1984
Effects of lesions of cerebellar nuclei on conditioned behavioral and hippocampal neuronal responses
Clark G, McCormick D, Lavond D, Thompson R. Effects of lesions of cerebellar nuclei on conditioned behavioral and hippocampal neuronal responses. Brain Research 1984, 291: 125-136. PMID: 6697177, DOI: 10.1016/0006-8993(84)90658-9.Peer-Reviewed Original ResearchConceptsCerebellar nucleiNeuronal responsesUnilateral electrolytic lesionsHippocampal neuronal responsesEffects of lesionsIpsilateral sideContralateral sideControl animalsElectrolytic lesionsHippocampal responsesDeep nucleiLesionsLearning deficitsLeft sideRight sideNeural activityTrials of trainingComplete abolition
1982
Locus coeruleus lesions and resistance to extinction of a classically conditioned response: Involvement of the neocortex and hippocampus
McCormick D, Thompson R. Locus coeruleus lesions and resistance to extinction of a classically conditioned response: Involvement of the neocortex and hippocampus. Brain Research 1982, 245: 239-249. PMID: 7127072, DOI: 10.1016/0006-8993(82)90806-x.Peer-Reviewed Original ResearchConceptsDepletion of norepinephrineExtinction deficitNon-lesioned controlsBilateral electrolytic lesionsLocus coeruleus lesionsHippocampal norepinephrineLocus coeruleusNE depletionDopamine levelsHippocampal samplesElectrolytic lesionsDay 3Control groupNorepinephrineBrain regionsHypothalamus/Significant differencesThird groupUnpaired trainingLesionsNM responseUnpaired extinctionConditioned responseSignificant depletionAnimalsIpsilateral cerebellar lesions prevent learning of the classically conditioned nictitating membrane/eyelid response
Lincoln J, McCormick D, Thompson R. Ipsilateral cerebellar lesions prevent learning of the classically conditioned nictitating membrane/eyelid response. Brain Research 1982, 242: 190-193. PMID: 7104727, DOI: 10.1016/0006-8993(82)90510-8.Peer-Reviewed Original ResearchInitial localization of the memory trace for a basic form of learning.
McCormick D, Clark G, Lavond D, Thompson R. Initial localization of the memory trace for a basic form of learning. Proceedings Of The National Academy Of Sciences Of The United States Of America 1982, 79: 2731-2735. PMID: 6953427, PMCID: PMC346276, DOI: 10.1073/pnas.79.8.2731.Peer-Reviewed Original ResearchConceptsNeuronal unit activityEye contralateralReflex responsesIpsilateral cerebellumUnconditioned reflex responseNeuronal plasticityCerebellar lesionsElectrophysiological recordingsUnit activityLateral cerebellumCerebellumTraining trialsBehavioral responsesMarked contrastResponseMembrane responseContralateralLesions
1981
The engram found? Role of the cerebellum in classical conditioning of nictitating membrane and eyelid responses
Mccormick D, Lavond D, Clark G, Kettner R, Rising C, Thompson R. The engram found? Role of the cerebellum in classical conditioning of nictitating membrane and eyelid responses. Psychonomic Bulletin & Review 1981, 18: 103-105. DOI: 10.3758/bf03333573.Peer-Reviewed Original ResearchIpsilateral cerebellumEye contralateralEyelid responsesReflex responsesStereotaxic lesionsNeural unit activityUnconditioned reflex responseNeuronal plasticityCerebellar lesionsElectrophysiological recordingsUnit activityCerebellumLesionsNeural activityClassical conditioningLarger ablationsTraining trialsBehavioral responses