2018
Specific Pro-Inflammatory Signaling Pathways are Induced in Patients with Cardiac Sarcoidosis; Potential Prognostic/Therapeutic Applications
Young B, Oatmen K, Freeburg L, Zellars K, Sapp A, Herzog E, Miller E, Spinale F. Specific Pro-Inflammatory Signaling Pathways are Induced in Patients with Cardiac Sarcoidosis; Potential Prognostic/Therapeutic Applications. Journal Of Cardiac Failure 2018, 24: s10. DOI: 10.1016/j.cardfail.2018.07.033.Peer-Reviewed Original ResearchCardiac sarcoidosisCardiac inflammationSarcoid patientsReceptor levelsEpidermal growth factorNormal subjectsSoluble tumor necrosis factor receptor IITumor necrosis factor receptor IIFluorodeoxyglucose positron emission tomographyPro-inflammatory signaling pathwaysAnti-inflammatory regimensMethods Plasma samplesHeart failure therapySoluble receptor levelsSpecific inflammatory pathwaysSpecific therapeutic targetingInflammatory signaling cascadesSpecific therapeutic targetsPositron emission tomographyCytokine receptor profilesCardiac involvementFailure therapyPrognostic valueTreatment regimensInflammatory pathways
2016
The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis
Ahmadian A, Pawar S, Govender P, Berman J, Ruberg FL, Miller EJ. The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis. Journal Of Nuclear Cardiology 2016, 24: 413-424. PMID: 27457527, DOI: 10.1007/s12350-016-0490-7.Peer-Reviewed Original ResearchConceptsFDG PET/CTPET/CTFDG uptakeCardiac sarcoidosisFDG PET/CT studiesPET/CT studiesImmunosuppressive treatmentCardiac inflammationPartial responseComplete resolutionImproved outcomesSUV thresholdImmunosuppressionFDG responseCT studiesPatientsCTSarcoidosisFurther studiesQuantitative changesUptakeResponseInflammationSUVmaxCMV