Influence of Age on Outcome From Thrombolysis in Acute Stroke
Mishra NK, Diener HC, Lyden PD, Bluhmki E, Lees KR. Influence of Age on Outcome From Thrombolysis in Acute Stroke. Stroke 2010, 41: 2840-2848. PMID: 21030710, DOI: 10.1161/strokeaha.110.586206.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeHealth scale scoresControl subjectsIschemic strokeInfluence of ageScale scoreBaseline National InstitutesRankin Scale scoreNational InstituteLimited trial dataNeuroprotection trialsRankin scoreThrombolysis treatmentAcute strokeYounger patientsAge decilesPoor outcomeBaseline severityImproved outcomesPatientsHaenszel testTrial dataCochran-MantelThrombolysisLogistic regressionComparison of Outcomes Following Thrombolytic Therapy Among Patients With Prior Stroke and Diabetes in the Virtual International Stroke Trials Archive (VISTA)
Mishra NK, Davis SM, Kaste M, Lees KR, . Comparison of Outcomes Following Thrombolytic Therapy Among Patients With Prior Stroke and Diabetes in the Virtual International Stroke Trials Archive (VISTA). Diabetes Care 2010, 33: 2531-2537. PMID: 20843977, PMCID: PMC2992183, DOI: 10.2337/dc10-1125.Peer-Reviewed Original ResearchConceptsVirtual International Stroke Trials ArchivePrior strokeUse of alteplaseBaseline National InstitutesHealth Stroke ScaleProportional odds logistic regression analysisInfluence of diabetesInteraction of diabetesComparison of outcomesLogistic regression analysisConcomitant diabetesEligible patientsNeurological outcomeStroke ScaleIschemic strokeThrombolytic treatmentThrombolytic therapyThrombolysed patientsFunctional outcomeControl subjectsOutcome measuresPatientsDiabetesHaenszel testCochran-Mantel