2019
Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy
Latif SR, Nguyen VQ, Peters DC, Soufer A, Henry ML, Grunseich K, Testani J, Hur DJ, Huber S, Mojibian H, Dicks D, Sinusas AJ, Meadows JL, Papoutsidakis N, Jacoby D, Baldassarre LA. Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy. The International Journal Of Cardiovascular Imaging 2019, 35: 1309-1318. PMID: 30790116, DOI: 10.1007/s10554-019-01551-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAtrial Function, LeftAtrial RemodelingCardiomyopathy, HypertrophicContrast MediaFemaleFibrosisHeart AtriaHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMaleMiddle AgedOrganometallic CompoundsPredictive Value of TestsRetrospective StudiesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsLA fibrosisLV-LGEHypertrophic cardiomyopathyLA-LGELV fibrosisLV parametersLV end-diastolic volumeSetting of HCMAldosterone system inhibitionLate gadolinium enhancement (LGE) sequencesLV global strainLeft ventricular massEnd-diastolic volumeLeft atrial fibrosisMaximum wall thicknessFibrosis correlatesRenin-AngiotensinVentricular strainMedication usageAtrial fibrosisLV remodelingVentricular massLV massSystem inhibitionDiastolic volumePrognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2016
T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1
Hu C, Sinusas AJ, Huber S, Thorn S, Stacy MR, Mojibian H, Peters DC. T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1. Journal Of Cardiovascular Magnetic Resonance 2016, 19: 63. PMID: 28821300, PMCID: PMC5563030, DOI: 10.1186/s12968-017-0375-1.Peer-Reviewed Original ResearchAlgorithmsAnimalsCardiomyopathiesComputer SimulationContrast MediaFeasibility StudiesFemaleFibrosisHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedModels, CardiovascularMonte Carlo MethodOrganometallic CompoundsPhantoms, ImagingPredictive Value of TestsReproducibility of ResultsSus scrofaCMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation
Peters DC, Duncan JS, Grunseich K, Marieb MA, Cornfeld D, Sinusas AJ, Chelikani S. CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation. JACC Cardiovascular Imaging 2016, 10: 207-208. PMID: 27085430, PMCID: PMC5600154, DOI: 10.1016/j.jcmg.2016.01.015.Peer-Reviewed Original Research
2013
Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order
Shaw JL, Knowles BR, Goldfarb JW, Manning WJ, Peters DC. Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order. Journal Of Magnetic Resonance Imaging 2013, 40: 119-125. PMID: 24105717, PMCID: PMC5036388, DOI: 10.1002/jmri.24340.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAlgorithmsAtrial FibrillationBody WaterContrast MediaFemaleGadoliniumHeart AtriaHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial StunningPreoperative CarePulmonary VeinsReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedSubtraction TechniqueConceptsWater-fat separationThree‐dimensional late gadolinium‐enhanced mr imaging of the left atrium: A comparison of spiral versus Cartesian k‐space trajectories
Knowles BR, Peters DC, Clough RE, Razavi R, Schaeffter T, Prieto C. Three‐dimensional late gadolinium‐enhanced mr imaging of the left atrium: A comparison of spiral versus Cartesian k‐space trajectories. Journal Of Magnetic Resonance Imaging 2013, 39: 211-216. PMID: 24006356, DOI: 10.1002/jmri.24146.Peer-Reviewed Original ResearchAortic injury is common following pulmonary vein isolation
Tung P, Hong SN, Chan RH, Peters DC, Hauser TH, Manning WJ, Josephson ME. Aortic injury is common following pulmonary vein isolation. Heart Rhythm 2013, 10: 653-658. PMID: 23318348, DOI: 10.1016/j.hrthm.2013.01.012.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationVein isolationAortic blood poolPercent of patientsNumber of patientsCardiac magnetic resonanceLate gadolinium enhancementSignificant increaseAortic injuryEsophageal injuryAortic enhancementMediastinal structuresGadolinium enhancementPatientsControl groupAortaClinical implicationsHyperenhancementMean signal intensityBlood poolLGELatter groupLA enhancementInjuryLarger LAEvaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge
Karim R, Housden RJ, Balasubramaniam M, Chen Z, Perry D, Uddin A, Al-Beyatti Y, Palkhi E, Acheampong P, Obom S, Hennemuth A, Lu Y, Bai W, Shi W, Gao Y, Peitgen HO, Radau P, Razavi R, Tannenbaum A, Rueckert D, Cates J, Schaeffter T, Peters D, MacLeod R, Rhode K. Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge. Journal Of Cardiovascular Magnetic Resonance 2013, 15: 105. PMID: 24359544, PMCID: PMC3878126, DOI: 10.1186/1532-429x-15-105.Peer-Reviewed Original ResearchConceptsRadio-frequency catheter ablationAtrial fibrillationTreatment of AFEnhancement cardiovascular magnetic resonance imagingLate gadolinium enhancement cardiovascular magnetic resonanceReference standardEnhancement cardiovascular magnetic resonanceCardiovascular magnetic resonance imagingPost-ablation imagesRegions of fibrosisAssessment of treatmentCardiovascular magnetic resonanceMagnetic resonance imagingPost-ablation imagingLA fibrosisCatheter ablationLGE CMR imagesCMR imagesLeft atriumTreatment stratificationScar tissueResonance imagingFibrosisStandardised evaluationKing's College London
2012
Respiratory bellows‐gated late gadolinium enhancement of the left atrium
Peters DC, Shaw JL, Knowles BR, Moghari MH, Manning WJ. Respiratory bellows‐gated late gadolinium enhancement of the left atrium. Journal Of Magnetic Resonance Imaging 2012, 38: 1210-1214. PMID: 23197465, PMCID: PMC3812253, DOI: 10.1002/jmri.23954.Peer-Reviewed Original ResearchConceptsRight inferior pulmonary veinLate gadolinium enhancementRight superior PVAtrial fibrillationGadolinium enhancementRespiratory compensationScar presenceInferior pulmonary veinNav gatingPresence of scarAtrial imagingSuperior PVBlinded gradingPulmonary veinsLeft atriumTrue scarsPatientsQuadrantScarImproved assessmentFibrillationAtrium
2011
Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement
Moghari MH, Peters DC, Smink J, Goepfert L, Kissinger KV, Goddu B, Hauser TH, Josephson ME, Manning WJ, Nezafat R. Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement. Magnetic Resonance In Medicine 2011, 66: 180-186. PMID: 21360738, PMCID: PMC3120912, DOI: 10.1002/mrm.22769.Peer-Reviewed Original Research
2009
Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance
Taclas JE, Nezafat R, Wylie JV, Josephson ME, Hsing J, Manning WJ, Peters DC. Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance. Heart Rhythm 2009, 7: 489-496. PMID: 20122877, PMCID: PMC2843771, DOI: 10.1016/j.hrthm.2009.12.007.Peer-Reviewed Original ResearchRecurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study
Peters DC, Wylie JV, Hauser TH, Nezafat R, Han Y, Woo JJ, Taclas J, Kissinger KV, Goddu B, Josephson ME, Manning WJ. Recurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study. JACC Cardiovascular Imaging 2009, 2: 308-316. PMID: 19356576, PMCID: PMC2703450, DOI: 10.1016/j.jcmg.2008.10.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCatheter AblationCicatrixContrast MediaFemaleGadolinium DTPAHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPredictive Value of TestsProportional Hazards ModelsPulmonary VeinsRecurrenceRisk AssessmentTime FactorsTreatment FailureConceptsRight inferior pulmonary veinCardiac magnetic resonanceLGE cardiac magnetic resonanceRF ablation proceduresPulmonary veinsAF recurrenceAblation proceduresPV isolationLate gadolinium enhancement (LGE) CMRAtrial fibrillation correlatesBidirectional conduction blockAtrial fibrillation patientsInferior pulmonary veinExtent of scarringRadiofrequency ablation lesionsExtent of scarA Pilot StudyFirst yearRecurrent AFThirteen patientsFibrillation patientsParoxysmal AFPV ostiaProcedural successAtrial scarring
2008
Evaluating the left atrium by magnetic resonance imaging
Hauser TH, Peters DC, Wylie JV, Manning WJ. Evaluating the left atrium by magnetic resonance imaging. EP Europace 2008, 10: iii22-iii27. PMID: 18955395, PMCID: PMC2573030, DOI: 10.1093/europace/eun223.Peer-Reviewed Original ResearchConceptsLeft atriumPulmonary veinsRecurrent atrial fibrillationAtrial fibrillation ablationMagnetic resonance imagingFibrillation ablationAtrial fibrillationVariant anatomyAblation therapyMagnetic resonance imaging methodResonance imagingAtriumVeinAnatomyCatheterFibrillationImaging methodTherapyPreventionLeft atrial function and scar after catheter ablation of atrial fibrillation
Wylie JV, Peters DC, Essebag V, Manning WJ, Josephson ME, Hauser TH. Left atrial function and scar after catheter ablation of atrial fibrillation. Heart Rhythm 2008, 5: 656-662. PMID: 18452866, DOI: 10.1016/j.hrthm.2008.02.008.Peer-Reviewed Original ResearchConceptsAtrial systolic functionLA ejection fractionAtrial fibrillationCatheter ablationEjection fractionRadiofrequency ablationLeft atriumAF ablationSystolic functionLA functionCircumferential pulmonary vein isolationMaximum RA volumeRA ejection fractionCardiovascular magnetic resonance imagingPulmonary vein isolationLA scarPersistent atrial fibrillationMaximum LA volumeCine CMR imagingScar volumeMagnetic resonance imagingThromboembolic riskAtrial functionVein isolationConsecutive patients
2007
Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience
Peters DC, Wylie JV, Hauser TH, Kissinger KV, Botnar RM, Essebag V, Josephson ME, Manning WJ. Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience. Radiology 2007, 243: 690-5. PMID: 17517928, DOI: 10.1148/radiol.2433060417.Peer-Reviewed Original ResearchConceptsPulmonary veinsLeft atriumEnhancement MR imagingLeft inferior pulmonary veinMR imagingInferior pulmonary veinEnhancement magnetic resonance imagingLocal institutional review boardUnpaired t-testMagnetic resonance imagingInstitutional review boardIsolation therapyCatheter ablationAtrial fibrillationRadiofrequency ablationInteratrial septumAtrial wallEnhancement patternPatientsInitial experienceAtrial scarResonance imagingRF ablationMR imaging methodsInformed consent