2025
Environmental Protective and Risk Factors for Gastric Cancer: An Umbrella Review and Reanalysis of Meta-Analyses
Kim S, Kim M, Kwon Y, Min J, Alromi A, Kim J, Kim J, Shin J, Yon D, Chu Y, Park S. Environmental Protective and Risk Factors for Gastric Cancer: An Umbrella Review and Reanalysis of Meta-Analyses. Journal Of Gastric Cancer 2025, 25: 285-302. PMID: 40200873, PMCID: PMC11982512, DOI: 10.5230/jgc.2025.25.e16.Peer-Reviewed Original ResearchConceptsIncreased risk of GCRisk of GCGC riskSystematic reviewMeta-analysesIncreased riskGrading of RecommendationsHeavy alcohol consumptionUmbrella reviewGraded associationGastric cancerHabitual salt intakeDietary habitsAlcohol consumptionEffect estimatesCochrane DatabaseGC preventionGrain consumptionPositive associationReduced riskEnvironmental exposuresRisk factorsHuman T-lymphotropic virus type 1Salt intakeDietary intervention
2024
Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk.
Ni Z, Kundu P, McKean D, Wheeler W, Albanes D, Andreotti G, Antwi S, Arslan A, Bamlet W, Beane-Freeman L, Berndt S, Bracci P, Brennan P, Buring J, Chanock S, Gallinger S, Gaziano J, Giles G, Giovannucci E, Goggins M, Goodman P, Haiman C, Hassan M, Holly E, Hung R, Katzke V, Kooperberg C, Kraft P, LeMarchand L, Li D, McCullough M, Milne R, Moore S, Neale R, Oberg A, Patel A, Peters U, Rabe K, Risch H, Shu X, Smith-Byrne K, Visvanathan K, Wactawski-Wende J, White E, Wolpin B, Yu H, Zeleniuch-Jacquotte A, Zheng W, Zhong J, Amundadottir L, Stolzenberg-Solomon R, Klein A. Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk. Cancer Epidemiology Biomarkers & Prevention 2024, 33: 1229-1239. PMID: 38869494, PMCID: PMC11928872, DOI: 10.1158/1055-9965.epi-24-0096.Peer-Reviewed Original ResearchConceptsPancreatic cancer riskHeavy alcohol consumptionCancer riskSingle-nucleotide polymorphismsAlcohol consumptionExpression quantitative trait lociQuantitative trait lociAssociated with pancreatic cancer riskGenome-wide interaction analysisGenome-wide significant evidenceEtiology of pancreatic cancerFixed-effect meta-analysesGenomic regionsGenome-wide significant evidence of associationLead single-nucleotide polymorphismsTrait lociGenetic variantsEuropean ancestry populationsEvidence of associationGenome-wide association studiesAnalysis of single-nucleotide polymorphismsCase-control studyPancreatic cancerGenome-wide analysisAncestry populations
2022
A new monocyte epigenetic clock reveals nonlinear effects of alcohol consumption on biological aging in three independent cohorts (N = 2242)
Liang X, Sinha R, Justice AC, Cohen MH, Aouizerat BE, Xu K. A new monocyte epigenetic clock reveals nonlinear effects of alcohol consumption on biological aging in three independent cohorts (N = 2242). Alcohol Clinical And Experimental Research 2022, 46: 736-748. PMID: 35257385, PMCID: PMC9117474, DOI: 10.1111/acer.14803.Peer-Reviewed Original Research
2018
An mHealth Intervention to Improve Young Gay and Bisexual Men’s Sexual, Behavioral, and Mental Health in a Structurally Stigmatizing National Context
Leluțiu-Weinberger C, Manu M, Ionescu F, Dogaru B, Kovacs T, Dorobănțescu C, Predescu M, Surace A, Pachankis JE. An mHealth Intervention to Improve Young Gay and Bisexual Men’s Sexual, Behavioral, and Mental Health in a Structurally Stigmatizing National Context. JMIR MHealth And UHealth 2018, 6: e183. PMID: 30429117, PMCID: PMC6262207, DOI: 10.2196/mhealth.9283.Peer-Reviewed Original ResearchPre-post intervention assessmentsRecent HIV testingHigh prevalence countriesHIV risk reductionYoung gayHIV prevention interventionsFuture efficacy testingHeavy alcohol consumptionMental health outcomesHIV testingLarge trialsHIV transmissionPreliminary efficacyHIV riskCondomless sexCognitive-behavioral skillsMHealth interventionsAlcohol consumptionHealth outcomesInadequate preventionPilot interventionHealth interventionsCondom useMinimum doseStrong acceptability
2016
Exploring the Utility of Web-Based Social Media Advertising to Recruit Adult Heavy-Drinking Smokers for Treatment
Bold KW, Hanrahan TH, O'Malley SS, Fucito LM. Exploring the Utility of Web-Based Social Media Advertising to Recruit Adult Heavy-Drinking Smokers for Treatment. Journal Of Medical Internet Research 2016, 18: e107. PMID: 27194456, PMCID: PMC4889869, DOI: 10.2196/jmir.5360.Peer-Reviewed Original ResearchConceptsHeavy drinking smokersWeb-based surveyScreening eligibilityAdult smokersAlcohol useCurrent treatment goalsMajority of smokersGreater New HavenHeavy alcohol consumptionSerious medical problemNon-heavy drinkersPerson followDaily smokingTreatment goalsSmokersSmoking behaviorAlcohol consumptionHealth outcomesHeavy drinkersScreening surveyMedical problemsTreatment studiesSmokingInitial eligibilityCertain subgroups
2015
Advancing Behavioral HIV Prevention: Adapting an Evidence‐Based Intervention for People Living with HIV and Alcohol Use Disorders
Armstrong ML, LaPlante AM, Altice FL, Copenhaver M, Molina PE. Advancing Behavioral HIV Prevention: Adapting an Evidence‐Based Intervention for People Living with HIV and Alcohol Use Disorders. AIDS Research And Treatment 2015, 2015: 879052. PMID: 26697216, PMCID: PMC4678056, DOI: 10.1155/2015/879052.Peer-Reviewed Original ResearchEvidence-based interventionsAlcohol use disorderDisease progressionHIV preventionUse disordersAlcohol consumptionHIV primary care clinicHolistic Health Recovery ProgramAdapted evidence-based interventionSecondary HIV preventionHIV disease progressionAntiretroviral therapy adherencePrimary care clinicsSuboptimal treatment adherenceHIV risk behaviorsHeavy alcohol consumptionBehavioral HIV preventionHarmful alcohol consumptionHeavy alcohol useHIV/AIDSFocus groupsCare clinicsTherapy adherenceTreatment adherenceOutpatient options
2013
Childhood adversity moderates the effect of ADH1B on risk for alcohol‐related phenotypes in Jewish Israeli drinkers
Meyers JL, Shmulewitz D, Wall MM, Keyes KM, Aharonovich E, Spivak B, Weizman A, Frisch A, Edenberg HJ, Gelernter J, Grant BF, Hasin D. Childhood adversity moderates the effect of ADH1B on risk for alcohol‐related phenotypes in Jewish Israeli drinkers. Addiction Biology 2013, 20: 205-214. PMID: 24164917, PMCID: PMC3999313, DOI: 10.1111/adb.12102.Peer-Reviewed Original ResearchConceptsADH1B rs1229984Childhood adversityAUD severityAlcohol consumptionHeavy alcohol consumptionEnvironmental risk factorsAdult household residentsEarly life adversityMaximum drinksAUD symptom severityRisk factorsAlcohol metabolismSymptom severityLife adversityAlcohol-related phenotypesSeverityDisorder severityGenetic vulnerabilityAdolescent binge drinking and risky health behaviours: Findings from northern Russia
Stickley A, Koyanagi A, Koposov R, Razvodovsky Y, Ruchkin V. Adolescent binge drinking and risky health behaviours: Findings from northern Russia. Drug And Alcohol Dependence 2013, 133: 838-844. PMID: 24080314, DOI: 10.1016/j.drugalcdep.2013.08.028.Peer-Reviewed Original ResearchConceptsHealth risk behaviorsAdolescent binge drinkingBinge drinkingRisk behaviorsHeavy alcohol consumptionLogistic regression analysisFrequency of bingeNon-condom usePublic health interventionsAdolescent health risk behaviorsRisky health behaviorsRisky sexual behaviorAlcohol consumptionHealth behaviorsLast sexHealth interventionsHeavy drinkingAccessibility of alcoholSubstance useStrong associationPrevalenceNumber of daysSexual behaviorHealth assessmentDrinking
2012
Alcohol Expectancies, Alcohol Use, and Hostility as Longitudinal Predictors of Alcohol-Related Aggression
Kachadourian LK, Homish GG, Quigley BM, Leonard KE. Alcohol Expectancies, Alcohol Use, and Hostility as Longitudinal Predictors of Alcohol-Related Aggression. Psychology Of Addictive Behaviors 2012, 26: 414-422. PMID: 22004128, PMCID: PMC4030542, DOI: 10.1037/a0025842.Peer-Reviewed Original ResearchConceptsAlcohol-related aggressionAlcohol-aggression expectanciesAggression expectanciesPhysical aggressionDispositional hostilityAlcohol expectanciesAlcohol effectsPrevious longitudinal researchLongitudinal predictorsYears of marriageAlcohol consumptionLongitudinal researchOwn behaviorAggressionAlcohol useMarried couplesHostilityPrevious researchInteractive effectsExpectancyHeavy alcohol consumptionHusbandsBehaviorFindingsResearch
2011
Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery
Cornman-Homonoff J, Kuehn D, Aros S, Carter TC, Conley MR, Troendle J, Cassorla F, Mills JL. Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery. The Journal Of Maternal-Fetal & Neonatal Medicine 2011, 25: 860-863. PMID: 21728738, PMCID: PMC4148070, DOI: 10.3109/14767058.2011.587559.Peer-Reviewed Original ResearchConceptsPreterm deliveryStillbirth rateDrinks/dayRisk of stillbirthPrenatal alcohol useHeavy alcohol consumptionPrenatal alcohol exposureHeavy prenatal alcohol exposurePreterm birthPreterm ratePregnant womenAlcohol exposureAlcohol consumptionStillbirthAlcohol useWomenPopulation ratesAdditional investigationRiskDeliveryPregnancy
2003
NMDA Receptor Antagonism and the Ethanol Intoxication Signal
KRYSTAL JH, PETRAKIS IL, KRUPITSKY E, SCHÜTZ C, TREVISAN L, D'SOUZA DC. NMDA Receptor Antagonism and the Ethanol Intoxication Signal. Annals Of The New York Academy Of Sciences 2003, 1003: 176-184. PMID: 14684445, DOI: 10.1196/annals.1300.010.Peer-Reviewed Original Research
1982
Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery
Berkowitz G, Holford T, Berkowitz R. Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery. Early Human Development 1982, 7: 239-250. PMID: 7160334, DOI: 10.1016/0378-3782(82)90086-x.Peer-Reviewed Original ResearchConceptsPreterm deliveryMothers of singletonsTea consumptionTerm infantsCigarette smokingRisk factorsYale-New Haven HospitalHeavy tea consumptionPossible risk factorsCase-control studyHeavy alcohol consumptionPreterm infantsMore cigarettesMore cupsCoffee drinkingAlcohol consumptionInfantsSmokingSignificant relationWomenDeliveryMothersRiskDaysSingletons
1979
Nonalcoholic liver disease Overlooked causes of liver injury in patients with heavy alcohol consumption
Levin D, Baker A, Riddell R, Rochman H, Boyer J. Nonalcoholic liver disease Overlooked causes of liver injury in patients with heavy alcohol consumption. The American Journal Of Medicine 1979, 66: 429-434. PMID: 433949, DOI: 10.1016/0002-9343(79)91064-7.Peer-Reviewed Original ResearchConceptsAlcoholic liver diseaseNonalcoholic liver diseaseLiver diseaseLiver biopsyHeavy alcohol consumptionAlcohol consumptionHepatitis B surface antigenSerum glutamic oxaloacetic transaminaseB surface antigenGlutamic oxaloacetic transaminaseAcute hepatitisChronic hepatitisTransaminase ratioConsecutive patientsLiver injuryAppropriate therapyClinical featuresLiver disordersOverlooked causeAlcoholic subjectsPatientsSurface antigenOxaloacetic transaminaseBiopsyDisease
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