Mehmet Sofuoglu MD, PhD

Professor of Psychiatry; Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)

Departments & Organizations

Office of Student ResearchCancer Prevention and ControlPsychiatry: Center for Nicotine and Tobacco Use Research at Yale (CENTURY); Psychotherapy Development Center; Specialized Center of Research (SCOR) on Sex and Gender Factors Affecting Women's Health; Stress & Addiction Clinical Research Program; Addictions, Division of; Yale Translational Center to Develop Gender-Sensitive Treatment for Tobacco Dependence; Yale Tobacco Center of Regulatory Science

Research Interests

Tobacco addiction; Cocaine addiction; Clinical trials; Human laboratory studies more...


  • M.D., Hacettepe University Faculty of Medicine, 1986
  • Ph.D., University of Minnesota, 1991

Selected Publications

  • Sofuoglu M, DeVito EE, Waters AJ, Carroll KM. Cognitive enhancement as a treatment for drug addictions. Neuropharmacology. 2013;64:452-63. PMCID: PMC 3445733.
  • Herman AI, Jatlow PI, Gelernter J, Listman JB, Sofuoglu M. COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers. The pharmacogenomics journal. 2013. PMCID: PMC3675163.
  • Sofuoglu M, Herman AI, Nadim H, Jatlow P. Rapid nicotine clearance is associated with greater reward and heart rate increases from intravenous nicotine. Neuropsychopharmacology 2012;37(6):1509-16, PMCID: 3327855.



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