2000
Corticothalamic Inputs Control the Pattern of Activity Generated in Thalamocortical Networks
Blumenfeld H, McCormick D. Corticothalamic Inputs Control the Pattern of Activity Generated in Thalamocortical Networks. Journal Of Neuroscience 2000, 20: 5153-5162. PMID: 10864972, PMCID: PMC6772273, DOI: 10.1523/jneurosci.20-13-05153.2000.Peer-Reviewed Original ResearchConceptsParoxysmal oscillationsThalamic burstsReceptor antagonist CGP 35348Corticothalamic tractsSpindle wavesAntagonist CGP 35348Receptor antagonist picrotoxinSlow-wave sleepHz oscillationsHigh-frequency burstsNormal action potentialPerigeniculate neuronsCGP 35348Antagonist picrotoxinSlow IPSPCorticothalamic inputsFast IPSPsThalamocortical neuronsCortical influencesAbsence seizuresBurst firingCortical neuronsCortical firingThalamocortical networkCorticothalamic networks
1997
SLEEP AND AROUSAL: Thalamocortical Mechanisms
McCormick D, Bal T. SLEEP AND AROUSAL: Thalamocortical Mechanisms. Annual Review Of Neuroscience 1997, 20: 185-215. PMID: 9056712, DOI: 10.1146/annurev.neuro.20.1.185.Peer-Reviewed Original ResearchConceptsThalamic reticular neuronsReticular neuronsCerebral cortex resultsCortical pyramidal cellsIntrinsic membrane propertiesBasal forebrainEnhanced excitabilityBrain stemMovement sleepAbsence seizuresTonic activityPyramidal cellsThalamocortical activitySleep rhythmsAnatomical interconnectionsCortex resultsThalamocortical mechanismsDifferent neurotransmittersParoxysmal eventsSpindle wavesRhythmic activitySpecific alterationsSleepSensory processingSlow waves
1996
What Stops Synchronized Thalamocortical Oscillations?
Bal T, McCormick D. What Stops Synchronized Thalamocortical Oscillations? Neuron 1996, 17: 297-308. PMID: 8780653, DOI: 10.1016/s0896-6273(00)80161-0.Peer-Reviewed Original Research
1994
From Cellular to Network Mechanisms of a Thalamic Synchronized Oscillation
Bal T, von Krosigk M, McCormick D. From Cellular to Network Mechanisms of a Thalamic Synchronized Oscillation. Research And Perspectives In Neurosciences 1994, 129-143. DOI: 10.1007/978-3-642-85148-3_8.Peer-Reviewed Original ResearchSpindle wavesDorsal lateral geniculate nucleusFerret dorsal lateral geniculate nucleusIntracellular recording techniquesLateral geniculate nucleusGeneralized epilepsyAbsence seizuresGABAA receptorsSlice preparationGeniculate nucleusPharmacological blockSynaptic networksNeural circuitsRecording techniquesCortical systemsPhysiological basisIonic conductancesEpilepsySeizuresLGNdSynchronized oscillations
1993
Cellular Mechanisms of a Synchronized Oscillation in the Thalamus
von M, Bal T, McCormick D. Cellular Mechanisms of a Synchronized Oscillation in the Thalamus. Science 1993, 261: 361-364. PMID: 8392750, DOI: 10.1126/science.8392750.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsSpindle wavesPostsynaptic potentialsAbsence seizuresRelay cellsFerret lateral geniculate nucleusRhythmic population activityGABAB inhibitory postsynaptic potentialsReceptor-mediated inhibitionSeizure-like activityLateral geniculate nucleusGABAB receptorsRebound burstsGABAB antagonistRelay neuronsPerigeniculate nucleusGeniculate nucleusPharmacological blockNeuronal activityCortical systemsCellular mechanismsPopulation activitySeizuresCellsThalamus