2024
Advances in discovery of novel investigational agents for functional cure of chronic hepatitis B: A comprehensive review of phases II and III therapeutic agents
Lam R, Lim J. Advances in discovery of novel investigational agents for functional cure of chronic hepatitis B: A comprehensive review of phases II and III therapeutic agents. World Journal Of Hepatology 2024, 16: 331-343. PMID: 38577537, PMCID: PMC10989302, DOI: 10.4254/wjh.v16.i3.331.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFunctional cure of chronic hepatitis BCure of chronic hepatitis BNovel investigational agentsChronic hepatitis BFunctional cureHepatitis B virusInvestigational agentsHepatitis BSuppression of HBV DNARisk of liver complicationsChronic hepatitis B virusAssociated with significant morbidityToll-like receptor agonistsOral nucleos(t)ide analoguesHepatitis B surface antigenB surface antigenLong-term treatmentAssociated with higher ratesMortality due to cirrhosisCheckpoint inhibitorsNucleos(t)ide analoguesVirologic suppressionPhase IIAntiviral regimensIII trials
2023
Implementation of a Best Practice Advisory to Improve Infection Screening Prior to New Prescriptions of Biologics and Targeted Synthetic Drugs
Baker H, Fine R, Suter F, Allore H, Hsiao B, Chowdhary V, Lavelle E, Chen P, Hintz R, Suter L, Danve A. Implementation of a Best Practice Advisory to Improve Infection Screening Prior to New Prescriptions of Biologics and Targeted Synthetic Drugs. Arthritis Care & Research 2023, 77: 273-281. PMID: 37382043, DOI: 10.1002/acr.25181.Peer-Reviewed Original ResearchBest practice advisoryHepatitis B virusAutoimmune rheumatic diseasesBPA implementationSynthetic disease-modifying antirheumatic drugsDisease-modifying antirheumatic drugsHepatitis C virus infectionHepatitis B surface antigenC virus infectionUse of biologicsB surface antigenQuality improvement initiativesElectronic health recordsEligible patientsAntirheumatic drugsRheumatic diseasesRheumatology practiceSociety guidelinesB virusPractice advisoryComputerized decision support systemVirus infectionRoutine screeningPatient screeningPatients
2021
Hepatitis B Awareness Campaign in Chinese Americans: A Community Outreach Model to Facilitate Screening and Linkage to Care
Hyun C, Wang H, Ko O, Lee S, McMenamin J. Hepatitis B Awareness Campaign in Chinese Americans: A Community Outreach Model to Facilitate Screening and Linkage to Care. International Journal Of Health Promotion And Education 2021, 59: 366-377. DOI: 10.1080/14635240.2021.1964375.Peer-Reviewed Original ResearchHepatitis B virusAccessing CareChronic hepatitis BChinese AmericansLinkage-to-careChinese-American adultsCommunity outreach modelChinese-AmericansPrevalence of chronic HBV infectionHepatitis B virus-infected individualsScreening educationHepatitis B virus prevalenceHepatitis B surface antigenChronic HBV infectionAwareness of infectionAdequate careOutreach modelPatient awarenessB surface antigenLiver-related morbidityInadequate educationCareSeropositive subjectsHBV infectionHepatitis B
2019
The prevalence and significance of isolated hepatitis B core antibody (anti-HBc) in endemic population
Hyun C, Lee S, Ventura W. The prevalence and significance of isolated hepatitis B core antibody (anti-HBc) in endemic population. BMC Research Notes 2019, 12: 251. PMID: 31060623, PMCID: PMC6501423, DOI: 10.1186/s13104-019-4287-z.Peer-Reviewed Original ResearchConceptsHepatitis B virusPrevalence of isolated anti-HBcHepatitis B core antibodyIsolated anti-HBcAnti-HBcAnti-HBsRisk of HBV reactivationSusceptibility to hepatitis B virusPrevalence of hepatitis B virusPrevalence of HBV exposureHepatitis B virus infectionHepatitis B virus screening programHepatitis B surface antibodyHepatitis B surface antigenB surface antigenModerate to high riskNon-immune populationHBV reactivationHBV exposureChronic infectionSerological markersB virusHBV screeningScreening programHBsAg
2017
Comparing Child-Pugh, MELD, and FIB-4 to Predict Clinical Outcomes in Hepatitis C Virus-Infected Persons: Results From ERCHIVES
Butt AA, Ren Y, Re V, Taddei T, Kaplan DE. Comparing Child-Pugh, MELD, and FIB-4 to Predict Clinical Outcomes in Hepatitis C Virus-Infected Persons: Results From ERCHIVES. Clinical Infectious Diseases 2017, 65: 64-72. PMID: 28369305, DOI: 10.1093/cid/cix224.Peer-Reviewed Original ResearchConceptsHCV-positive personsHepatic decompensationFIB-4 scoreHuman immunodeficiency virusFIB-4Hepatocellular carcinomaCause mortalityLower riskHCV diagnosisClinical outcomesHepatitis C virus-infected personsHepatitis B surface antigenCohort of HCVVirus-infected personsB surface antigenHepatitis C virusChild-TurcotteChild-PughEarly complicationsMELD scoreImmunodeficiency virusC virusIncidence ratePositive personsTreatment decisions
2016
Chronic hepatitis B in Korean Americans: decreased prevalence and poor linkage to care
Hyun C, Kim S, Kang S, Jung S, Lee S. Chronic hepatitis B in Korean Americans: decreased prevalence and poor linkage to care. BMC Infectious Diseases 2016, 16: 415. PMID: 27526685, PMCID: PMC4986342, DOI: 10.1186/s12879-016-1732-7.Peer-Reviewed Original ResearchConceptsLinkage-to-careKorean AmericansSusceptible to HBVKorean American adultsSelf-administered questionnaireHepatitis B virus(HBV) infectionAsian American populationHBV prevalencePrevalence of chronic HBVHigh-risk populationAccessing CareHBV-infected subjectsHepatitis B surface antibodyHepatitis B surface antigenChronic hepatitis BCompared to femalesClinical carePoor linkageRate of HBsAgB surface antigenImpact of HBVLiver related morbidityAmerican adultsHistory of infectionHBV screeningP-220 To Assess the Rate of Adequate Immune Response to Primary Hepatitis B Vaccination Series in Patients with IBD
Phatak U, Rojas-Velasquez D, Pashankar D. P-220 To Assess the Rate of Adequate Immune Response to Primary Hepatitis B Vaccination Series in Patients with IBD. Inflammatory Bowel Diseases 2016, 22: s76-s76. DOI: 10.1097/01.mib.0000480330.52952.bf.Peer-Reviewed Original ResearchInflammatory bowel diseaseAdequate immune responseType of IBDHep B vaccinationAnti-TNF therapyImmune responseHBsAb levelsVaccination seriesHep BB vaccinationMIU/General populationHepatitis B vaccination seriesYale-New Haven Children's HospitalHepatitis B surface antigenHepatitis B surface antibodyPrimary vaccination seriesPercent of patientsPresence of obesityRetrospective chart reviewHepatitis B vaccineInadequate immune responseUse of immunomodulatorsB surface antigenB surface antibody
2013
Combining rapid diagnostic tests and dried blood spot assays for point-of-care testing of human immunodeficiency virus, hepatitis B and hepatitis C infections in Burkina Faso, West Africa
Kania D, Bekalé A, Nagot N, Mondain A, Ottomani L, Meda N, Traoré M, Ouédraogo J, Ducos J, Van de Perre P, Tuaillon E. Combining rapid diagnostic tests and dried blood spot assays for point-of-care testing of human immunodeficiency virus, hepatitis B and hepatitis C infections in Burkina Faso, West Africa. Clinical Microbiology And Infection 2013, 19: e533-e541. PMID: 23902574, DOI: 10.1111/1469-0691.12292.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusRapid diagnostic testsDried Blood SpotsHepatitis C infectionC infectionHepatitis BImmunodeficiency virusDBS specimensImmunoblot assayBlood spotsHepatitis B surface antigenDiagnostic testsHIV-positive testPost-test counselling sessionsB surface antigenHIV rapid diagnostic testsLow HBsAg concentrationsTwo-step screening strategyCare testingHCV statusHIV confirmationHCV antibodiesHCV infectionHIV screeningHIV ELISA
2011
HIV, hepatitis B, and hepatitis C in Zambia
Kapembwa KC, Goldman JD, Lakhi S, Banda Y, Bowa K, Vermund SH, Mulenga J, Chama D, H BH. HIV, hepatitis B, and hepatitis C in Zambia. Journal Of Global Infectious Diseases 2011, 3: 269-274. PMID: 21887060, PMCID: PMC3162815, DOI: 10.4103/0974-777x.83534.Peer-Reviewed Original ResearchHepatitis B coinfectionAntiretroviral therapyHepatitis BElevated AST/ALTHepatitis B surface antigenActive hepatitis BART-eligible adultsViral hepatitis coinfectionElevated liver enzymesHepatitis C antibodyHepatitis C infectionAST/ALTTertiary care facilityB surface antigenHCV AbHepatitis coinfectionC infectionHepatitis CHepatitis screeningTertiary hospitalLiver enzymesEpidemiologic dataC antibodyLow prevalenceCare facilitiesLow prevalence of HBV DNA in the liver allograft from anti‐HBc‐positive donors: a single‐center experience
Pan J, Oh S, Soldevila‐Pico C, Nelson D, Liu C. Low prevalence of HBV DNA in the liver allograft from anti‐HBc‐positive donors: a single‐center experience. Clinical Transplantation 2011, 25: 164-170. PMID: 20156222, PMCID: PMC3480317, DOI: 10.1111/j.1399-0012.2010.01211.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiviral AgentsCase-Control StudiesDNA, ViralFemaleFollow-Up StudiesGraft SurvivalHepatitis BHepatitis B AntibodiesHepatitis B Core AntigensHepatitis B Surface AntigensHepatitis B virusHumansImmunoenzyme TechniquesLiver TransplantationMaleMiddle AgedPolymerase Chain ReactionPrevalenceRetrospective StudiesSurvival RateTissue DonorsTransplantation, HomologousTreatment OutcomeVirus ActivationConceptsHepatitis B virusDetectable HBV DNAHBV DNALiver allograftsLow prevalenceDe novo hepatitis B.Serum HBV DNA levelsHepatitis B core antigenHepatitis B surface antigenHBV DNA levelsSingle-center experienceB core antigenLiver biopsy tissueB surface antigenViral protein expressionHBV serologySeronegative recipientsHBV infectionHepatitis B.Such prophylaxisPositive donorsCore antigenRetrospective studyB virusProphylaxis
2006
Cystic Fibrosis in an Adolescent Being Evaluated for Primary Sclerosing Cholangitis
Sinha J, Morotti R, Norton K, Gold D, Shneider B. Cystic Fibrosis in an Adolescent Being Evaluated for Primary Sclerosing Cholangitis. Seminars In Liver Disease 2006, 26: 080-084. PMID: 16496236, DOI: 10.1055/s-2006-933566.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisWhite blood cell countMagnetic resonance cholangiogramMagnetic resonance cholangiopancreatographyHistory of hypothyroidismSclerosing cholangitisExtrahepatic biliary systemBiliary cirrhosisBile ductPortal tractsCystic fibrosisAlanine aminotransferaseAspartate aminotransferaseFatty pancreasMuscle antibodiesHepatic ductLiver diseasePathologic findingsPersistent elevationBiliary systemPercutaneous liver needle biopsyHepatitis B surface antigenHepatitis B surface antibodyAntinuclear antibody analysisAntismooth muscle antibodies
2001
Isoniazid Preventive Therapy, Hepatitis C Virus Infection, and Hepatotoxicity among Injection Drug Users Infected with Mycobacterium tuberculosis
Sadaphal P, Astemborski J, Graham N, Sheely L, Bonds M, Madison A, Vlahov D, Thomas D, Sterling T. Isoniazid Preventive Therapy, Hepatitis C Virus Infection, and Hepatotoxicity among Injection Drug Users Infected with Mycobacterium tuberculosis. Clinical Infectious Diseases 2001, 33: 1687-1691. PMID: 11641824, PMCID: PMC2650436, DOI: 10.1086/323896.Peer-Reviewed Original ResearchConceptsHepatitis C virusInjection drug usersTuberculosis infectionValue elevationDrug usersCurrent injection drug useLatent Mycobacterium tuberculosis infectionHepatitis C virus infectionHepatitis B surface antigenLow HCV prevalenceC virus infectionIsoniazid preventive therapyInjection drug useM. tuberculosis infectionMycobacterium tuberculosis infectionHIV-1 infectionHuman immunodeficiency virusB surface antigenConcurrent alcohol useDrug discontinuationHCV prevalencePreventive therapyImmunodeficiency virusProspective studyTransaminase values
1999
Immune Responses Induced by Gene Gun or Intramuscular Injection of DNA Vaccines That Express Immunogenic Regions of the Serine Repeat Antigen from Plasmodium falciparum
Belperron A, Feltquate D, Fox B, Horii T, Bzik D. Immune Responses Induced by Gene Gun or Intramuscular Injection of DNA Vaccines That Express Immunogenic Regions of the Serine Repeat Antigen from Plasmodium falciparum. Infection And Immunity 1999, 67: 5163-5169. PMID: 10496891, PMCID: PMC96866, DOI: 10.1128/iai.67.10.5163-5169.1999.Peer-Reviewed Original ResearchConceptsSerine repeat antigenHuman malaria vaccineGene gun immunizationImmunization of miceMalaria vaccineDNA vaccineIntramuscular injectionImmune responseProtein-based subunit vaccinesImmunogenic regionHepatitis B surface antigenHigh serum antibody titersPlasmodium falciparumCoimmunization of miceMinimal antibody responseSerum antibody titersB surface antigenSERA proteinPlasmid DNA vaccineGene gun deliveryAntibody titersAntibody responseDNA vaccinationSubunit vaccineSurface antigen
1995
Risk Factors for HTLV-I Among Heterosexual STD Clinic Attenders
Figueroa JP, Morris J, Brathwaite A, Ward E, Peruga A, Hayes R, Vermund SH, Blattner W. Risk Factors for HTLV-I Among Heterosexual STD Clinic Attenders. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1995, 9: 81-88. PMID: 7712238, DOI: 10.1097/00042560-199505010-00012.Peer-Reviewed Original ResearchConceptsFirst sexual intercourseHuman immunodeficiency virus (HIV) infectionMultiple logistic regression analysisHepatitis B surface antigenSexual intercourseImmunodeficiency virus infectionMore lifetime sexual partnersSTD clinic attendersHTLV-I infectionB surface antigenLogistic regression analysisLifetime sexual partnersMore sex partnersBlood transfusionClinic attendersDisease clinicIndependent associationRisk factorsVirus infectionPositive testSurface antigenSex partnersSexual partnersHTLVMarital statusOccupational risk of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infections among funeral service practitioners in Maryland.
Gershon R, Vlahov D, Farzadegan H, Alter M. Occupational risk of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infections among funeral service practitioners in Maryland. Infection Control And Hospital Epidemiology 1995, 16: 194-7. PMID: 7636165, DOI: 10.1086/647089.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis B virusHepatitis B vaccinationHepatitis C virusB vaccinationImmunodeficiency virusBloodborne pathogensB virusNon-occupational risk factorsHepatitis C virus infectionHepatitis B surface antigenHepatitis B surface antibodyBloodborne pathogen infectionsC virus infectionDoses of vaccineHepatitis B vaccineB surface antigenMarker of protectionB surface antibodyAdequate titersBloodborne exposuresHBV infectionHCV infectionB vaccineHIV infectionOccupational Risk of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infections Among Funeral Service Practitioners in Maryland
Gershon R, Vlahov D, Farzadegan H, Alter M. Occupational Risk of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infections Among Funeral Service Practitioners in Maryland. Infection Control And Hospital Epidemiology 1995, 16: 194-197. DOI: 10.2307/30140977.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis B virusHepatitis B vaccinationHepatitis C virusB vaccinationImmunodeficiency virusBloodborne pathogensB virusNon-occupational risk factorsHepatitis C virus infectionHepatitis B surface antigenHepatitis B surface antibodyBloodborne pathogen infectionsC virus infectionDoses of vaccineHepatitis B vaccineB surface antigenMarker of protectionB surface antibodyAdequate titersBloodborne exposuresHBV infectionHCV infectionB vaccineHIV infection
1988
Low Occupational Risk of Human Immunodeficiency Virus Infection among Dental Professionals
Klein R, Phelan J, Freeman K, Schable C, Friedland G, Trieger N, Steigbigel N. Low Occupational Risk of Human Immunodeficiency Virus Infection among Dental Professionals. New England Journal Of Medicine 1988, 318: 86-90. PMID: 3422106, DOI: 10.1056/nejm198801143180205.Peer-Reviewed Original ResearchMeSH KeywordsAccidents, OccupationalAcquired Immunodeficiency SyndromeAntibodies, ViralDental AssistantsDental HygienistsDentistryFemaleHepatitis B Surface AntigensHIV AntibodiesHumansMaleNew York CityOccupational DiseasesProfessional PracticePuncturesRisk FactorsSkinSurveys and QuestionnairesUnited StatesConceptsHuman immunodeficiency virusHepatitis B surface antigenBehavioral risk factorsInfection control practicesB surface antigenLow occupational riskDental professionalsOccupational riskHIV infectionRisk factorsOccupational exposureSurface antigenHuman immunodeficiency virus (HIV) infectionFrequent occupational exposureImmunodeficiency virus infectionInfection control precautionsCases of AIDSPotential occupational exposureUnvaccinated subjectsImmunodeficiency syndromeImmunodeficiency virusSerum antibodiesVirus infectionDental practiceSharp instruments
1979
Nonalcoholic liver disease Overlooked causes of liver injury in patients with heavy alcohol consumption
Levin D, Baker A, Riddell R, Rochman H, Boyer J. Nonalcoholic liver disease Overlooked causes of liver injury in patients with heavy alcohol consumption. The American Journal Of Medicine 1979, 66: 429-434. PMID: 433949, DOI: 10.1016/0002-9343(79)91064-7.Peer-Reviewed Original ResearchConceptsAlcoholic liver diseaseNonalcoholic liver diseaseLiver diseaseLiver biopsyHeavy alcohol consumptionAlcohol consumptionHepatitis B surface antigenSerum glutamic oxaloacetic transaminaseB surface antigenGlutamic oxaloacetic transaminaseAcute hepatitisChronic hepatitisTransaminase ratioConsecutive patientsLiver injuryAppropriate therapyClinical featuresLiver disordersOverlooked causeAlcoholic subjectsPatientsSurface antigenOxaloacetic transaminaseBiopsyDisease
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply