2025
Cancer genetics evaluation among individuals at risk for Lynch syndrome across all qualifying indications.
Singh V, Chen G, Sena A, Rafter T, Xicola R, Sharbatji M, Liu J, Brown Q, Brierley K, Healy C, Hughes M, Kashyap N, Llor X. Cancer genetics evaluation among individuals at risk for Lynch syndrome across all qualifying indications. Journal Of Clinical Oncology 2025, 43: 10616-10616. DOI: 10.1200/jco.2025.43.16_suppl.10616.Peer-Reviewed Original ResearchLynch syndromeInherited cancer syndromeFamily historyPersonal historyCancer syndromesFamily history of colorectal cancerColorectal cancerPersonal history of cancerFamily history of cancerYale New Haven Health SystemLS-related cancersGenetic testingLS-associated cancersCancer genetic evaluationAt-riskIdentification of at-risk individualsAt-risk individualsPathogenic variantsLS cancersComparison of categorical variablesIndividuals at-riskEO-CRCPearson chi-squareHealth systemDescriptive statistics
2024
Longer Colonoscopy Withdrawal Time Is Associated With the Detection of Visible Dysplasia in Patients With Inflammatory Bowel Disease
McMillan C, Li D, Mohamed G, Alsadoun D, Almohsen L, Gaidos J, Proctor D, Al-Bawardy B. Longer Colonoscopy Withdrawal Time Is Associated With the Detection of Visible Dysplasia in Patients With Inflammatory Bowel Disease. Crohn's & Colitis 360 2024, 6: otae020. PMID: 38585555, PMCID: PMC10998460, DOI: 10.1093/crocol/otae020.Peer-Reviewed Original ResearchColonoscopy withdrawal timeHigh-definition white light colonoscopyInflammatory bowel diseaseWhite light colonoscopyVisible dysplasiaBowel diseasePersonal historyWithdrawal timeAssociated with detectionEndoscopic healingAdenoma detectionDysplasia detectionDysplasia groupRetrospective studyAdult patientsInvisible dysplasiaColonoscopyPrimary outcomeDysplasiaMultivariate analysisPatientsIncreasing ageGeneral populationMinutesDiseasePrevalence and predictors of aspirin/NSAID use among patients with Lynch syndrome (LS).
Singhal S, Chertok Y, Osorio N, Chavez J, Riggs E, Daly M, Hall M. Prevalence and predictors of aspirin/NSAID use among patients with Lynch syndrome (LS). Journal Of Clinical Oncology 2024, 42: 19-19. DOI: 10.1200/jco.2024.42.3_suppl.19.Peer-Reviewed Original ResearchLynch syndromeAssociated with CPCP useLS patientsPatient advocacy websitesPatient-level factorsPersonal historyColonoscopy surveillanceCP benefitColorectal CAHereditary cancerPatients' perceptionsLifetime riskAdvocacy websitesMarital statusCP usersImpact uptakePrevention benefitsLS participantsPerceptions of CPE-surveyCancer CenterPrevention modalitiesNon-usersPerceived inconveniencePerceptions of cancer prevention options for Lynch syndrome (LS) in a multi-national convenience sample.
Hall M, Singhal S, Osorio N, Chavez J, Riggs E, Chertock Y, Daly M. Perceptions of cancer prevention options for Lynch syndrome (LS) in a multi-national convenience sample. Journal Of Clinical Oncology 2024, 42: 77-77. DOI: 10.1200/jco.2024.42.3_suppl.77.Peer-Reviewed Original ResearchLynch syndromeCancer prevention optionsCA riskNon-usersOne-time surveySupport groupsConvenience sampleCA preventionStratified analysisFox Chase Cancer CenterNegative public attitudesPrevention optionsColonoscopyMSI-H tumorsCA-PTPerceptions of efficacyCancer CenterSide-effect riskPersonal historyBelief statementsSide effect concernsInternational patientsSide effectsMSI-HRiskA Survey of Patient Experience During Molecular Breast Imaging
Hruska C, Gray L, Jenkins S, Block E, Hunt K, Conners A, Zingula S, O'Connor M, Rhodes D. A Survey of Patient Experience During Molecular Breast Imaging. Journal Of Nuclear Medicine Technology 2024, 52: jnmt.123.266856. PMID: 38839120, PMCID: PMC11149590, DOI: 10.2967/jnmt.123.266856.Peer-Reviewed Original ResearchPatient experiencePersonal history of breast cancerDense breastsSurvey of patient experienceHistory of breast cancerPositive patient experienceAssociated with respondents' ageImprove patient experienceSoliciting patient feedbackPatient comfort levelMammographically dense breastsPatient feedbackStudy consentMolecular breast imagingNeck discomfortRespondents' agePersonal historyMammographyComfort levelSource of discomfortBreast compressionBreast cancerEvaluating patientsInfluence willingnessRespondents
2023
Family and personal history of cancer in the All of Us research program for precision medicine
Bruce L, Paul P, Kim K, Kim J, Keegan T, Hiatt R, Ohno-Machado L, Investigators O. Family and personal history of cancer in the All of Us research program for precision medicine. PLOS ONE 2023, 18: e0288496. PMID: 37459328, PMCID: PMC10351738, DOI: 10.1371/journal.pone.0288496.Peer-Reviewed Original ResearchWomen with pathogenic variants in moderate penetrance breast cancer genes: How frequently do they meet high penetrance genetic testing criteria?
Casasanta N, Soper E, Abul-Husn N. Women with pathogenic variants in moderate penetrance breast cancer genes: How frequently do they meet high penetrance genetic testing criteria? Journal Of Clinical Oncology 2023, 41: 10584-10584. DOI: 10.1200/jco.2023.41.16_suppl.10584.Peer-Reviewed Original ResearchGenetic testing criteriaNational Comprehensive Cancer Network criteriaNational Comprehensive Cancer NetworkBreast cancer genesClinical genetic testingGenetic testingPersonal historyPenetrance breast cancer genesBreast cancerPersonal history of breast cancerMP geneGenetic riskModerate penetranceBreast cancer predisposition genesCancer genetic testingCancer genesElectronic medical record reviewHigh-penetrance genesPathogenic variantsMedical record reviewGermline pathogenic variantsCancer predisposition genesAssociated with germline pathogenic variantsManagement of individualsComprehensive Cancer Network
2022
Understanding public perception of bra size
Malphrus E, Desai A, Weiss E, Couto J, Broach R, Butler P. Understanding public perception of bra size. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 4197-4201. PMID: 36180339, DOI: 10.1016/j.bjps.2022.08.038.Peer-Reviewed Original ResearchConceptsBreast cup sizeCup sizeGeneral population sampleSurvey respondentsBreast surgeryPostoperative resultsPreoperative discussionGeneral populationPatientsBra sizeBreastPersonal historyDemographic questionnairePopulation samplePreoperative imagesPatient's breastSurgeonsWomenUse QuestionnaireQuestionnaireFemale respondentsRespondentsSurgery
2021
Polygenic risk for major depression is associated with lifetime suicide attempt in US soldiers independent of personal and parental history of major depression
Stein MB, Jain S, Campbell‐Sills L, Ware EB, Choi KW, He F, Ge T, Gelernter J, Smoller JW, Kessler RC, Ursano RJ. Polygenic risk for major depression is associated with lifetime suicide attempt in US soldiers independent of personal and parental history of major depression. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2021, 186: 469-475. PMID: 34288400, PMCID: PMC8692314, DOI: 10.1002/ajmg.b.32868.Peer-Reviewed Original ResearchConceptsMajor depressive disorderLifetime suicide attemptsParental historySuicide attemptsMajor depressionMDD-PRSMultivariable modelLifetime historyMajor public health problemIncident suicide attemptsPolygenic riskPublic health problemUS Army soldiersRisk stratificationDepressive disorderPolygenic risk scoresRisk scoreSecond cohortHealth problemsCommon genetic variantsFirst cohortPersonal historyCohortGenetic variantsArmy soldiers
2020
Physician Self-disclosure of Lived Experience Improves Mental Health Attitudes Among Medical Students: A Randomized Study
Martin A, Chilton J, Gothelf D, Amsalem D. Physician Self-disclosure of Lived Experience Improves Mental Health Attitudes Among Medical Students: A Randomized Study. Journal Of Medical Education And Curricular Development 2020, 7: 2382120519889352. PMID: 32363235, PMCID: PMC7180952, DOI: 10.1177/2382120519889352.Peer-Reviewed Original ResearchHealth-seeking behaviourMental illnessMental healthMental health needsMedical students' mental healthMental health attitudesMental health issuesMedical studentsRandomized studyHigh riskHealth attitudesControl groupSuicide completionHealth needsSuicidal ideationLate groupEarly groupPhysiciansHealth issuesSuch exposureATP-30Student mental healthPersonal historyIllnessAMI scores
2016
Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015.
Daly M, Pilarski R, Axilbund J, Berry M, Buys S, Crawford B, Farmer M, Friedman S, Garber J, Khan S, Klein C, Kohlmann W, Kurian A, Litton J, Madlensky L, Marcom P, Merajver S, Offit K, Pal T, Rana H, Reiser G, Robson M, Shannon K, Swisher E, Voian N, Weitzel J, Whelan A, Wick M, Wiesner G, Dwyer M, Kumar R, Darlow S. Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015. Journal Of The National Comprehensive Cancer Network 2016, 14: 153-62. PMID: 26850485, DOI: 10.6004/jnccn.2016.0018.Peer-Reviewed Original ResearchConceptsGenetic/Familial High-Risk AssessmentHigh-risk assessmentOvarian cancer risk reductionGenetic testing criteriaNCCN Guidelines InsightsCancer risk reductionRisk of breastHereditary cancer syndromesCommon genetic mutationsOvarian cancer histologiesNCCN guidelinesMultigene testingPancreatic cancerOvarian cancerCancer histologyCancer syndromesGenetic testingBreastPanel meetingGenetic mutationsPersonal historySyndromeRisk reductionCancerManagement recommendations
2012
The effect of family history on adherence to breast cancer screening guidelines.
Hibler L, Chagpar A. The effect of family history on adherence to breast cancer screening guidelines. Journal Of Clinical Oncology 2012, 30: 1571-1571. DOI: 10.1200/jco.2012.30.15_suppl.1571.Peer-Reviewed Original ResearchNational Health Interview SurveyMale breast cancerFemale breast cancerBreast cancerFamily historyBreast cancer screening guidelinesCancer screening guidelinesUse of mammographyHealth Interview SurveyPast yearIndependent predictorsScreening guidelinesNHIS dataUS populationMultivariate analysisCancerDisease controlInterview SurveyWomenAdherenceHigher likelihoodMammographyPersonal historyAgeGuidelines
2006
The incidence of BRCA1 and BRCA2 variants of unknown significance varies in different ethnic populations
Opatt D, Morrow M, Daly M. The incidence of BRCA1 and BRCA2 variants of unknown significance varies in different ethnic populations. Journal Of Clinical Oncology 2006, 24: 10002-10002. DOI: 10.1200/jco.2006.24.18_suppl.10002.Peer-Reviewed Original ResearchHistory of breast cancerGenetic testingAfrican American womenBreast cancerPersonal history of breast cancerGenetic counselingAfrican AmericansBRCA2 sequence alterationsIncidence of BRCA1Fox Chase Cancer CenterMutations of BRCA1Personal history of cancerWhite womenAmerican womenHistory of cancerAfrican American ethnicityPersonal historyClassification of VUSBRCA2 mutationsOvarian cancerBRCA2 variantsClinical dataInvasive breastBRCA2Increased riskFull-Body Skin Examinations and the Female Veteran: Prevalence and Perspective
Federman DG, Kravetz JD, Haskell SG, Ma F, Kirsner RS. Full-Body Skin Examinations and the Female Veteran: Prevalence and Perspective. JAMA Dermatology 2006, 142: 312-316. PMID: 16549706, DOI: 10.1001/archderm.142.3.312.Peer-Reviewed Original ResearchConceptsFull-body skin examinationPrimary care providersCare providersFemale veteransSkin cancerSkin examinationRisk factorsPrimary health care clinicsVeterans Affairs Medical CenterPatient risk factorsHealth care clinicsPercent of subjectsCare clinicsClinic appointmentsCutaneous malignanciesLower incidencePatient reportsMedical CenterCancer altersScreening testPatientsCancerConvenience sampleVeteransPersonal history
2004
Supported socialization for people with psychiatric disabilities: Lessons from a randomized controlled trial
Davidson L, Shahar G, Stayner D, Chinman M, Rakfeldt J, Tebes J. Supported socialization for people with psychiatric disabilities: Lessons from a randomized controlled trial. Journal Of Community Psychology 2004, 32: 453-477. DOI: 10.1002/jcop.20013.Peer-Reviewed Original ResearchFull-Body Skin Examinations: The Patient's Perspective
Federman DG, Kravetz JD, Tobin DG, Ma F, Kirsner RS. Full-Body Skin Examinations: The Patient's Perspective. JAMA Dermatology 2004, 140: 530-534. PMID: 15148096, DOI: 10.1001/archderm.140.5.530.Peer-Reviewed Original ResearchConceptsPrimary care practitionersSkin cancerRisk factorsWest Haven Veterans Affairs Medical CenterVeterans Affairs Medical CenterPatient risk factorsPercent of participantsPatient questionnaireClinic appointmentsCutaneous malignanciesDermatology clinicExamination ratePrimary careLower incidencePatient reportsMedical CenterPatient's perspectiveCare practitionersCancer altersPatientsScreening testCancerConvenience samplePersonal historyLower rates
2003
Follow-up care of breast cancer survivors
Partridge AH, Winer EP, Burstein HJ. Follow-up care of breast cancer survivors. Seminars In Oncology 2003, 30: 817-825. PMID: 14663782, DOI: 10.1053/j.seminoncol.2003.08.026.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsBreast cancerCancer survivorsPossible long-term complicationsSecond primary breast cancerComplications of therapyPrimary breast cancerLong-term complicationsLocal-regional recurrenceSymptoms of recurrenceBreast cancer treatmentPatient-clinician relationshipMetastatic diseaseContralateral breastPsychosocial concernsPsychosocial supportAdequate surveillanceCancer treatmentCancerComplicationsPatientsPersonal historyRecurrenceTherapySurvivorsAttitudes, knowledge, risk perceptions and decision‐making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses
Bluman LG, Rimer BK, Sterba K, Lancaster J, Clark S, Borstelmann N, Iglehart JD, Winer EP. Attitudes, knowledge, risk perceptions and decision‐making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses. Psycho-Oncology 2003, 12: 410-427. PMID: 12833555, DOI: 10.1002/pon.653.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedATP Binding Cassette Transporter, Subfamily G, Member 2ATP-Binding Cassette TransportersBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsDecision MakingDNA Mutational AnalysisFemaleGenetic Predisposition to DiseaseGenetic TestingHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalOvarian NeoplasmsRiskSpousesConceptsGenetic testingBreast cancer susceptibilityOvarian cancerBreast cancerCancer susceptibilityInvolvement of spousesWives' breast cancerBRCA2 mutationsBRCA2 testingFuture interventionsCancerWomenPersonal historyBRCA2Cancer geneticsOne-thirdBRCA1BreastSpousesInvolvementMost spousesDecision-making processTestingSusceptibilityMutations
1998
Overestimation of Hereditary Breast Cancer Risk
Iglehart J, Miron A, Rimer B, Winer E, Berry D, Shildkraut J. Overestimation of Hereditary Breast Cancer Risk. Annals Of Surgery 1998, 228: 375-384. PMID: 9742920, PMCID: PMC1191495, DOI: 10.1097/00000658-199809000-00010.Peer-Reviewed Original ResearchConceptsOvarian cancerHereditary factorsBRCA2 mutationsHereditary breast cancer riskIntensive clinical servicesTest-negative womenExpert panelBreast cancer riskCarrier probabilitiesAffected womenFamily historyCancer riskHereditary riskCancerClinical servicesBreastWomenHigher risk perceptionPretest educationWomen's perceptionsPersonal historyRiskBRCA1Disease-associated mutationsBRCA2
1996
Major Depression in Alzheimer's Disease An Interaction Between Gender and Family History
Lyketsos C, Tune L, Pearlson G, Steele C. Major Depression in Alzheimer's Disease An Interaction Between Gender and Family History. Journal Of The Academy Of Consultation-Liaison Psychiatry 1996, 37: 380-384. PMID: 8701017, DOI: 10.1016/s0033-3182(96)71552-9.Peer-Reviewed Original Research
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply