T4. FINGER ON THE PULSE: INTEGRATING GENETIC AND WEARABLE DATA TO EXPLORE THE LINK BETWEEN HEART RATE VARIABILITY, ANXIETY, AND ANTIDEPRESSANTS
Friligkou E, Koller D, Pathak G, Miller E, Lampert R, Stein M, Polimanti R. T4. FINGER ON THE PULSE: INTEGRATING GENETIC AND WEARABLE DATA TO EXPLORE THE LINK BETWEEN HEART RATE VARIABILITY, ANXIETY, AND ANTIDEPRESSANTS. European Neuropsychopharmacology 2023, 75: s164. DOI: 10.1016/j.euroneuro.2023.08.294.Peer-Reviewed Original ResearchHeart rate variabilityAverage RR intervalElectronic health recordsPolygenic risk scoresReuptake inhibitorsAntidepressant classesAntidepressant useSelective serotonin reuptake inhibitorsAntidepressant substancesMendelian randomizationRate variabilityRR intervalsCo-existing health conditionsNorepinephrine reuptake inhibitorsSerotonin reuptake inhibitorsAvailable electronic health recordsBackground Anxiety disordersCardiovascular comorbiditiesAntidepressant prescriptionsOne-sample Mendelian randomizationSerotonin antagonistsTricyclic antidepressantsMajor depressionMillion Veteran ProgramObservational nature