2022
Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial
Taylor H, Li HJ, Carson S, Flores V, Pal L, Robbins J, Santoro NF, Segars JH, Seifer D, Huang H, Young S, Zhang H. Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial. BMJ Open 2022, 12: e052043. PMID: 35715184, PMCID: PMC9207753, DOI: 10.1136/bmjopen-2021-052043.Peer-Reviewed Original ResearchConceptsEndometriosis-associated infertilityPlacebo-controlled trialGnRH antagonistFertility treatmentOral GnRH antagonistEndometriosis-related infertilityFertilization-embryo transferLive birth rateUse of gonadotropinsEtiology of infertilityInstitutional review boardAntagonist pretreatmentCommon complicationObstetrical outcomesPeer-reviewed journalsSecondary outcomesIVF treatmentPrimary outcomeHormone agonistImplantation ratePregnancy rateLive birthsEndometriosisLocal protocolsOocyte number
2012
Endometriosis and Infertility A Review of the Pathogenesis and Treatment of Endometriosis-associated Infertility
Macer ML, Taylor HS. Endometriosis and Infertility A Review of the Pathogenesis and Treatment of Endometriosis-associated Infertility. Obstetrics And Gynecology Clinics Of North America 2012, 39: 535-549. PMID: 23182559, PMCID: PMC3538128, DOI: 10.1016/j.ogc.2012.10.002.Peer-Reviewed Original ResearchConceptsEndometriosis-associated infertilityEndometriosis-related infertilityTreatment of endometriosisCurrent treatment optionsPotential future treatmentsCoelomic metaplasiaRetrograde menstruationTreatment optionsIntrauterine inseminationEutopic endometriumFallopian tubeEndometriosis pathogenesisFuture treatmentInfertilityEmbryo transportEndometriosisImpact fertilityPathogenesisTreatmentStem cellsA ReviewMetaplasiaEndometriumSurgeryMenstruation
2010
Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions
Cakmak H, Taylor H. Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions. Seminars In Reproductive Medicine 2010, 28: 069-074. PMID: 20104430, PMCID: PMC3107856, DOI: 10.1055/s-0029-1242996.Peer-Reviewed Original ResearchConceptsProgesterone receptor expressionEndometriosis-related infertilityEndometrium of womenExpression of HOXA10Progesterone-responsive genesTime of implantationProgesterone target genesHOXA10 gene expressionEndometrial growthIGFBP-1Progesterone resistanceEndometrial receptivityProgesterone responseEutopic endometriumHuman endometriumProgesterone levelsReceptor expressionTreatment resistanceSex steroidsEndometriosisEndometriumDiminished activityAlphavbeta3 integrinHOXA10Women
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply