2012
Synthesis and evaluation of 11β-(4-Substituted phenyl) estradiol analogs: Transition from estrogen receptor agonists to antagonists
Hanson RN, Hua E, Hendricks JA, Labaree D, Hochberg RB. Synthesis and evaluation of 11β-(4-Substituted phenyl) estradiol analogs: Transition from estrogen receptor agonists to antagonists. Bioorganic & Medicinal Chemistry 2012, 20: 3768-3780. PMID: 22608920, PMCID: PMC3581310, DOI: 10.1016/j.bmc.2012.04.041.Peer-Reviewed Original ResearchMeSH KeywordsEstradiolEstrogen Receptor alphaHumansMolecular StructureStereoisomerismStructure-Activity RelationshipConceptsSynthetic strategyNew compoundsERα-LBDPotential drug delivery systemPrevious synthetic studiesSeries of compoundsDrug delivery systemsClass of compoundsSynthetic methodTerminal groupsFacile accessSynthetic studiesDrug conjugationSpecific structural featuresCompetitive ligandCompoundsSteroidal agonistsDelivery systemRepresentative scaffoldsStructural featuresERβ-LBDSubtype selectivityActive groupAnaloguesScaffolds
1997
A direct stereoselective synthesis of 7β-hydroxytestosterone
Labaree D, Hoyte R, Hochberg R. A direct stereoselective synthesis of 7β-hydroxytestosterone. Steroids 1997, 62: 482-486. PMID: 9185296, DOI: 10.1016/s0039-128x(97)00018-4.Peer-Reviewed Original Research