Functional and Ionic Properties of a Slow Afterhyperpolarization in Ferret Perigeniculate Neurons In Vitro
Kim U, Mccormick D. Functional and Ionic Properties of a Slow Afterhyperpolarization in Ferret Perigeniculate Neurons In Vitro. Journal Of Neurophysiology 1998, 80: 1222-1235. PMID: 9744934, DOI: 10.1152/jn.1998.80.3.1222.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnesthetics, LocalAnimalsApaminBicucullineCalciumCalcium Channel BlockersExcitatory Postsynaptic PotentialsFemaleFerretsGABA AntagonistsGamma-Aminobutyric AcidGeniculate BodiesLidocaineMaleNeuronsOmega-Conotoxin GVIAPeptidesPeriodicityPotassiumPotassium ChannelsSodiumTetraethylammoniumTetrodotoxinConceptsApplication of apaminSlow afterhyperpolarizationLow-threshold Ca2Perigeniculate neuronsPlateau potentialsBlock of Ca2Spindle wave generationMedium-duration afterhyperpolarizationGABAergic neuronsTonic dischargeFast afterhyperpolarizationPerigeniculate nucleusIntracellular recordingsAfterhyperpolarizationAction potentialsRefractory periodLocal applicationProlonged depolarizationRepetitive Ca2Spindle wavesReversal potentialNeuronsApaminMembrane conductanceActivationPeriodicity of Thalamic Spindle Waves Is Abolished by ZD7288,a Blocker of I h
Lüthi A, Bal T, McCormick D. Periodicity of Thalamic Spindle Waves Is Abolished by ZD7288,a Blocker of I h. Journal Of Neurophysiology 1998, 79: 3284-3289. PMID: 9636128, DOI: 10.1152/jn.1998.79.6.3284.Peer-Reviewed Original ResearchConceptsSpindle wavesHyperpolarization-activated cation current IhCurrent-clamp recordingsIntracellular recording techniquesBlock of IhVoltage-clamp recordingsRebound burstsThalamic activityRefractory periodPacemaker currentLocal applicationZD7288AfterdepolarizationsCurrent IhRecording techniquesRepetitive hyperpolarizationNetwork activityHyperpolarizationSlow rhythmicityFurther supportIHPeriodicity of Thalamic Synchronized Oscillations: the Role of Ca2+-Mediated Upregulation of Ih
Lüthi A, McCormick D. Periodicity of Thalamic Synchronized Oscillations: the Role of Ca2+-Mediated Upregulation of Ih. Neuron 1998, 20: 553-563. PMID: 9539128, DOI: 10.1016/s0896-6273(00)80994-0.Peer-Reviewed Original ResearchConceptsPersistent activationRefractory periodHyperpolarization-activated cation current IhNeural network oscillationsSynchronized network activityWave seizuresRole of Ca2Synchronized dischargesThalamocortical cellsThalamocortical networkElectrophysiological propertiesMediated UpregulationSpindle wavesCurrent IhConstituent neuronsNetwork oscillationsAbnormal patternsActivation curveTime courseNetwork activityUpregulationActivationCritical determinant