2024
Construction and performance of a clinical prediction rule for ureteral stone without the use of race or ethnicity: A new STONE score
Moore C, Gross C, Hart L, Molinaro A, Rhodes D, Singh D, Baloescu C. Construction and performance of a clinical prediction rule for ureteral stone without the use of race or ethnicity: A new STONE score. Journal Of The American College Of Emergency Physicians Open 2024, 5: e13324. PMID: 39524039, PMCID: PMC11543628, DOI: 10.1002/emp2.13324.Peer-Reviewed Original ResearchClinical prediction ruleArea under the receiver operating characteristic curveSTONE scoreMultivariate logistic regressionUreteral stonesComputed tomographyPrediction ruleUncomplicated renal colicKidney stonesReceiver operating characteristic curveLogistic regressionNon-black raceDiagnosis of kidney stonesGross hematuriaMicroscopic hematuriaRenal colicPotential adverse effectsDiagnostic accuracyHematuriaClinical algorithmMale genderProspective dataClinical accuracyRetrospective dataCharacteristic curveRecommended guidelines for screening for underlying malignancy in extramammary Paget's disease based on anatomic subtype
Kibbi N, Owen J, Worley B, Alam M, Group E, Wang J, Harikumar V, Downing M, Aasi S, Aung P, Barker C, Bolotin D, Bordeaux J, Cartee T, Chandra S, Cho N, Choi J, Chung K, Cliby W, Dorigo O, Eisen D, Fujisawa Y, Golda N, Halfdanarson T, Iavazzo C, Jiang S, John E, Kanitakis J, Keimig E, Khan A, Linos E, Kim J, Kuzel T, Lawrence N, Leitao M, MacLean A, Maher I, Mittal B, Nehal K, Ozog D, Pettaway C, Rajan N, Ross J, Rossi A, Servaes S, Solomon M, Thomas V, Tolia M, Voelzke B, Waldman A, Wong M, Zhou Y, Brackett A, Poon E, Ahmed A. Recommended guidelines for screening for underlying malignancy in extramammary Paget's disease based on anatomic subtype. Journal Of The American Academy Of Dermatology 2024, 92: 261-268. PMID: 39401611, DOI: 10.1016/j.jaad.2024.07.1531.Peer-Reviewed Original ResearchExtramammary Paget's diseaseSecondary extramammary Paget's diseaseVulvar extramammary Paget diseasePerianal extramammary Paget's diseaseUrine cytologyAnatomic subtypesComputed tomographyPaget's diseaseProstate-specific antigen testingHigh-risk featuresOrgan-specific testsMultidisciplinary expert panelUnderlying malignancySystematic follow-upFollow-upAdenocarcinomaAntigen testAnatomical locationInclusion criteriaCytologyRetrospective dataScreening testSubtypesScreening algorithmRecommendation statementsMedicare volume and reimbursement trends in lingual and hyoid procedures for obstructive sleep apnea
Torabi S, Tsang C, Patel R, Nguyen T, Manes R, Kuan E, Trask D. Medicare volume and reimbursement trends in lingual and hyoid procedures for obstructive sleep apnea. American Journal Of Otolaryngology 2024, 45: 104361. PMID: 38729015, DOI: 10.1016/j.amjoto.2024.104361.Peer-Reviewed Original Research
2023
An Ensemble Machine Learning Model Using Gradient Boosting Identifies Patients with Disease Progression in Newly Diagnosed Multiple Myeloma
Williams L, Khosravi B, Velimirovic M, Khouri J, Raza S, Mazzoni S, Samaras C, Awada H, Dima D, Valent J, Anwer F. An Ensemble Machine Learning Model Using Gradient Boosting Identifies Patients with Disease Progression in Newly Diagnosed Multiple Myeloma. Blood 2023, 142: 1990. DOI: 10.1182/blood-2023-188762.Peer-Reviewed Original ResearchProgression free survivalMultiple myeloma patientsTreatment selectionFree survivalMyeloma patientsSurvival outcomesMultiple myelomaFrontline autologous stem cell transplantationDisease progressionProgression free survival valuesAutologous stem cell transplantationMedian progression free survivalNewly diagnosed multiple myelomaPrognostic modelSurvival analysisRetrospective dataStem cell transplantationFirst line treatmentDepth of responseDiagnosed multiple myelomaLog-rank testRandomized controlled clinical trialTime of diagnosisPatient related factorsNon-progressive cases
2022
A machine learning approach for predicting complications in descending and thoracoabdominal aortic aneurysms
Ostberg NP, Zafar MA, Mukherjee SK, Ziganshin BA, Elefteriades JA. A machine learning approach for predicting complications in descending and thoracoabdominal aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2022, 166: 1011-1020.e3. PMID: 35120761, DOI: 10.1016/j.jtcvs.2021.12.045.Peer-Reviewed Original ResearchConceptsType B dissectionThoracoabdominal aortic aneurysmsB dissectionCause mortalityAortic aneurysmReceiver operator curveAortic diameterOperator curveInitial patient encounterOccurrence of dissectionSurgical intervention criteriaMean followPatient sexMyocardial infarctionPatient encountersRetrospective dataEnd pointPatientsAneurysmsDissectionMortalityRisk predictionComplicationsIntervention criteriaRupture
2021
Teleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury.
Matiello M, Turner A, Estrada J, Whitney C, Kitch B, Lee P, Girkar U, Palacios R, Singla P, Schwamm L. Teleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury. Neurology 2021, 96: e1999-e2005. PMID: 33637632, DOI: 10.1212/wnl.0000000000011751.Peer-Reviewed Original ResearchConceptsIntensive care unitOrgan donorsNeurologic criteriaSevere neurologic damageSevere neurologic deficitsSevere neurologic injuryProportion of patientsDemographic informationPatient demographic informationPotential organ donorsDetermination of prognosisNumber of referralsProportion of donorsTeleneurology consultationsNeurologic deficitsNeurologic injuryMedian timeNeurologic damageCare unitComatose patientsCardiac arrestPatientsRetrospective dataConsultsOrgan donation
2020
Use of Provider Scorecards to Improve Early Postoperative Recovery—Initial Implementation Study
Khadge SD, Tanella A, Mtuke F, Deiner S, Hyman JB. Use of Provider Scorecards to Improve Early Postoperative Recovery—Initial Implementation Study. Journal For Healthcare Quality 2020, 43: 240-248. PMID: 33306521, DOI: 10.1097/jhq.0000000000000289.Peer-Reviewed Original ResearchConceptsLarge tertiary care academic centerTertiary care academic centerSevere postoperative painHealthy adult patientsImmediate postoperative recoveryIntraoperative anesthetic techniquePatient-centered measuresQuality of recoveryImplementation studyAmbulatory surgery casesPostoperative opioidsNonopioid analgesicsPostoperative painAdult patientsPostoperative recoveryGeneral anesthesiaAnesthetic techniqueSurgery casesAcademic centersRetrospective dataAnesthesiologistsRegional blocksSurgical specialtiesRecovery timeAntiemeticsSchool absenteeism as a potential proxy of functionality in pediatric patients with somatic symptom and related disorders
Vassilopoulos A, Poulopoulos N, Ibeziako P. School absenteeism as a potential proxy of functionality in pediatric patients with somatic symptom and related disorders. Clinical Child Psychology And Psychiatry 2020, 26: 342-354. PMID: 33287565, DOI: 10.1177/1359104520978462.Peer-Reviewed Original ResearchConceptsSchool absenteeismRelated disordersSomatic symptomsNormal school attendanceFunctional disability scorePsychiatry consultation servicePsychotropic medication useDisability scoresMedication usePediatric patientsClinical visitsFunctional disabilityPediatric hospitalPsychiatric carePatientsRetrospective dataSuicidal ideationCaregiver reportsHigher somatizationConsultation serviceSingle questionHigh rateSymptomsDisordersSchool functioningA Preliminary Simulation Study of Dose-Guided Adaptive Radiotherapy Based on Halcyon MV Cone-Beam CT Images With Retrospective Data From a Phase II Clinical Trial
Huang Y, Wang H, Li C, Hu Q, Liu H, Deng J, Li W, Wang R, Wu H, Zhang Y. A Preliminary Simulation Study of Dose-Guided Adaptive Radiotherapy Based on Halcyon MV Cone-Beam CT Images With Retrospective Data From a Phase II Clinical Trial. Frontiers In Oncology 2020, 10: 574889. PMID: 33134173, PMCID: PMC7550711, DOI: 10.3389/fonc.2020.574889.Peer-Reviewed Original ResearchPhase II clinical trialEvaluation patientsClinical trialsAnatomic changesAdaptive radiotherapyPlanning CTPreliminary clinical dataMVCBCT imagesCone-beam CT imagesTarget dose coverageDeformable image registrationClinical dataDose coverageCT imagesPatientsTarget underdosageFractional doseRetrospective dataTumor siteAdaptive plansDoseCTTarget coverageLocal gamma analysisTrialsMedical marijuana certification for patients with sickle cell disease: a report of a single center experience
Curtis SA, Lew D, Spodick J, Hendrickson JE, Minniti CP, Roberts JD. Medical marijuana certification for patients with sickle cell disease: a report of a single center experience. Blood Advances 2020, 4: 3814-3821. PMID: 32790846, PMCID: PMC7448584, DOI: 10.1182/bloodadvances.2020002325.Peer-Reviewed Original ResearchConceptsOpioid useMedical marijuanaSickle cell disease (SCD) reportBaseline opioid useSingle-center experienceHealth care utilizationSickle cell diseaseOpioid utilizationClinical characteristicsMost patientsCenter experienceCare utilizationSCD patientsInpatient hospitalizationRandom patientsAdmission ratesCell diseasePatientsRetrospective dataDisease reportsStudy periodHealth careCannabis productsCannabisEdible cannabis products
2018
Synergism between diabetes and human immunodeficiency virus in increasing the risk of tuberculosis
Sinha P, Moll AP, Brooks RP, Deng YH, Shenoi SV. Synergism between diabetes and human immunodeficiency virus in increasing the risk of tuberculosis. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 793-799. PMID: 29914606, PMCID: PMC6050202, DOI: 10.5588/ijtld.17.0936.Peer-Reviewed Original ResearchConceptsRisk of tuberculosisDiabetes mellitusTB symptomsOdds ratioHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionHuman immunodeficiency virusCommunity health screeningCross-sectional studyCommunity health projectsActive tuberculosisHIV infectionHIV positivityPrimary outcomeImmunodeficiency virusScreening servicesHealth screeningCongregate settingsVirus infectionResource-limited regionsMultiplicative scaleHIVMultivariate analysisRetrospective dataTuberculosis
2017
Trans-Sulcal Endoport-Assisted Evacuation of Supratentorial Intracerebral Hemorrhage: Initial Single-Institution Experience Compared to Matched Medically Managed Patients and Effect on 30-Day Mortality.
Sujijantarat N, Tecle N, Pierson M, Urquiaga J, Quadri N, Ashour A, Khan M, Buchanan P, Kumar A, Feen E, Coppens J. Trans-Sulcal Endoport-Assisted Evacuation of Supratentorial Intracerebral Hemorrhage: Initial Single-Institution Experience Compared to Matched Medically Managed Patients and Effect on 30-Day Mortality. Operative Neurosurgery 2017, 14: 524-531. PMID: 28973545, DOI: 10.1093/ons/opx161.Peer-Reviewed Original ResearchConceptsSupratentorial intracerebral hemorrhageIntracerebral hemorrhageSurgical cohortPresent cohortInitial Glasgow Coma Scale scoreInitial single-institution experienceGlasgow Coma Scale scoreSingle institution experienceMean volume reductionHospital mortalityPostoperative GCSPreoperative GCSClot evacuationSingle surgeonSurgical managementLarge trialsConventional craniotomyHemorrhage volumeMedical cohortInvasive techniquesPatientsScale scoreRetrospective dataCohortMedical controlA randomized phase II pilot study prospectively evaluating treatment for patients based on ERCC1 for advanced/ metastatic esophageal, gastric, or gastroesophageal junction cancer: SWOG S1201.
Iqbal S, McDonough S, Lenz H, Ilson D, Burtness B, Nangia C, Barzi A, Schneider C, Liu J, Dotan E, Guthrie K, Hochster H. A randomized phase II pilot study prospectively evaluating treatment for patients based on ERCC1 for advanced/ metastatic esophageal, gastric, or gastroesophageal junction cancer: SWOG S1201. Journal Of Clinical Oncology 2017, 35: 4009-4009. DOI: 10.1200/jco.2017.35.15_suppl.4009.Peer-Reviewed Original ResearchAdvanced esophagogastric cancerERCC1 levelsRandomized phase II pilot studyRandomized phase II studyPhase II pilot studyHigh ERCC1 levelsPhase II studyHER2-negative patientsGastroesophageal junction cancerDifferential treatment effectsMetastatic esophagealEsophagogastric cancerII studyJunction cancerNegative patientsPS 0Superior PFSERCC1 expressionTx groupFOLFOXPlatinum sensitivityRetrospective dataPFSHigh subgroupPilot study
2016
Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis
Wilcox CM, Sandhu BS, Singh V, Gelrud A, Abberbock JN, Sherman S, Cote GA, Al-Kaade S, Anderson MA, Gardner TB, Lewis MD, Forsmark CE, Guda NM, Romagnuolo J, Baillie J, Amann ST, Muniraj T, Tang G, Conwell DL, Banks PA, Brand RE, Slivka A, Whitcomb D, Yadav D. Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis. The American Journal Of Gastroenterology 2016, 111: 1488. PMID: 27527745, PMCID: PMC6196097, DOI: 10.1038/ajg.2016.316.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAgedAtrophyBlack or African AmericanCalcinosisCommon Bile Duct DiseasesConstriction, PathologicExocrine Pancreatic InsufficiencyFemaleHumansMaleMiddle AgedPain MeasurementPancreasPancreatic DiseasesPancreatic DuctsPancreatitis, AlcoholicPancreatitis, ChronicPrevalenceProspective StudiesRisk FactorsSex FactorsSmokingTime FactorsWhite PeopleYoung AdultConceptsChronic pancreatitisBlack patientsClinical profileDuration of CPNorth American Pancreatitis StudiesDuration of diseaseAlcoholic chronic pancreatitisProgression of pancreatitisRacial differencesPrior cholecystectomyPain characteristicsAlcohol etiologyCurrent smokersDisease durationSevere painEndoscopic treatmentWhite patientsRisk factorsPancreatic morphologyUS CentersEpidemiologic studiesPatientsAdvanced changesRetrospective dataDetailed questionnaire
2014
Development of the International Thymic Malignancy Interest Group International Database: An Unprecedented Resource for the Study of a Rare Group of Tumors
Huang J, Ahmad U, Antonicelli A, Catlin AC, Fang W, Gomez D, Loehrer P, Lucchi M, Marom E, Nicholson A, Ruffini E, Travis W, Van Schil P, Wakelee H, Yao X, Detterbeck F, Committee and Contributors O. Development of the International Thymic Malignancy Interest Group International Database: An Unprecedented Resource for the Study of a Rare Group of Tumors. Journal Of Thoracic Oncology 2014, 9: 1573-1578. PMID: 25521402, DOI: 10.1097/jto.0000000000000269.Peer-Reviewed Original ResearchConceptsInternational Thymic Malignancy Interest GroupThymic carcinomaThymic carcinoidMedian overall survivalSingle-institution seriesOverall survivalThymic malignanciesMyasthenia gravisRare tumorHistologic classificationSex distributionThymomaCarcinoidsCarcinomaRetrospective dataType B2Rare groupTumorsPatientsMalignancyGreater proportionInternational databasesYearsGravisGroupIs There a Role for Postmastectomy Radiation Therapy After Complete Pathologic Response to Neoadjuvant Chemotherapy?
Housri N, Haffty B. Is There a Role for Postmastectomy Radiation Therapy After Complete Pathologic Response to Neoadjuvant Chemotherapy? Current Breast Cancer Reports 2014, 6: 38-44. DOI: 10.1007/s12609-013-0134-8.Peer-Reviewed Original ResearchPathologic complete responsePostmastectomy radiationNeoadjuvant chemotherapySmall primary tumorsAdvanced breast cancerComplete pathologic responseNode-negative diseasePostmastectomy radiation therapyInitial clinical stageTime of mastectomyMulti-institutional trialPatterns of practiceAdvanced diseasePathologic responseComplete responseClinical stagePrimary tumorBreast cancerRadiation therapyRadiation indicationsLower riskPatientsRadiation oncologistsRetrospective dataChemotherapy
2011
Duration of exclusive breastfeeding; validity of retrospective assessment at nine months of age
Agampodi SB, Fernando S, Dharmaratne SD, Agampodi TC. Duration of exclusive breastfeeding; validity of retrospective assessment at nine months of age. BMC Pediatrics 2011, 11: 80. PMID: 21917175, PMCID: PMC3189116, DOI: 10.1186/1471-2431-11-80.Peer-Reviewed Original ResearchConceptsChild health development recordDuration of EBFExclusive breastfeedingRetrospective dataMaternal recallCohort studyEBF durationPregnancy recordsCessation of EBFMethodsA cohort studyMothers' recall dataRetrospective cohort studyProportion of infantsPublic health midwivesMother-infant pairsRecall dataMonths of ageBaseline data collectionStructured questionnaireMedian durationStudy cohortResultsA totalProspective dataSixth monthCase controlCMF revisited in the 21st century
Munzone E, Curigliano G, Burstein HJ, Winer EP, Goldhirsch A. CMF revisited in the 21st century. Annals Of Oncology 2011, 23: 305-311. PMID: 21715566, DOI: 10.1093/annonc/mdr309.Peer-Reviewed Original ResearchConceptsTriple-negative breast cancerBreast cancerClassical CMFOptimal chemotherapy backboneRecent retrospective dataUse of CMFTreatment of patientsTriple negative cellsPoly (ADP-ribose) polymerase (PARP) inhibitorsMechanism of actionAdjuvant CMFChemotherapy backboneAdjuvant treatmentRetrospective dataSpecific subgroupsPolymerase inhibitorsCancerTrue effectivenessPatientsCMFPlatinum compoundsDrugsTreatmentPast yearYears
2010
Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features
Conrado L, Hounie A, Diniz J, Fossaluza V, Torres A, Miguel E, Rivitti E. Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features. Journal Of The American Academy Of Dermatology 2010, 63: 235-243. PMID: 20561712, DOI: 10.1016/j.jaad.2009.09.017.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderCosmetic groupClinical characteristicsDermatologic patientsDermatologic treatmentPrevalence of BDDDysmorphic disorderGeneral dermatology patientsCross-sectional studyMental health professionalsCosmetic settingsDermatology settingsClinical featuresPrevious diagnosisDermatology patientsControl subjectsUniversity HospitalDermatologic settingDermatology groupCurrent prevalencePatientsControl groupHealth professionalsPsychiatric conditionsRetrospective data
2009
Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal
Weinberger AH, Maciejewski PK, McKee SA, Reutenauer EL, Mazure CM. Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal. American Journal On Addictions 2009, 18: 140-147. PMID: 19283566, PMCID: PMC2874459, DOI: 10.1080/10550490802544888.Peer-Reviewed Original ResearchConceptsAlcohol abuse/dependenceAbuse/dependenceMajor depressionWithdrawal symptomsPsychiatric statusSmoking relapsePanic disorderIndices of withdrawalStrong associationSmoking cessation interventionNational Comorbidity SurveyPosttraumatic stress disorderGender-specific effectsCessation interventionsNicotine withdrawalTobacco withdrawalRetrospective dataStress disorderLifetime alcoholLonger durationDepressionWithdrawalDisordersRelapseMultiple regression analysis
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