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Nishant K. Mishra

Assistant Professor of Neurology; Affiliated Faculty, Yale Institute of Global Health



Dr. Mishra is a neurologist with a subspecialty interest in stroke management. He finished his medical school in December 2003 in India. Over the last two decades, he has pursued a range of clinical and research interests relevant to advancing the care of stroke patients. For example, his work on using IV tPA beyond recommendations in acute ischemic stroke significantly contributed to the field, informing physicians why several IV tPA exclusion criteria did not have a robust scientific basis.

At Yale, he is using his two-decades-long experience to lead a significant international effort: the International Post-Stroke Epilepsy Research Consortium (IPSERC). The consortium's goal is to prevent post-stroke epilepsy. He works closely with Dr. Patrick Kwan, Monash University, and a steering committee comprised Professors Jerome Engel Jr, Alon Friedman, Vijay Sharma, and Jacqueline French. He collaborates regionally and globally and leads several multinational collaborative projects to further the IPSERC's mission. He believes in promoting the younger generation of clinical neuroscientists, helping them succeed in academic medicine.

Relevant Publications:

  1. Misra S, Kasner SE, Dawson J, Tanaka T, Zhao Y, Zaveri HP, Eldem E, Vazquez J, Silva LS, Mohidat S, Hickman LB, Khan EI, Funaro MC, Nicolo JP, Mazumder R, Yasuda CL, Sunnerhagen KS, Ihara M, Ross JS, Liebeskind DS, Kwan P, Quinn TJ, Engel J Jr, Mishra NK. Outcomes in Patients With Poststroke Seizures: A Systematic Review and Meta-Analysis. JAMA Neurol. 2023 Sep 18; PubMed Central PMCID: PMC10507596.
  2. Misra S, Khan E, Lam TT, Mazumder R, Gururangan K, Hickman LB, Goswami V, Funaro MC, Eldem E, Sansing LH, Sico JJ, Quinn TJ, Liebeskind D, Montaner J, Kwan P, Mishra NK. The Common Pathways of Epileptogenesis in Patients With Epilepsy Post-Brain Injury: Findings From a Systematic Review and Meta-analysis. Neurology. 2023 Aug 7; PubMed PMID: 37550071.
  3. Misra S, Quinn T, Falcone G, Sharma V, de Havenon A, Zhao Y, Eldem E, French J, Yasuda C, Dawson J, Liebeskind D, Kwan P, Mishra N. Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review. European Journal of Neurology. 2023 March 23; 30(6):1791-1800. Available from: DOI: 10.1111/ene.15777
  4. Mishra NK, Engel J Jr, Liebeskind DS, Sharma VK, Hirsch LJ, Kasner SE, French JA, Devinsky O, Friedman A, Dawson J, Quinn TJ, Selim M, de Havenon A, Yasuda CL, Cendes F, Benninger F, Zaveri HP, Burneo JG, Srivastava P, Bhushan Singh M, Bhatia R, Vishnu VY, Bentes C, Ferro J, Weiss S, Sivaraju A, Kim JA, Galovic M, Gilmore EJ, Pitkänen A, Davis K, Sansing LH, Sheth KN, Paz JT, Singh A, Sheth S, Worrall BB, Grotta JC, Casillas-Espinos PM, Chen Z, Nicolo JP, Yan B, Kwan P. International Post Stroke Epilepsy Research Consortium (IPSERC): A consortium to accelerate discoveries in preventing epileptogenesis after stroke. Epilepsy Behav. 2022 Feb;127:108502. PubMed PMID: 34968775.

Education & Training

  • Vascular Neurology ACGME Fellow
    UCLA (2021)
  • NIH StrokeNet Fellow
    UCLA (Mentors: J. Saver, MD; D.S. Liebeskind, MD) (2021)
  • MD
    The University of The State of New York, By Conferral (2020)
  • Neurology Resident
    Mt. Sinai Hospital, Icahn School of Medicine at Mt. Sinai (2020)
  • Neurology Resident
    Tulane University (2018)
  • Internship
    Tulane University (2017)
  • ORISE Medical Scientist
    US Food and Drug Administration (2016)
  • Postdoctoral Fellow in Vascular Neurology
    Stanford University (Mentors: G. Albers, MD; M. Lansberg, MD) (2014)
  • PhD
    University of Glasgow, Medicine and Therapeutics (Mentor: K.R. Lees, MD, FRCP) (2012)
  • Visiting Researcher
    UT Houston (Mentors: J. Grotta, MD; Collaborator: TA Kent, MD; P Mandava, MD) (2011)
  • Visiting ESO researcher
    Karolinska University (Collaborator: N. Wahlgren, MD) (2009)
  • ESKAS Clinical Fellow
    University of Lausanne, CHUV (Mentors: A. Carota, MD; J.M. Annoni, MD) (2008)
  • MBBS
    Maharashtra University of Health Sciences, Nashik, India (2005)


  • Prevention of Post-Stroke Epileptogenesis
    University of California, Los Angeles; Los Angeles, CA 2023
    Frontiers in Neurology (UCLA)
  • Role Of Active Bilingualism In Promoting Cognitive Reserve And Resilience In Individuals At Risk Of Vascular Cognitive Impairment And Dementia
    Goa Velha, GA, India 2022
    International Symposium on Bilingualism and Cognition
  • Update on Contemporary Stroke Practice
    Invited talk to the CAPI. 2022
    CAPI - Journal Club
  • Stroke management during the COVID pandemic: An International Perspective
    Invited Speaker: Stroke management during the COVID pandemic: An International Perspective. Date: May 1st 2020. Audience: Indian Stroke Association. Chair: Shirish Hastak MD, Subhash Kaul MD 2020
    Stroke management during the COVID pandemic: An International Perspective
  • Use of iv alteplase beyond guidelines
    Mumbai, MH, India 2015
    Use of iv alteplase beyond guidelines
  • Perfusion Imaging to select stroke patients for recanalization therapy
    Mumbai, MH, India 2013
    Mumbai Stroke Society Meeting, Chaired by Dr. Bhim Singhal.
  • Outcomes After Thrombolysis Amongst Patients Aged greater than/=80 Years and Patients Having Diabetes or Previous Stroke: A Synopsis (Plenary Session)
    Barcelona, CT, Spain 2010
    Plenary Session, European Stroke Conference, Barcelona, 2010
  • Mismatch based delayed thrombolysis
    Mumbai, MH, India 2010
    Invited Talk, Grant Medical College, Mumbai. Chaired by Dr. Satish V Khadilkar.

Honors & Recognition

AwardAwarding OrganizationDate
StrokeNet Fellow, 2020-2021NIH/ UCLA2020
R25 NIH awardNational Institutes of Health2020
Leon Levy Foundation awardLeon Levy Foundation2020
Exceptional ReviewerAnnals of Internal Medicine2019
Exceptional ReviewerAnnals of Internal Medicine2017
ORISE awardOWH/ US FDA/ Oak Ridge Institute for Science and Education2015
Jim Gatheral Scholarship, UT Houston (Mentor: Dr. J Grotta)University of Glasgow, Scotland2011
Department to Department SITS-ISTR collaboration award, Karolinska University, SwedenEuropean Stroke Organisation2010
Overseas Research Studentship Award (ORSAS), University of Glasgow, Scotland, UKUK Secretary of State for Education and Science (ORSAS)2009
Roberts Travel AwardUniversity of Glasgow2009
Stipend award, University of Glasgow PhD StudentshipUniversity of Glasgow2008
Tuition award, University of Glasgow studentshipUniversity of Glasgow2008
Fellowship in Clinical Neurology (Stroke and Behavioral Neurology)Switzerland Government (ESKAS/ FCS award);Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne2006, 2008
Ratan Tata Trust Merit ScholarshipRatan Tata Trust, Government Medical College2002

Professional Service

United Kingdom Research and Innovation/ Medical Research Council (UKRI/MRC)Grant reviewer2023 - Present
American Indian Neurologist AssociationExecutive Committee Member; - Present
Cochrane Reviewer2023 - Present
All India Institute of Medical Sciences, New Delhi, IndiaExternal examiner of a Ph.D. in Neurology thesis; Ref: AIIMS/ExamSec/Ph.D/12-04/20222022 - Present
Association of Indian Neurologist AssociationMember2022 - Present
American Heart AssociationFAHA2022 - Present
Clinical Neurology and NeurosurgeryReviewer2022 - Present
Alzheimers Disease and Associated DisordersReviewer2022 - Present
BMJ Surgery, Interventions, and Health TechnologiesReviewer2022 - Present
Neurology (Green Journal)Editorial Board Member2022 - Present
International Post-Stroke Epilepsy Research Consortium (IPSERC)Convenor, IPSERC.2021 - Present
PLOS OneAcademic Editor2021 - Present
American Epilepsy SocietyMember2021 - Present
Epilepsy and BehaviorReviewer2021 - Present
Journal of Cerebral Blood Flow and MetabolismAd-Hoc Reviewer2020 - Present
Indian Stroke AssociationMember2020 - Present
Frontiers in Neurology (Stroke)Associate Editor (2019- present)2019 - Present
Frontiers NeurologyLaunched the following two research topics in my area of scientific interests: (1) Reperfusion Therapy for Acute Ischemic Stroke (2017-2019; Co-editor: Bruce Campbell) (2) Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke (2020-2021; Co-editors: Richard Leigh and Bruce Campbell).2017 - Present
Stroke JournalRecognized by the Editor, Dr. Marc fisher2017 - Present
BMJReviewer2016 - Present
Frontiers NeurologyAssociate Editor since 20192013 - Present
CMAJReviewer2013 - Present
Diabetes CareReviewer2013 - Present
Annals Internal MedicineReviewer2013 - Present
European Stroke OrganisationFellow of European Stroke Organization (FESO)2012 - Present
ADIS Drug EvaluationAlteplase: A review of its use in the management of Acute Ischemic Stroke. Co-reviewers: HP Adam, D Leys, S Lorenzano, and D Toni.2012
NeurocaseReviewer2012 - Present
BrainAd-Hoc reviewer2011 - Present
European Journal of NeurologyReviewer2011 - Present
Neurology JournalEditorial Board Member (2021-present) Ad-hoc reviewer (2006-2021)2010 - Present
Stroke JournalAd-hoc reviewer2006 - Present
World Stroke OrganisationMember2006 - Present

Departments & Organizations