2025
A Honduran Prevalence Study on Soil-Transmitted Helminths Highlights Serological Antibodies to Tm-WAP49 as a Diagnostic Marker for Exposure to Human Trichuriasis.
Briggs N, Versteeg L, Mejia R, Pollet J, Villar M, Zhan B, Segal G, Novak S, Lenihan P, Musgrave P, Ellis V, Coello C, Sastry K, Craft J, Hotez P, Bottazzi M. A Honduran Prevalence Study on Soil-Transmitted Helminths Highlights Serological Antibodies to Tm-WAP49 as a Diagnostic Marker for Exposure to Human Trichuriasis. American Journal Of Tropical Medicine And Hygiene 2025, 112: 1017-1025. PMID: 39933187, PMCID: PMC12062693, DOI: 10.4269/ajtmh.24-0514.Peer-Reviewed Original ResearchSoil-Transmitted HelminthsReceiver-operating characteristic analysisSerological assaysFecal examinationDiagnostic toolIndirect ELISAGold standard testRoundworm infectionDiseases of humansRecombinant proteinsValidation cohortScreening cohortActive infectionInfections rankControl seraHuman trichuriasisDiagnostic markerRelationship to chronic diseasesClinical questionsWestern blottingDiagnostic potentialInfectionWhipwormCharacteristic analysisPrevalence studies
2024
Prenatal and infant exposure to antibiotics and subsequent risk of neuropsychiatric disorders in children: A nationwide birth cohort study in South Korea
Oh J, Woo H, Kim H, Park J, Lee M, Rahmati M, Rhee S, Min C, Koyanagi A, Smith L, Fond G, Boyer L, Kim M, Shin J, Lee S, Yon D. Prenatal and infant exposure to antibiotics and subsequent risk of neuropsychiatric disorders in children: A nationwide birth cohort study in South Korea. Psychiatry Research 2024, 340: 116117. PMID: 39128166, DOI: 10.1016/j.psychres.2024.116117.Peer-Reviewed Original ResearchConceptsRisk of neuropsychiatric disordersNeuropsychiatric disordersAntibiotic exposureHazard ratioNationwide birth cohort studyHealth Screening CohortPostnatal lifeConfidence intervalsBirth cohort studyFollow-up durationDuration of prescriptionExposure to antibioticsEstimates of hazard ratiosLong-term riskScreening cohortChildhood neuropsychiatric disordersMaternal obesityPropensity score matchingAntibiotic prescriptionsPotential long-term risksCohort studyExposure statusIncreased riskBaseline variablesFamily factorsPrenatal and postnatal exposure to antibiotics and risk of food allergy in the offspring: A nationwide birth cohort study in South Korea
Oh J, Lee M, Park J, Kim H, Lee S, Rahmati M, Koyanagi A, Smith L, Kim M, Sánchez G, Dragioti E, Min C, Papadopoulos N, Shin Y, Shin J, Yon D. Prenatal and postnatal exposure to antibiotics and risk of food allergy in the offspring: A nationwide birth cohort study in South Korea. Pediatric Allergy And Immunology 2024, 35: e14114. PMID: 38529692, DOI: 10.1111/pai.14114.Peer-Reviewed Original ResearchConceptsRisk of food allergyHealth Screening CohortFood allergyAntibiotic exposureScreening cohortPostnatal exposure to antibioticsBirth cohortNationwide birth cohort studyEarly-life antibiotic useDiagnosis of food allergyPostnatal antibiotic exposureFollow-up periodPropensity-matched cohortBenefits of antibioticsNationwide birth cohortTrimester-specific effectsEffects of antibiotic exposureExposure to antibioticsMultiple subgroup analysesBirth cohort studyBorn pretermMaternal BMIPropensity score matchingLow birthweightAntibiotic use
2020
Performance of the Vancouver Risk Calculator Compared with Lung-RADS in an Urban, Diverse Clinical Lung Cancer Screening Cohort
Kessler A, Peng R, Mardakhaev E, Haramati L, White C. Performance of the Vancouver Risk Calculator Compared with Lung-RADS in an Urban, Diverse Clinical Lung Cancer Screening Cohort. Radiology Imaging Cancer 2020, 2: e190021. PMID: 33778703, PMCID: PMC7983652, DOI: 10.1148/rycan.2020190021.Peer-Reviewed Original ResearchConceptsLung CT Screening ReportingLung-RADSFalse-negative findingsRadiology's Lung CT Screening ReportingLung cancer screening cohortAccountability Act-compliant retrospective studyLung cancer screening programsLung-RADS scoreInstitutional review board approvalCancer screening programsLung nodulesLung cancer screeningRisk of cancerReview board approvalDiverse clinical settingsMean followScreening cohortRetrospective studyRisk calculatorCancer screeningLung cancerScreening programStudy populationLung cancer detectionAmerican College
2019
Lung cancer survival and comorbidities in lung cancer screening participants of the Gdańsk screening cohort
Ostrowski M, Marczyk M, Dziedzic R, Jelitto-Górska M, Marjański T, Pisiak S, Jędrzejczyk T, Polańska J, Zdrojewski T, Wojtyniak B, Rzyman W. Lung cancer survival and comorbidities in lung cancer screening participants of the Gdańsk screening cohort. European Journal Of Public Health 2019, 29: 1114-1117. PMID: 31004154, DOI: 10.1093/eurpub/ckz052.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseLung cancer screening programsCancer screening programsCardiovascular diseaseDiabetes mellitusLung cancerScreening programLung cancer detection rateMedical eventsModifiable risk factorsLung cancer survivalObstructive pulmonary diseaseLung cancer patientsCancer detection rateHealth care providersHealth care systemWorld Health OrganizationScreening groupHeavy smokersPulmonary diseaseScreening cohortCancer patientsCancer survivalRisk factorsCare providers
2018
Effectiveness of Lung-RADS in Reducing False-Positive Results in a Diverse, Underserved, Urban Lung Cancer Screening Cohort
Kaminetzky M, Milch H, Shmukler A, Kessler A, Peng R, Mardakhaev E, Bellin E, Levsky J, Haramati L. Effectiveness of Lung-RADS in Reducing False-Positive Results in a Diverse, Underserved, Urban Lung Cancer Screening Cohort. Journal Of The American College Of Radiology 2018, 16: 419-426. PMID: 30146484, DOI: 10.1016/j.jacr.2018.07.011.Peer-Reviewed Original ResearchConceptsLung cancer screening cohortNational Lung Screening TrialPercent of patientsNational Death IndexLung cancer screeningLung-RADSLung cancer ratesCancer ratesScreening cohortDeath IndexCancer screeningLung cancerScreening TrialCT resultsLung CT Screening ReportingFirst annual examinationLung cancer prevalenceLung-RADS 1Lung-RADS 2Lung-RADS 3Institutional review board approvalLung-RADS categoriesClinical screening programReview board approvalUnderserved urban population
2015
MP24-10 DECLINING USE OF URINARY HERBAL AND VITAMIN SUPPLEMENTS AMONG U.S. MEN IN LONGITUDINAL NATIONAL PROSTATE CANCER SCREENING COHORTS
Leapman M, Crawford D, Poage W, Stone N. MP24-10 DECLINING USE OF URINARY HERBAL AND VITAMIN SUPPLEMENTS AMONG U.S. MEN IN LONGITUDINAL NATIONAL PROSTATE CANCER SCREENING COHORTS. Journal Of Urology 2015, 193: e279. DOI: 10.1016/j.juro.2015.02.1152.Peer-Reviewed Original Research
2014
Risk Factors for Death in 632 Patients with Sickle Cell Disease in the United States and United Kingdom
Gladwin M, Barst R, Gibbs J, Hildesheim M, Sachdev V, Nouraie M, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Taylor J, Goldsmith J, Kato G, Gordeuk V, Machado R, Investigators and Patients O. Risk Factors for Death in 632 Patients with Sickle Cell Disease in the United States and United Kingdom. PLOS ONE 2014, 9: e99489. PMID: 24988120, PMCID: PMC4079316, DOI: 10.1371/journal.pone.0099489.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnemia, Sickle CellBlood Flow VelocityBlood PressureCohort StudiesCreatinineFemaleFerritinsFollow-Up StudiesHemolysisHumansHypertension, PulmonaryKaplan-Meier EstimateMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsProportional Hazards ModelsRisk FactorsSeverity of Illness IndexUnited KingdomUnited StatesWalkingConceptsTricuspid regurgitation velocitySickle cell diseaseNT-proBNPCell diseaseMean pulmonary artery pressurePg/Pulmonary artery systolic pressurePulmonary artery pressureRisk of deathCause of mortalityPositive predictive valuePg/mLArtery pressurePulmonary hypertensionChronic transfusionScreening cohortHemolytic markersSystolic pressureCumulative survivalMale genderRisk factorsHigh riskPredictive valueClass IIIPatients
2010
Racial differences in prediction of time to prostate cancer diagnosis in a prospective screening cohort of high‐risk men: effect of TMPRSS2 Met160Val
Giri V, Ruth K, Hughes L, Uzzo R, Chen D, Boorjian S, Viterbo R, Rebbeck T. Racial differences in prediction of time to prostate cancer diagnosis in a prospective screening cohort of high‐risk men: effect of TMPRSS2 Met160Val. BJU International 2010, 107: 466-470. PMID: 20735386, PMCID: PMC3052292, DOI: 10.1111/j.1464-410x.2010.09522.x.Peer-Reviewed Original ResearchConceptsHigh-risk menPCa diagnosisCaucasian manElevated prostate-specific antigen concentrationPCa screeningProstate Cancer Risk Assessment ProgramProstate-specific antigen concentrationCancer Risk Assessment ProgramProspective screening cohortCancer diagnosisProspective screening programCT/TTSecond-degree relativesAfrican American menTMPRSS2-ERG fusionUnderwent biopsyScreening cohortStudy entryAA menDegree relativesScreening programBRCA1/2 mutationsSelf-identified raceCox modelGene polymorphisms
2009
The Influence of Radiographic Phenotype and Smoking Status on Peripheral Blood Biomarker Patterns in Chronic Obstructive Pulmonary Disease
Bon JM, Leader JK, Weissfeld JL, Coxson HO, Zheng B, Branch RA, Kondragunta V, Lee JS, Zhang Y, Choi AM, Lokshin AE, Kaminski N, Gur D, Sciurba FC. The Influence of Radiographic Phenotype and Smoking Status on Peripheral Blood Biomarker Patterns in Chronic Obstructive Pulmonary Disease. PLOS ONE 2009, 4: e6865. PMID: 19718453, PMCID: PMC2730536, DOI: 10.1371/journal.pone.0006865.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseCurrent smoking statusAirway thickeningSmoking statusPulmonary diseaseBiomarker patternsSerum biomarker patternsSerum biomarker profilesSerum inflammatory proteinsParenchymal phenotypesMeasurements of FEV1Cross-sectional studyMultiplex protein arrayUnique biomarker patternsQuantitative CT measurementsCOPD syndromePhysiologic obstructionSecond percentAirway remodelingExpiratory volumeInflammatory markersParenchymal destructionScreening cohortBiological therapy
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