Craig Crews, PhD
Biography
Research & Publications
News
Biography
Dr. Crews is the John C. Malone Professor of Molecular, Cellular and Developmental Biology and holds joint appointments in the departments of Chemistry and Pharmacology at Yale University. He graduated from the U.Virginia with a B.A. in Chemistry and received his Ph.D. from Harvard University in Biochemistry. Dr. Crews has a foothold in both the academic and biotech arenas; on the faculty at Yale since 1995, his laboratory has pioneered the use of small molecules to control intracellular protein levels. In 2003, he co-founded Proteolix, Inc., whose proteasome inhibitor, Kyprolis™ received FDA approval for the treatment of multiple myeloma. Since Proteolix’s purchase by Onyx Pharmaceuticals in 2009, Dr. Crews has focused on a new drug development technology, which served as the founding intellectual property for his latest New Haven-based biotech venture, Arvinas, Inc. Currently, Dr. Crews serves on several editorial boards and was Editor of Cell Chemical Biology (2008-2018). In addition, he has received numerous awards and honors, including the 2013 CURE Entrepreneur of the Year Award, 2014 Ehrlich Award for Medicinal Chemistry, 2015 Yale Cancer Center Translational Research Prize, a NIH R35 Outstanding Investigator Award (2015), the AACR Award for Chemistry in Cancer Research (2017), Khorana Prize from the Royal Society of Chemistry (2018), Pierre Fabre Award for Therapeutic Innovation (2018), the Pharmacia-ASPET Award for Experimental Therapeutics (2019), the Heinrich Wieland Prize (2020) and the Scheele Prize (2021). In 2019, he was named an American Cancer Society Professor and received the Connecticut Medal of Technology in 2022 as well as the Gabbay Award for Biotechnology and Medicine in 2023.
Education & Training
- Cancer Research Institute Postdoctoral FellowHarvard University (1995)
- PhDHarvard University, Biochemistry and Molecular Biology (1992)
- DAAD FellowUniversität Tübingen (1987)
- BAUniversity of Virginia, Chemistry (1986)
Activities
- Visiting Professor- University of KonstanzKonstanz, Baden-Wuerttemberg Region, Germany (2010-2013)Guest Professor, University of Konstanz
Honors & Recognition
Award | Awarding Organization | Date |
---|---|---|
Jacob and Louise Gabbay Award in Biotechnology and Medicine | Brandeis University | 2023 |
Bristol Myers Squibb Award for Enzyme Chemistry | American Chemical Society | 2023 |
Ivy Award | New Haven's annual Elm-Ivy Awards | 2023 |
Medal of Technology | Connecticut Academy of Science and Engineering | 2022 |
Irving Weinstein Foundation Distinguished Lectureship | American Association for Cancer Research (AACR) | 2022 |
Honorary Doctoral Degree (doctor rerum naturalium honoris causa) | Technical University Dortmund | 2021 |
Scheele Prize | Swedish Pharmaceutical Society | 2021 |
Award for Experimental Therapeutics | Pharmacia-ASPET | 2019 |
Research Professorship | American Cancer Society | 2019 |
Award for Therapeutic Innovation | Pierre Fabré | 2018 |
Khorana Prize | Royal Society of Chemistry | 2018 |
Award for Outstanding Achievement in Chemistry in Cancer Research | American Association for Cancer Research | 2017 |
Translational Research Prize | Yale Cancer Center | 2015 |
Outstanding Investigator Award (R35) | National Cancer Institute (NIH) | 2015 |
Connecticut Academy of Science and Engineering | 2015 | |
Fellow | American Association for the Advancement of Science (AAAS) | 2014 |
UCB-Ehrlich Award for Excellence in Medicinal Chemistry | European Federation of Medicinal Chemistry | 2014 |
Entrepreneur of the Year 2013 | Connecticut United for Research Excellence (CURE) | 2013 |
Senior Scholar in Aging | Ellison Medical Foundation | 2011 |
Guest Professor | University of Konstanz | 2010 |
Lewis B. Cullman Professor of MCDB | Yale University | 2010 |
Bessel Research Award | Alexander von Humboldt Foundation | 2006 |
Fellow | Royal Society of Chemistry (UK) | 2005 |
Arthur Greer Memorial Prize for Outstanding Junior Faculty Member in the Social or Natural Sciences | Yale University | 1999 |
CaPCURE Research Prize | Assoc. for the Cure of Cancer of the Prostate | 1996 |
New Investigator Award | Burroughs Wellcome Fund | 1996 |
New Investigator Award | Donaghue Foundation | 1996 |
Professional Service
Organization | Role | Date |
---|---|---|
PITCH (Program in Innovative Therapeutics for CT's Health) | Founder of a biotech accelerator focused on translating biological and biomedical discoveries into new biopharma ventures. | 2016 - Present |
ChemBioChem | Editorial Advisory Board | 2010 - Present |
Cell Chemical Biology (formerly Chemistry & Biology) | Editor | 2007 - Present |
NIH Chemistry and Biology Interface Training Grant | Principal Investigator | 2003 - Present |
Cell Chemical Biology (formerly Chemistry & Biology) | Editorial Board | 2001 - 2018 |
Molecular and Cellular Proteomics | Editorial Board | 2001 - 2009 |
Departments & Organizations
- Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS)
- Dean's Workshops
- Developmental Therapeutics
- Diabetes Research Center
- Molecular Cell Biology, Genetics and Development
- Secondary Faculty
- Yale Cancer Center
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale CTAP
- Yale Stem Cell Center
- Yale Ventures