2025
SUSCEPTIBLE PYRAMIDAL NEURONS IN PRIMATE DORSOLATERAL PREFRONTAL CORTEX EXPRESS AN ENRICHED CALCIUM INTERACTOME: CRITICAL ROLE OF CALBINDIN AND CAV1.2 IN HIGHER-ORDER COGNITION
Datta *, Yang S, Joyce M, Woo E, McCarroll S, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman R, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O'dell R, van Dyck C, Lewis D, Wang M, Krienen F, Arnsten A. SUSCEPTIBLE PYRAMIDAL NEURONS IN PRIMATE DORSOLATERAL PREFRONTAL CORTEX EXPRESS AN ENRICHED CALCIUM INTERACTOME: CRITICAL ROLE OF CALBINDIN AND CAV1.2 IN HIGHER-ORDER COGNITION. The International Journal Of Neuropsychopharmacology 2025, 28: i57-i58. PMCID: PMC11814899, DOI: 10.1093/ijnp/pyae059.100.Peer-Reviewed Original ResearchDorsolateral prefrontal cortexMacaque dlPFCPrefrontal cortexWorking memoryLayer 3 pyramidal cellsAlzheimer s diseasePrefrontal cortex dysfunctionExpression of Grin2bPyramidal cellsHigher-order cognitionIncreased risk of mental disordersRisk of neuropsychiatric disordersDendritic spine pathologyRisk of mental disordersIncreased risk of neuropsychiatric disordersL-type calcium channel Cav1.2Primate dlPFCDLPFC functionCognitive deficitsLayer III pyramidal cellsMemory impairmentPsychiatric disordersBrain circuitryNeuropsychiatric disordersMental representations
2024
Prenatal and infant exposure to antibiotics and subsequent risk of neuropsychiatric disorders in children: A nationwide birth cohort study in South Korea
Oh J, Woo H, Kim H, Park J, Lee M, Rahmati M, Rhee S, Min C, Koyanagi A, Smith L, Fond G, Boyer L, Kim M, Shin J, Lee S, Yon D. Prenatal and infant exposure to antibiotics and subsequent risk of neuropsychiatric disorders in children: A nationwide birth cohort study in South Korea. Psychiatry Research 2024, 340: 116117. PMID: 39128166, DOI: 10.1016/j.psychres.2024.116117.Peer-Reviewed Original ResearchConceptsRisk of neuropsychiatric disordersNeuropsychiatric disordersAntibiotic exposureHazard ratioNationwide birth cohort studyHealth Screening CohortPostnatal lifeConfidence intervalsBirth cohort studyFollow-up durationDuration of prescriptionExposure to antibioticsEstimates of hazard ratiosLong-term riskScreening cohortChildhood neuropsychiatric disordersMaternal obesityPropensity score matchingAntibiotic prescriptionsPotential long-term risksCohort studyExposure statusIncreased riskBaseline variablesFamily factorsPrenatal opioid exposure and subsequent risk of neuropsychiatric disorders in children: nationwide birth cohort study in South Korea
Kang J, Kim H, Kim T, Lee H, Kim M, Lee S, Kim M, Koyanagi A, Smith L, Fond G, Boyer L, Rahmati M, Sánchez G, Dragioti E, Cortese S, Shin J, Yon D, Solmi M. Prenatal opioid exposure and subsequent risk of neuropsychiatric disorders in children: nationwide birth cohort study in South Korea. The BMJ 2024, 385: e077664. PMID: 38658035, PMCID: PMC11040462, DOI: 10.1136/bmj-2023-077664.Peer-Reviewed Original ResearchConceptsRisk of neuropsychiatric disordersPrenatal opioid exposureIncreased risk of neuropsychiatric disordersOpioid exposureNeuropsychiatric disordersComparison cohortNational Health Insurance Service of South KoreaOpioid doseNationwide birth cohort studyOpioid useNational Health Insurance ServiceDiagnosis of neuropsychiatric disordersFollow-upBirth cohort dataIncreased riskBirth cohort studyLong-term opioid useDate of deathData of pregnant womenDate of birthSeveral neuropsychiatric disordersMultiple subgroup analysesCohort studyHazard ratioFirst-trimester
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