2000
Ionic Mechanisms Underlying Repetitive High-Frequency Burst Firing in Supragranular Cortical Neurons
Brumberg J, Nowak L, McCormick D. Ionic Mechanisms Underlying Repetitive High-Frequency Burst Firing in Supragranular Cortical Neurons. Journal Of Neuroscience 2000, 20: 4829-4843. PMID: 10864940, PMCID: PMC6772270, DOI: 10.1523/jneurosci.20-13-04829.2000.Peer-Reviewed Original ResearchConceptsLayer II/III pyramidal neuronsHigh-frequency burst dischargesAction potential generationAction potentialsPyramidal neuronsCortical neuronsBurst dischargesHigh-frequency burst firingVisual cortical slicesAction potential burstsFirst action potentialBurst-firing modeHigh-frequency burstsPotential generationIonic mechanismsIntrinsic burstsCortical slicesLocal cortical networksBurst firingNeocortical neuronsIntracellular recordingsPostsynaptic neuronsATX IIQX-314Single spiking
1997
Modulation of spindle oscillations by acetylcholine, cholecystokinin and 1S,3R-ACPD in the ferret lateral geniculate and perigeniculate nuclei in vitro
Lee K, McCormick D. Modulation of spindle oscillations by acetylcholine, cholecystokinin and 1S,3R-ACPD in the ferret lateral geniculate and perigeniculate nuclei in vitro. Neuroscience 1997, 77: 335-350. PMID: 9472394, DOI: 10.1016/s0306-4522(96)00481-2.Peer-Reviewed Original ResearchConceptsSpindle wave generationInhibitory postsynaptic potentialsThalamocortical neuronsLocal applicationTonic dischargeSpindle wavesPostsynaptic potentialsPerigeniculate nucleusGlutamate metabotropic receptor agonistMetabotropic receptor agonistMembrane depolarizationEffects of neurotransmittersSlow-wave sleepPerigeniculate neuronsLeak potassium currentGABAergic cellsGABAergic neuronsLateral geniculateReceptor agonistTonic activityWave sleepPotassium currentThalamic networkACPDNeurons
1993
Control of firing mode of corticotectal and corticopontine layer V burst-generating neurons by norepinephrine, acetylcholine, and 1S,3R- ACPD
Wang Z, McCormick D. Control of firing mode of corticotectal and corticopontine layer V burst-generating neurons by norepinephrine, acetylcholine, and 1S,3R- ACPD. Journal Of Neuroscience 1993, 13: 2199-2216. PMID: 8386756, PMCID: PMC6576582, DOI: 10.1523/jneurosci.13-05-02199.1993.Peer-Reviewed Original ResearchConceptsIntracellular recordingsMetabotropic receptorsPyramidal cellsLayer V pyramidal cellsGlutamate metabotropic receptor agonistLayer V cellsMetabotropic receptor agonistApplication of norepinephrineAlpha-agonist phenylephrineBeta-antagonist propranololSingle spike activityMuscarinic antagonist scopolamineBeta-agonist isoprenalinePrimary visual cortexAction potential generationSingle-spike modeACh effectsMuscarinic subtypesNE responseInterburst frequencyMuscarinic agonistsReceptor agonistBath applicationPostsynaptic responsesAntagonist scopolamine