sands MJ, Davies RA, Wackers FJ, Alexander J, Lachman AS, Williams BW, Zaret BL. Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries. Annals Of Internal Medicine 1981, 94: 186-91. PMID: 7469209, DOI: 10.7326/0003-4819-94-2-186.Peer-Reviewed Original ResearchConceptsNormal coronary arteriesLeft ventricular performanceChest painVentricular performanceCoronary arteryExercise electrocardiogramAbnormal ejection fraction responseMaximal upright bicycle exerciseCoronary arterial spasmUpright bicycle exerciseEjection fraction responseFirst-pass radionuclide angiocardiographyThallium-201 imagingErgonovine testingVentricular dysfunctionArterial spasmBicycle exerciseErgonovine provocationAdditional patientsTreadmill exercisePerfusion defectsRadionuclide angiocardiographyRegional dysfunctionPatientsFraction response
1980
Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot
Reduto L, Berger H, Johnstone D, Hellenbrand W, Wackers F, Whittemore R, Cohen L, Gottschalk A, Zaret B, Pytlik L. Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot. The American Journal Of Cardiology 1980, 45: 1013-1018. PMID: 7369132, DOI: 10.1016/0002-9149(80)90170-8.Peer-Reviewed Original ResearchConceptsVentricular ejection fraction responseRight ventricular ejection fractionRight ventricular performanceVentricular ejection fractionEjection fraction responseRight ventricular hypertrophyEjection fractionPostoperative patientsVentricular hypertrophyVentricular performanceNormal right ventricular ejection fractionFraction responseThallium-201 myocardial imagingAsymptomatic clinical statusRight ventricular uptakeTotal surgical correctionThallium-201 imagingExercise reserveVentricular uptakeConditions of restClinical statusSurgical correctionRadionuclide angiocardiographyRadionuclide assessmentPatients
1979
Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: Validation of the technique and assessment of variability
Wackers F, Berger H, Johnstone D, Goldman L, Reduto L, Langou R, Gottschalk A, Zaret B, Quartararo L, Pytlik L. Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: Validation of the technique and assessment of variability. The American Journal Of Cardiology 1979, 43: 1159-1166. PMID: 443176, DOI: 10.1016/0002-9149(79)90148-6.Peer-Reviewed Original ResearchConceptsEjection fractionAbsolute ejection fractionLeft ventricular ejection fractionCardiac blood pool imagingVentricular ejection fractionFirst-pass radionuclide angiocardiographyBlood pool imagingRadionuclide angiocardiographyContrast angiographyRepeat studyPatientsAbnormal patientsSeparate daysInterobserver variabilitySame dayDifferent daysDaysAngiographyAngiocardiography