2017
Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke
Lansberg MG, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai JP, Kim S, Nogueria RG, Jovin T, Devlin TG, Akhtar N, Yavagal DR, Haussen D, Dehkharghani S, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Investigators F. Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke. Annals Of Neurology 2017, 81: 849-856. PMID: 28486789, PMCID: PMC5521988, DOI: 10.1002/ana.24953.Peer-Reviewed Original ResearchConceptsBaseline CT perfusionSymptom onsetEndovascular therapyCT perfusionTomographic perfusionConsecutive acute stroke patientsSmall ischemic coreTarget mismatch profileMulticenter cohort studyAcute stroke patientsFavorable clinical responseSelection of patientsTarget mismatchRate of reperfusionCT perfusion studyMagnetic resonance imagingAnn NeurolCritical hypoperfusionEndovascular reperfusionClinical responseCohort studyIschemic strokeIschemic coreStroke patientsPatient population
2016
Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy
Federau C, Christensen S, Mlynash M, Tsai J, Kim S, Zaharchuk G, Inoue M, Straka M, Mishra NK, Kemp S, Lansberg MG, Albers GW. Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy. International Journal Of Stroke 2016, 12: 510-518. PMID: 27811306, DOI: 10.1177/1747493016677985.Peer-Reviewed Original ResearchMeSH KeywordsAgedBrainBrain IschemiaCohort StudiesEndovascular ProceduresFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedStrokeThrombectomyTime FactorsTreatment OutcomeConceptsInfarct lesion volumeFluid-attenuated inversion recoveryDiffusion-weighted imagingLesion volumeEndovascular thrombectomyInversion recoveryDay 5Fluid-attenuated inversion recovery lesionsPost-stroke onsetDegree of reperfusionStroke lesion volumeFluid-attenuated inversion recovery imagesInversion recovery imagesInfarct volumeInfarct growthStroke onsetSymptom onsetLesion growthPatientsRecovery imagesInterquartile rangeThrombectomyProcedure images
2015
Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue
Lansberg MG, Cereda CW, Mlynash M, Mishra NK, Inoue M, Kemp S, Christensen S, Straka M, Zaharchuk G, Marks MP, Bammer R, Albers GW, Saver J, Fayad P, Howard G, Tomsick. T, Jovin T, Wechsler L, DeCesare S, Thai D, Sherr A, Wilder M, Tricot A, Lutsep H, McDaneld L, Larsen D, Czartoski T, Keogh B, Malik A, Brown A, Bernstein R, Muskovich K, Chang C, Stern T, Warach S, Davis L, Fazekas F, Seifert-Held T. Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue. Neurology 2015, 85: 708-714. PMID: 26224727, PMCID: PMC4553034, DOI: 10.1212/wnl.0000000000001853.Peer-Reviewed Original ResearchConceptsGood functional outcomeEndovascular reperfusionFunctional outcomeSalvageable tissueLesion volumeLesion growthRandomized placebo-controlled trialModified Rankin Scale scorePerfusion Imaging EvaluationPerfusion lesion volumeTarget mismatch profilePlacebo-controlled trialRankin Scale scorePerfusion-diffusion mismatchSubgroup of patientsRadiologic outcomesCohort studyEndovascular therapyEarly followStroke patientsImaging evaluationReperfusionDay 90PatientsScale scoreReperfusion of Very Low Cerebral Blood Volume Lesion Predicts Parenchymal Hematoma After Endovascular Therapy
Mishra NK, Christensen S, Wouters A, Campbell BC, Straka M, Mlynash M, Kemp S, Cereda CW, Bammer R, Marks MP, Albers GW, Lansberg MG. Reperfusion of Very Low Cerebral Blood Volume Lesion Predicts Parenchymal Hematoma After Endovascular Therapy. Stroke 2015, 46: 1245-1249. PMID: 25828235, PMCID: PMC4414872, DOI: 10.1161/strokeaha.114.008171.Peer-Reviewed Original ResearchConceptsParenchymal hemorrhageIntravenous alteplaseEndovascular therapyBaseline imagingLesion volumeLow cerebral blood volumePerfusion Imaging EvaluationIschemic stroke patientsEndovascular reperfusion therapySingle independent predictorRoutine clinical practiceCerebral blood volumeMagnetic resonance imagingRegional reperfusionParenchymal hematomaReperfusion therapyIndependent predictorsEarly followRisk stratificationStroke patientsImaging evaluationNormal perfusionVLCBVBlood volumePatients
2011
Mutism and Amnesia following High-Voltage Electrical Injury: Psychogenic Symptomatology Triggered by Organic Dysfunction?
Mishra NK, Russmann H, Granziera C, Maeder P, Annoni JM. Mutism and Amnesia following High-Voltage Electrical Injury: Psychogenic Symptomatology Triggered by Organic Dysfunction? European Neurology 2011, 66: 229-234. PMID: 21952143, DOI: 10.1159/000330953.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmnesiaBrainElectric InjuriesFollow-Up StudiesHumansImage Processing, Computer-AssistedLanguage TestsMagnetic Resonance ImagingMaleMutismNeuropsychological TestsOxygenConceptsRetrograde amnesiaElectrical injuryNeuropsychological patternHigh-voltage electrical injuryTrauma 2 yearsDissociative symptomsMild head injuryDense retrograde amnesiaTranscranial magnetic stimulationLeft hemiparesisPatient's symptomsHead injuryInsular connectivityBrain lesionsOrganic dysfunctionSame patientMagnetic stimulationBrain impairmentAnatomoclinical correlationsRight prefrontal activitySymptomsInjuryMutismFunctional neuroimagingMemory evaluation
2008
Recurrent Wernicke's Aphasia: Migraine and Not Stroke!
Mishra NK, Rossetti AO, Ménétrey A, Carota A. Recurrent Wernicke's Aphasia: Migraine and Not Stroke! Headache The Journal Of Head And Face Pain 2008, 49: 765-768. PMID: 19456883, DOI: 10.1111/j.1526-4610.2008.01255.x.Peer-Reviewed Original Research
2007
Lifetime Basilar Migraine: A Pontine Syndrome?
Mishra NK, Cereda C, Carota A. Lifetime Basilar Migraine: A Pontine Syndrome? Headache The Journal Of Head And Face Pain 2007, 48: 476-478. PMID: 18081824, DOI: 10.1111/j.1526-4610.2007.01001.x.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overCalcinosisChronic DiseaseFemaleHumansMagnetic Resonance ImagingMigraine with AuraRaphe NucleiTomography, X-Ray Computed