Z. Jimmy Zhou, PhD

On the cover: Motion and motion direction, illustrated here by the movement of six pool balls in a "starburst shot," are first detected in the retina by a synaptic circuit involving starburst amacrine cells (shown with Lucifer yellow filling). In this issue, Lee et al. show that starburst cells corelease ACh and GABA onto direction-selective ganglion cells at spatially symmetric cholinergic and spatially asymmetric GABAergic synapses, respectively. The cholinergic transmission facilitates motion detection, while the GABAergic transmission mediates direction selectivity.