2021
Variation in Antithrombotic Therapy and Clinical Outcomes in Patients With Preexisting Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement
Sherwood M, Gupta A, Vemulapalli S, Li Z, Piccini J, Harrison J, Dai D, Vora A, Mack M, Holmes D, Rumsfeld J, Cohen D, Thourani V, Kirtane A, Peterson E. Variation in Antithrombotic Therapy and Clinical Outcomes in Patients With Preexisting Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement. Circulation Cardiovascular Interventions 2021, 14: e009963. PMID: 33877866, PMCID: PMC8300574, DOI: 10.1161/circinterventions.120.009963.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementOral anticoagulantsRisk of bleedingValve replacementAntithrombotic therapyAntiplatelet therapyAtrial fibrillationOutcome of strokeReceipt of oral anticoagulationSociety of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy RegistryAssociated with increased risk of bleeding complicationsUnderuse of oral anticoagulantsRisk of bleeding complicationsOptimal antithrombotic managementTranscatheter Valve Therapy RegistryConcomitant atrial fibrillationOral anticoagulant therapyAssociated with increased riskAntithrombotic management of patientsHigh-risk cohortManagement of patientsPatient- and hospital-level variablesRisk of strokeBleeding complications
2020
Incidence, Temporal Trends, and Associated Outcomes of Vascular and Bleeding Complications in Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement
Sherwood M, Xiang K, Matsouaka R, Li Z, Vemulapalli S, Vora A, Fanaroff A, Harrison J, Thourani V, Holmes D, Kirtane A, Pineda A, Peterson E, Rao S. Incidence, Temporal Trends, and Associated Outcomes of Vascular and Bleeding Complications in Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement. Circulation Cardiovascular Interventions 2020, 13: e008227. PMID: 31937138, DOI: 10.1161/circinterventions.119.008227.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCatheterization, PeripheralFemaleFemoral ArteryHospital MortalityHumansIncidenceMalePatient ReadmissionPostoperative HemorrhageRegistriesRisk AssessmentRisk FactorsStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesVascular DiseasesConceptsTranscatheter aortic valve replacementAortic valve replacementIn-hospital bleeding eventsBleeding eventsValve replacementAssociated with 30-day deathVascular complicationsBleeding complicationsClinical outcomesComplication rateTranscatheter aortic valve replacement clinical trialsSociety of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy RegistryAssociated with worse short-Long-term clinical outcomesIn-hospital clinical outcomesTransfemoral transcatheter aortic valve replacementTranscatheter Valve Therapy RegistryIn-hospital vascular complicationsUS clinical practiceAll-Cause MortalityMultivariate logistic regressionAntithrombotic therapyEvaluating patientsVascular/bleeding complicationsDetrimental complications
2018
Variation in post-TAVR antiplatelet therapy utilization and associated outcomes: Insights from the STS/ACC TVT Registry
Sherwood M, Vemulapalli S, Harrison J, Dai D, Vora A, Mack M, Holmes D, Rumsfeld J, Cohen D, Thourani V, Kirtane A, Peterson E. Variation in post-TAVR antiplatelet therapy utilization and associated outcomes: Insights from the STS/ACC TVT Registry. American Heart Journal 2018, 204: 9-16. PMID: 30075326, DOI: 10.1016/j.ahj.2018.06.006.Peer-Reviewed Original ResearchMeSH KeywordsCause of DeathDrug Therapy, CombinationFibrinolytic AgentsHemorrhageHumansMyocardial InfarctionPlatelet Aggregation InhibitorsPostoperative CarePostoperative ComplicationsPractice Patterns, Physicians'Risk FactorsStrokeThrombosisTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementDual antiplatelet therapyPractice patternsAntiplatelet therapyMyocardial infarctionNational Cardiovascular Data RegistryPost-TAVRArtery diseaseSociety of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy RegistryTransfemoral transcatheter aortic valve replacementTranscatheter Valve Therapy RegistryRates of coronary artery diseaseRisk of mortalityOptimal antiplatelet strategyAortic valve replacementDual antiplatelet therapy useOptimal antiplatelet therapyContemporary practice patternsPeripheral arterial diseaseCoronary artery diseaseOutcomes post-TAVRSTS/ACC TVT RegistryService linkagesTherapy utilizationMortality risk
2016
Sex-Based Differences in Outcomes With Transcatheter Aortic Valve Therapy TVT Registry From 2011 to 2014
Chandrasekhar J, Dangas G, Yu J, Vemulapalli S, Suchindran S, Vora A, Baber U, Mehran R, Registry S. Sex-Based Differences in Outcomes With Transcatheter Aortic Valve Therapy TVT Registry From 2011 to 2014. Journal Of The American College Of Cardiology 2016, 68: 2733-2744. PMID: 28007135, DOI: 10.1016/j.jacc.2016.10.041.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic ValveAortic Valve StenosisFemaleFollow-Up StudiesHospital MortalityHumansMaleRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexSex DistributionSex FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementIn-hospital vascular complicationsIn-Hospital OutcomesFemale patientsMale patientsVascular complicationsSociety of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy RegistrySubgroup analyses of randomized trialsPrevalence of coronary artery diseaseLow glomerular filtration rateTranscatheter Valve Therapy RegistryDifferential impact of sexMultivariate logistic regression adjustmentsAortic valve replacementGlomerular filtration rateCoronary artery diseaseLogistic regression adjustmentRisk of deathAnalysis of randomized trialsNontransfemoral accessPorcelain aortaFine-Gray modelCenters for Medicare & Medicaid ServicesValve replacementImpact of sex
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