2024
Accelerated 3D metabolite T1 mapping of the brain using variable‐flip‐angle SPICE
Zhao Y, Li Y, Guo R, Jin W, Sutton B, Ma C, Fakhri G, Li Y, Luo J, Liang Z. Accelerated 3D metabolite T1 mapping of the brain using variable‐flip‐angle SPICE. Magnetic Resonance In Medicine 2024, 92: 1310-1322. PMID: 38923032, DOI: 10.1002/mrm.30200.Peer-Reviewed Original ResearchConceptsLow-rank tensor modelGeneralized series modelMetabolite TExperimental resultsBrain metabolitesClinically acceptable scan timeEfficient encodingPhantom experimental resultsAcceptable scan timeNoisy dataSparse samplingImaging problemsData processingHealthy subject dataVariable flip angleFlip angleTensor modelSaturation effectsQuantitative metabolic imagingMRSI techniquePhantomScan timeData acquisitionMetabolic imagingT1 mapping
2023
B1 inhomogeneity‐corrected T1 mapping and quantitative magnetization transfer imaging via simultaneously estimating Bloch‐Siegert shift and magnetization transfer effects
Jang A, Han P, Ma C, Fakhri G, Wang N, Samsonov A, Liu F. B1 inhomogeneity‐corrected T1 mapping and quantitative magnetization transfer imaging via simultaneously estimating Bloch‐Siegert shift and magnetization transfer effects. Magnetic Resonance In Medicine 2023, 90: 1859-1873. PMID: 37427533, PMCID: PMC10528411, DOI: 10.1002/mrm.29778.Peer-Reviewed Original ResearchConceptsBloch-Siegert shiftBloch-SiegertMagnetization transfer effectsMonte Carlo simulationsSpin-lattice relaxationSpin-bath modelMagnetization transferBinary spin-bath modelCarlo simulationsProton fractionOff-resonance irradiationIn vivo brain studiesBloch simulationsPhantom experimentsMagnetizationEstimationTransmitted fieldQuantitative magnetization transferMethod performanceMT effectSignal equation
2021
Free‐breathing 3D cardiac T1 mapping with transmit B1 correction at 3T
Han P, Marin T, Djebra Y, Landes V, Zhuo Y, Fakhri G, Ma C. Free‐breathing 3D cardiac T1 mapping with transmit B1 correction at 3T. Magnetic Resonance In Medicine 2021, 87: 1832-1845. PMID: 34812547, PMCID: PMC8810588, DOI: 10.1002/mrm.29097.Peer-Reviewed Original ResearchMeSH KeywordsHeartHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingReproducibility of ResultsConceptsFlip-angle estimationCardiac T<sub>1</sub> mappingGradient echo readoutThrough-plane spatial resolutionImaging timePractical imaging timesFree breathingPhantom studyB1 correctionAccelerated imagingIn-planeT)-spaceMyocardial T<sub>1</sub> valuesSubspace-based methodsSpatial resolutionImaging experimentsAcquisition schemeT)-space dataSubject-specific timeCorrectionModified Look-Locker inversion recoveryLook-Locker inversion recoveryTime of data acquisitionAverage imaging timeInversion-recovery sequence
2020
Accelerated J‐resolved 1H‐MRSI with limited and sparse sampling of (‐space
Tang L, Zhao Y, Li Y, Guo R, Clifford B, Fakhri G, Ma C, Liang Z, Luo J. Accelerated J‐resolved 1H‐MRSI with limited and sparse sampling of (‐space. Magnetic Resonance In Medicine 2020, 85: 30-41. PMID: 32726510, PMCID: PMC7992196, DOI: 10.1002/mrm.28413.Peer-Reviewed Original ResearchMR‐based PET attenuation correction using a combined ultrashort echo time/multi‐echo Dixon acquisition
Han P, Horng D, Gong K, Petibon Y, Kim K, Li Q, Johnson K, Fakhri G, Ouyang J, Ma C. MR‐based PET attenuation correction using a combined ultrashort echo time/multi‐echo Dixon acquisition. Medical Physics 2020, 47: 3064-3077. PMID: 32279317, PMCID: PMC7375929, DOI: 10.1002/mp.14180.Peer-Reviewed Original ResearchConceptsLinear attenuation coefficientPositron emission tomography attenuation correctionPhysical compartmental modelAttenuation correctionShort T<sub>2</sub> componentPET attenuation correctionRadial k-space trajectoryMagnetic resonance (MR)-based methodK-space trajectoriesRadial trajectoryK-spaceAttenuation coefficientDixon acquisitionsPositron emission tomographyWhole white matterMuting methodImage reconstructionImaging speedMR signalMRAC methodPositron emission tomography imagingCorrectionGray matter regionsPhantomMatter regions
2019
Body motion detection and correction in cardiac PET: Phantom and human studies
Sun T, Petibon Y, Han P, Ma C, Kim S, Alpert N, Fakhri G, Ouyang J. Body motion detection and correction in cardiac PET: Phantom and human studies. Medical Physics 2019, 46: 4898-4906. PMID: 31508827, PMCID: PMC6842053, DOI: 10.1002/mp.13815.Peer-Reviewed Original ResearchMeSH KeywordsArtifactsFluorodeoxyglucose F18HeartHumansImage Processing, Computer-AssistedMovementPhantoms, ImagingPositron-Emission TomographyConceptsList-mode dataMotion-compensated image reconstructionMotion correctionCenter of massPET list-mode dataMotion correction methodMotion detectionMotion estimationImage reconstructionPatient body motionDegrade image qualityNonrigid registrationImage qualityMotion transformationCoincident distributionBody motion detectionCardiac positron emission tomographyBack-projection techniqueCovariance matrixImage volumesBody motionPositron emission tomographyBack-projectionReference framePhantom
2018
SERIAL transmit – parallel receive (STxPRx) MR imaging produces acceptable proton image uniformity without compromising field of view or SAR guidelines for human neuroimaging at 9.4 Tesla
Thulborn K, Ma C, Sun C, Atkinson I, Claiborne T, Umathum R, Wright S, Liang Z. SERIAL transmit – parallel receive (STxPRx) MR imaging produces acceptable proton image uniformity without compromising field of view or SAR guidelines for human neuroimaging at 9.4 Tesla. Journal Of Magnetic Resonance 2018, 293: 145-153. PMID: 30012280, PMCID: PMC6084804, DOI: 10.1016/j.jmr.2018.05.009.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrainElectromagnetic FieldsHeadHumansMagnetic Resonance ImagingNeuroimagingPhantoms, ImagingProtonsSignal-To-Noise RatioConceptsProton MR imagesMR images of human brainArrays of surface coilsImages of human brainSurface coil arrayHuman brain imagingImage uniformityField of viewExcitation profilesSAR guidelinesBirdcage coilFLASH pulse sequenceSensitivity correctionSodium MR imagingPulse sequenceAcceptable uniformityCoil arrayExcitationSignal-to-noiseProtonHigh-resolution imagesSurface coilParallel receiverCoilMR imaging
2017
A minimum-phase Shinnar-Le Roux spectral-spatial excitation RF pulse for simultaneous water and lipid suppression in 1H-MRSI of body extremities
Han P, Ma C, Deng K, Hu S, Jee K, Ying K, Chen Y, Fakhri G. A minimum-phase Shinnar-Le Roux spectral-spatial excitation RF pulse for simultaneous water and lipid suppression in 1H-MRSI of body extremities. Magnetic Resonance Imaging 2017, 45: 18-25. PMID: 28917812, PMCID: PMC5709164, DOI: 10.1016/j.mri.2017.09.008.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsHumansImage Processing, Computer-AssistedLegLipidsMagnetic Resonance SpectroscopyMuscle, SkeletalPhantoms, ImagingProtonsWaterHigh‐resolution dynamic 31P‐MRSI using a low‐rank tensor model
Ma C, Clifford B, Liu Y, Gu Y, Lam F, Yu X, Liang Z. High‐resolution dynamic 31P‐MRSI using a low‐rank tensor model. Magnetic Resonance In Medicine 2017, 78: 419-428. PMID: 28556373, PMCID: PMC5562044, DOI: 10.1002/mrm.26762.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingReproducibility of ResultsConceptsLow-rank tensorImage reconstructionHigh-resolution image reconstructionImage functionSubspace structureData acquisitionFrame-ratePursuit approachCorrelation of dataSubspaceK-space coverageK-spaceImagesSNRMathematical structureReconstructionHigh-resolutionModeling purposesIn vivo studiesMethodTensor
2016
High‐resolution 1H‐MRSI of the brain using short‐TE SPICE
Ma C, Lam F, Ning Q, Johnson C, Liang Z. High‐resolution 1H‐MRSI of the brain using short‐TE SPICE. Magnetic Resonance In Medicine 2016, 77: 467-479. PMID: 26841000, PMCID: PMC5493212, DOI: 10.1002/mrm.26130.Peer-Reviewed Original ResearchConceptsSignal-to-noise ratioHigh-resolution spectroscopic imagingSpatiospectral correlationSpectroscopic imagingIn-plane resolutionSubspace-based techniquesAccelerated data acquisitionSignal processing algorithmsMetabolite signalsIn-planeProcessing algorithmsNuisance signalsLipid signalingBaseline signalDatasetData acquisitionProperties of water
2014
Design of multidimensional Shinnar–Le Roux radiofrequency pulses
Ma C, Liang Z. Design of multidimensional Shinnar–Le Roux radiofrequency pulses. Magnetic Resonance In Medicine 2014, 73: 633-645. PMID: 24578212, PMCID: PMC4147023, DOI: 10.1002/mrm.25179.Peer-Reviewed Original ResearchImproved Image Reconstruction for Subspace-Based Spectroscopic Imaging Using Non-Quadratic Regularization
Wu Z, Lam F, Ma C, Liang Z. Improved Image Reconstruction for Subspace-Based Spectroscopic Imaging Using Non-Quadratic Regularization. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2014, 2014: 2432-2435. PMID: 25570481, DOI: 10.1109/embc.2014.6944113.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputer SimulationImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyPhantoms, ImagingSignal-To-Noise RatioConceptsImage reconstructionLow-rank modelNon-quadratic regularizationHigh-resolution metabolic imagingSparsely sampled datasetsCapabilities of SPICESPICE frameworkOptimization problemPrimal-dualNon-quadraticImagesSNRAlgorithmDatasetPhantom studySparsenessSpectroscopic imaging methodReconstructionSpectroscopic imagingOptimizationRegularizationMethodCapability
2012
Reduced field‐of‐view excitation using second‐order gradients and spatial‐spectral radiofrequency pulses
Ma C, Xu D, King K, Liang Z. Reduced field‐of‐view excitation using second‐order gradients and spatial‐spectral radiofrequency pulses. Magnetic Resonance In Medicine 2012, 69: 503-508. PMID: 22489022, PMCID: PMC3406253, DOI: 10.1002/mrm.24259.Peer-Reviewed Original ResearchConceptsRF pulsesRF pulse lengthSpatially selective radiofrequencyReduced field-of-view imagingBloch equation simulationsField-of-view imagingPulse lengthRadiofrequency pulsesPhantom experimentsSelective radiofrequencyEquation simulationsPulseSecond-order gradientsNonlinear gradientsExcitation accuracyRegion-of-interestSpatial selectivityBlochSpatial dependencePhantom
2010
Joint design of spoke trajectories and RF pulses for parallel excitation
Ma C, Xu D, King K, Liang Z. Joint design of spoke trajectories and RF pulses for parallel excitation. Magnetic Resonance In Medicine 2010, 65: 973-985. PMID: 21413061, DOI: 10.1002/mrm.22676.Peer-Reviewed Original ResearchConceptsJoint design problemExcitation errorsTransmitting sensitivityJoint designCost function evaluationsExcitation systemDesign problemRF pulse designSelection problemMultidimensional RF pulsesExperimental resultsComputational efficiencyRF pulsesPulse designThin slice selectionEquation simulationsBloch equation simulationsSequential selectionConventional methodsSpoke locationExcitation patternsK-spacePulseFunction evaluationsLength limit