2022
A Bedside Test to Detect the Presence of Embryonic or Fetal Tissue in Vaginal Blood
Volovsky M, Ayala M, Narayanamoorthy S, Chiware T, Kotlyar A, Taylor H, Seifer D, Mor A. A Bedside Test to Detect the Presence of Embryonic or Fetal Tissue in Vaginal Blood. Obstetrics And Gynecology 2022, 140: 983-988. PMID: 36357961, DOI: 10.1097/aog.0000000000004975.Peer-Reviewed Original ResearchConceptsVaginal bloodEctopic pregnancyPositive control groupAlpha-fetoproteinControl groupFetal tissuesNegative control groupComplete miscarriageIGFBP-1Bedside testStudy groupInsulin-like growth factor-binding protein-1Growth factor-binding protein-1First-trimester bleedingProspective cohort studyRapid bedside testIntrauterine pregnancyVaginal bleedingCohort studyNonpregnant individualsReproductive-aged individualsPregnant individualsRapid test stripPregnancyMiscarriage
2015
Effects of tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells
Guzel E, Buchwalder L, Basar M, Kayisli U, Ocak N, Bozkurt I, Lockwood CJ, Schatz F. Effects of tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells. Gynecological Endocrinology 2015, 31: 414-418. PMID: 25856298, DOI: 10.3109/09513590.2015.1014788.Peer-Reviewed Original ResearchMeSH KeywordsBlotting, WesternContraceptive Agents, FemaleDexamethasoneEndometriumEnzyme-Linked Immunosorbent AssayEstradiolEstrenesEstrogen Receptor ModulatorsEstrogensFemaleFuransGlucocorticoidsHormone AntagonistsHumansInsulin-Like Growth Factor Binding Protein 1Medroxyprogesterone AcetateMifepristoneNorpregnanesNorpregnenesProlactinReal-Time Polymerase Chain ReactionRNA, MessengerStromal CellsConceptsHuman endometrial stromal cellsCultured human endometrial stromal cellsInsulin-like growth factorEndometrial stromal cellsIGFBP-1RT/PCRTibolone administrationStromal cellsGrowth factorEffects of tiboloneProlactin expressionProtein-1 expressionEndometrial atrophyTibolone metabolitesWestern blot analysisEndometrial bleedingMedroxyprogesterone acetateProlactin levelsTiboloneSpecific ELISAChronic effectsProlactin outputProtein 1ELISA resultsBlot analysis
2010
Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions
Cakmak H, Taylor H. Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions. Seminars In Reproductive Medicine 2010, 28: 069-074. PMID: 20104430, PMCID: PMC3107856, DOI: 10.1055/s-0029-1242996.Peer-Reviewed Original ResearchConceptsProgesterone receptor expressionEndometriosis-related infertilityEndometrium of womenExpression of HOXA10Progesterone-responsive genesTime of implantationProgesterone target genesHOXA10 gene expressionEndometrial growthIGFBP-1Progesterone resistanceEndometrial receptivityProgesterone responseEutopic endometriumHuman endometriumProgesterone levelsReceptor expressionTreatment resistanceSex steroidsEndometriosisEndometriumDiminished activityAlphavbeta3 integrinHOXA10Women
2004
Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome
Pawelczyk L, Spaczynski RZ, Banaszewska B, Duleba AJ. Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2004, 113: 209-213. PMID: 15063962, DOI: 10.1016/j.ejogrb.2003.09.031.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeQuantitative insulin sensitivity check indexInsulin-like growth factorMetformin therapyBody mass indexIGFBP-1Ovary syndromeHyperinsulinemic womenSerum levelsFree insulin-like growth factorTotal IGF-I levelsGlucose/insulin ratioInsulin sensitivity check indexGrowth factorHyperandrogenic PCOS womenIGFBP-1 concentrationsIGFBP-1 levelsFree testosterone indexIGF-I levelsEnd of therapyProtein 1PCOS womenTestosterone indexCompensatory hyperinsulinemiaMass index
1996
Associations between insulin-like growth factors and their binding proteins and other prognostic indicators in breast cancer
Yu H, Levesque M, Khosravi M, Papanastasiou-Diamandi A, Clark G, Diamandis E. Associations between insulin-like growth factors and their binding proteins and other prognostic indicators in breast cancer. British Journal Of Cancer 1996, 74: 1242-1247. PMID: 8883411, PMCID: PMC2075943, DOI: 10.1038/bjc.1996.523.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorProstate-specific antigenIGFBP-3IGF-IIBreast cancerS-phase fractionIGFBP-1Prognostic indicatorGrowth factorActive insulin-like growth factorsHER-2/neu proteinUnfavourable prognostic indicatorPrimary breast cancerEpidermal growth factor receptorSteroid hormone receptorsTumor tissue cytosolGrowth factor receptorIGF functionEstrogen receptorDNA ploidyPossible associationNeu proteinCancerTissue cytosolsHormone receptors
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