Karthik Murugiah, MBBS, MHS
Assistant Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2025
Mechanical Circulatory Support in Acute Myocardial Infarction–Cardiogenic Shock 2025 Acute Coronary Syndrome Guideline in Context
Murugiah K, McDonagh T, Cohen D, Dhruva S. Mechanical Circulatory Support in Acute Myocardial Infarction–Cardiogenic Shock 2025 Acute Coronary Syndrome Guideline in Context. Journal Of The American College Of Cardiology 2025, 85: 2103-2106. PMID: 40467139, DOI: 10.1016/j.jacc.2025.04.025.Peer-Reviewed Original ResearchHealthcare Expenditure on Atrial Fibrillation in the United States The Medical Expenditure Panel Survey 2016 to 2021
See C, Grubman S, Shah N, Hu J, Nanna M, Freeman J, Murugiah K. Healthcare Expenditure on Atrial Fibrillation in the United States The Medical Expenditure Panel Survey 2016 to 2021. JACC Advances 2025, 4: 101716. PMID: 40286372, PMCID: PMC12103078, DOI: 10.1016/j.jacadv.2025.101716.Peer-Reviewed Original ResearchMedical Expenditure Panel SurveyHealthcare expendituresInternational Classification of Disease-10 codesNationally representative assessmentTotal healthcare expendituresPoor income levelsPanel SurveyHigher expendituresIncreased healthcare expendituresAssociated with higher expendituresChronic obstructive pulmonary diseaseModified Charlson Comorbidity IndexObstructive pulmonary diseaseInpatient visitsInternational ClassificationType 2 diabetes mellitusSurvey yearCharlson Comorbidity IndexAtherosclerotic cardiovascular diseaseUnited StatesIdentifying individualsCardiovascular diseaseGamma regression modelRegression modelsRepresentative assessmentRecent Trends in Aspirin Use for Cardiovascular Disease Prevention in the United States, 2015 to 2023
Murugiah K, See C, Huang C. Recent Trends in Aspirin Use for Cardiovascular Disease Prevention in the United States, 2015 to 2023. JACC Advances 2025, 4: 101699. PMID: 40243986, DOI: 10.1016/j.jacadv.2025.101699.Peer-Reviewed Original ResearchCHARACTERIZATION OF POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME IN LONG COVID: A CROSS-SECTIONAL STUDY AND A MACHINE LEARNING MODEL
AL Mouslmani M, Sawano M, Arun A, Wu Y, Shah R, Kaleem S, Zhou T, Murugiah K, Lu Y, Herrin J, Taub P, Peixoto A, Krumholz H. CHARACTERIZATION OF POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME IN LONG COVID: A CROSS-SECTIONAL STUDY AND A MACHINE LEARNING MODEL. Journal Of The American College Of Cardiology 2025, 85: 2720. DOI: 10.1016/s0735-1097(25)03204-8.Peer-Reviewed Original Research
2024
Association of door-to-balloon time and one-year outcomes in hospital survivors of ST-elevation myocardial infarction
Sawano M, Kohsaka S, Murugiah K, Ishii H, Yamaji K, Takahashi J, Ozaki K, Amano T, Kozuma K. Association of door-to-balloon time and one-year outcomes in hospital survivors of ST-elevation myocardial infarction. Journal Of Cardiology 2024, 85: 98-99. PMID: 38964710, DOI: 10.1016/j.jjcc.2024.06.009.Peer-Reviewed Original ResearchDoor-to-balloon timeST-elevation myocardial infarctionAdjusted hazard ratiosSurvivors of ST-elevation myocardial infarctionMyocardial infarctionPatients aged <Specific patient subgroupsAdverse cardiovascular eventsOne-year outcomesAcute coronary eventsRevascularization historyMACE riskCardiogenic shockCoronary revascularizationOutcomes RegistryCardiovascular eventsHospital survivorsPatient subgroupsCardiac arrestSubgroup analysisCardiovascular outcomesHazard ratioHigher comorbiditiesCoronary eventsPrimary preventionHeterogeneity in the Prognosis of Acute Kidney Injury Following Percutaneous Coronary Intervention
Hu J, Murugiah K, Xin X, Sawano M, Lu Y, Wilson F, Masoudi F, Messenger J, Krumholz H, Huang C. Heterogeneity in the Prognosis of Acute Kidney Injury Following Percutaneous Coronary Intervention. Journal Of The American Heart Association 2024, 13: e033649. PMID: 38390832, PMCID: PMC10944032, DOI: 10.1161/jaha.123.033649.Peer-Reviewed Original Research
2023
Wireless pulmonary artery sensor implantation in a unilateral lung transplant recipient
Kelly R, Bae J, Mansour A, Nagpal S, Hahn S, Murugiah K. Wireless pulmonary artery sensor implantation in a unilateral lung transplant recipient. Journal Of Cardiology Cases 2023, 28: 216-220. PMID: 38024115, PMCID: PMC10658300, DOI: 10.1016/j.jccase.2023.08.004.Peer-Reviewed Case Reports and Technical NotesPulmonary artery pressure monitorLung transplant recipientsLung transplantationCardioMEMS deviceTransplant recipientsHeart failurePressure monitorPulmonary artery injuryPulmonary artery pressureDevice-related complicationsSelective pulmonary angiographyFirst such caseArtery pressureVentricular failureArtery injuryHemodynamic managementPost transplantationHemodynamic assessmentPulmonary angiographyRight PAInvasive monitoringTransplantationSignificant tortuositySmall caliberTwo yearsPatterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019
See C, Wheelock K, Caraballo C, Khera R, Annapureddy A, Mahajan S, Lu Y, Krumholz H, Murugiah K. Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019. American Journal Of Medicine Open 2023, 10: 100048. PMID: 38213879, PMCID: PMC10783702, DOI: 10.1016/j.ajmo.2023.100048.Peer-Reviewed Original ResearchDigoxin prescriptionDigoxin useNew heart failure therapiesGeneral medicine physiciansHeart failure therapyMedicare Part D dataPart D dataDigoxin prescribingFailure therapyPrescriber characteristicsMedicine physiciansMedicare beneficiariesPrescribersLikely maleLogistic regressionDigoxinNew prescribersPrescriptionRecent dataCardiologySex Difference in Outcomes of Acute Myocardial Infarction in Young Patients
Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNoncardiac hospitalizationsSubdistribution HRYounger patientsMyocardial infarctionSex differencesYoung womenCause-specific hospitalizationsCause of hospitalizationWorse health statusSignificant sex disparityNoncardiovascular hospitalizationsVIRGO StudyIndex episodeAdverse outcomesIncidence rateHospitalizationHigh riskSex disparitiesHealth statusPatientsU.S. hospitalsWomenInfarctionOutcomesInvasive Pulmonary Angiogram Performance and Interpretation in the Diagnosis of Pulmonary Thromboembolic Disease
Bae J, Murugiah K. Invasive Pulmonary Angiogram Performance and Interpretation in the Diagnosis of Pulmonary Thromboembolic Disease. Interventional Cardiology Clinics 2023, 12: 299-307. PMID: 37290835, PMCID: PMC10693920, DOI: 10.1016/j.iccl.2023.03.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInvasive pulmonary angiographyPulmonary thromboembolic diseasePulmonary angiographyThromboembolic diseaseGold standard diagnostic testSelective pulmonary angiographyOptimal patient positioningStandard diagnostic testNoninvasive imaging modalityPulmonary vascular anatomyAngiographic patternsCatheter selectionVascular accessVascular anatomyArterial conditionsAngiographyDiagnostic testsPatient positioningImaging modalitiesDisease
Academic Achievements & Community Involvement
Teaching & Mentoring
Mentoring
Tom Shin
Postdoc2023 - PresentClaudia See
Medical student2022 - 2024Ju-Young Bae
Postdoc2021 - 2024
Clinical Care
Overview
Karthik Murugiah, MBBS (a medical degree awarded in several countries outside of the U.S.), is an interventional cardiologist and specializes in treating coronary artery disease, heart attacks, heart failure, pulmonary hypertension, and other conditions.
Dr. Murugiah says he was drawn to cardiology because of its promise and potential. “Cardiology is an extremely fast-paced specialty with a large and rigorous evidence base and a wide gamut of treatments,” he says. “This makes being a cardiologist especially gratifying. I love talking to patients, hearing their stories, helping them understand their illness and make decisions about their health. We can deliver cutting-edge treatments for cardiac conditions to every patient in line with the latest medical evidence.”
The best part of his job, he says, is helping patients recover from life-threatening cardiac conditions and helping them manage chronic cardiac problems, so that they can enjoy their lives to the fullest extent possible.
Recognizing that patients often feel anxious about medical procedures, Dr. Murugiah says he makes sure they have a clear understanding of the treatment and what to expect during and after it. “I emphasize to patients that we will always have their best interest in mind with every decision we take or treatments we recommend,” he says. “I also tell patients undergoing procedures to lean on the experience of my catheterization lab team and I.”
An active researcher, Dr. Murugiah focuses on harnessing electronic health records and other large datasets to develop prediction models and evaluate changes in health and health care delivery to answer important questions in cardiology care in the U.S. and globally.
Clinical Specialties
Fact Sheets
Heart Attack (Myocardial Infarction)
Learn More on Yale MedicinePulmonary Edema
Learn More on Yale MedicineCoronary Artery Disease (CAD)
Learn More on Yale MedicineBlood Clots in Veins, Heart and Lungs
Learn More on Yale Medicine
Board Certifications
Interventional Cardiology
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
Cardiovascular Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2018
Yale Medicine News
News
News
- July 02, 2024
Yale Faculty Members Named to JACC Editorial Board
- April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions
- February 01, 2023
2023 American College of Cardiology late-breaking clinical trials and abstracts from Yale
- January 18, 2023
Inpatient blood draws are often performed during sleep hours, Yale study finds
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195 CHURCH ST
NEW HAVEN, CT 06510
United States
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