2024
Cross-Modality Translation with Generative Adversarial Networks to Unveil Alzheimer’s Disease Biomarkers
Hassanzadeh R, Abrol A, Hassanzadeh H, Calhoun V. Cross-Modality Translation with Generative Adversarial Networks to Unveil Alzheimer’s Disease Biomarkers. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2024, 00: 1-4. PMID: 40039975, DOI: 10.1109/embc53108.2024.10781737.Peer-Reviewed Original ResearchConceptsFunctional network connectivityGenerative adversarial networkStructural similarity index measureT1-weighted structural magnetic resonance imaging dataAdversarial networkStructural magnetic resonance imaging dataIncreased functional connectivityMagnetic resonance imaging dataSimilarity index measureCross-modal transformerCross-modal translationPatterns of atrophyAlzheimer's diseaseFunctional connectivityReduced connectivityMotor-visualTemporal regionsWeak supervisionAlzheimer's disease biomarkersControl networkCycle-GANCross-modalAlzheimer patientsContext of Alzheimer's diseaseGeneration approachAssociations Between Neighborhood Resources and Youths’ Response to Reward Omission in a Task Modeling Negatively Biased Environments
Brown B, Nguyen L, Morales I, Cardinale E, Tseng W, McKay C, Kircanski K, Brotman M, Pine D, Leibenluft E, Linke J. Associations Between Neighborhood Resources and Youths’ Response to Reward Omission in a Task Modeling Negatively Biased Environments. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024, 64: 463-474. PMID: 38763411, DOI: 10.1016/j.jaac.2024.05.011.Peer-Reviewed Original ResearchChildhood Opportunity IndexPaper self-identifiesNeighborhood resourcesAbstractText Label="DIVERSITY &Functional magnetic resonance imagingAbstractText Label="METHOD" NlmCategory="METHODS">Ethnic groupsReward omissionBlocked goalsNeurobiological levelMood disordersNeurodevelopmental trajectoriesLocal processing modeMental healthReduced connectivityDiverse sampleInvestigate associationsControl networkNeighborhood featuresQuantify accessProvincial hubsPromote sexRewardOpportunity IndexMagnetic resonance imaging
2023
Creativity at rest: Exploring functional network connectivity of creative experts
Orwig W, Setton R, Diez I, Bueichekú E, Meyer M, Tamir D, Sepulcre J, Schacter D. Creativity at rest: Exploring functional network connectivity of creative experts. Network Neuroscience 2023, 7: 1022-1033. PMID: 37781148, PMCID: PMC10473280, DOI: 10.1162/netn_a_00317.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingFunctional connectivityReduced connectivityAssociated with creative abilityReplicate prior findingsVisual cortexBrain network organizationStudies of functional connectivityFunctional brain connectivityLateral visual cortexFunctional network connectivityNeuroscience of creativityComplex brain processesNeuroimaging studiesGeneration of novel ideasBrain processesBrain connectivityConnectivity profilesCreative performanceCreative behaviorCortexPrimary visual cortexMagnetic resonance imagingNetwork organizationNegative association
2019
Dissociable neural substrates of opioid and cocaine use identified via connectome-based modelling
Lichenstein SD, Scheinost D, Potenza MN, Carroll KM, Yip SW. Dissociable neural substrates of opioid and cocaine use identified via connectome-based modelling. Molecular Psychiatry 2019, 26: 4383-4393. PMID: 31719641, PMCID: PMC7214212, DOI: 10.1038/s41380-019-0586-y.Peer-Reviewed Original ResearchConceptsBrain statesDissociable neural substratesMultiple brain statesSubstance use outcomesHealthy comparison subjectsWhole-brain approachFMRI scanningFrontoparietal networkNeural substratesSubstance use treatmentNeural mechanismsDifferent brain statesFurther clinical relevanceDefault modeFMRI dataSubject replicationTreatment approachesReduced connectivityUse outcomesComparison subjectsNetwork strengthUse disordersSensory networksTreatment respondersSensory connectivityStructural brain network fingerprints of focal dystonia
Chirumamilla V, Dresel C, Koirala N, Gonzalez-Escamilla G, Deuschl G, Zeuner K, Muthuraman M, Groppa S. Structural brain network fingerprints of focal dystonia. Therapeutic Advances In Neurological Disorders 2019, 12: 1756286419880664. PMID: 31798688, PMCID: PMC6859688, DOI: 10.1177/1756286419880664.Peer-Reviewed Original ResearchBSP patientsHFS patientsBoNT treatmentHealthy controlsFocal dystoniaHemifacial spasmSensorimotor cortexFrontal cortexTemporal cortexStructural magnetic resonance imagingReduced connectivityGray matter volumeDifferent brain regionsSymptomatic reductionMovement disordersStructural brain networksGraph-based network analysisPatientsMatter volumeBlepharospasmDystoniaParietal cortexResonance imagingBrain regionsDecreased connectivity
2016
Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism
Gordon I, Jack A, Pretzsch CM, Vander Wyk B, Leckman JF, Feldman R, Pelphrey KA. Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism. Scientific Reports 2016, 6: 35054. PMID: 27845765, PMCID: PMC5109935, DOI: 10.1038/srep35054.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderIntranasal oxytocinSocial motivationSocial perceptionSocial-emotional informationFunctional magnetic resonance imagingPlacebo-controlled crossover designBiological motionSocial stimuliAngry voicesSocial deficitsSpectrum disorderOT administrationMesolimbic reward pathwayBehavioral treatmentBrain rewardReduced connectivityBrain regionsReward pathwayCortical sitesRewardPerceptionMotivationOxytocinBrain sites
2014
Default mode network subsystem alterations in obsessive–compulsive disorder
Beucke J, Sepulcre J, Eldaief M, Sebold M, Kathmann N, Kaufmann C. Default mode network subsystem alterations in obsessive–compulsive disorder. The British Journal Of Psychiatry 2014, 205: 376-382. PMID: 25257066, DOI: 10.1192/bjp.bp.113.137380.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderNeurobiological models of obsessive-compulsive disorderAssociated with self-referential processingModels of obsessive-compulsive disorderSeed-based resting-state functional connectivityObsessive-compulsive disorder groupHistory of affective disorderResting-state functional connectivityFunctional magnetic resonance imagingSelf-referential processingCorticostriatal brain regionsLife-time historyMode network componentsNeurobiological modelsAffective disordersBrain regionsFunctional connectivityReduced connectivityNeural systemsMedical statusAttention networkDisordered backgroundMagnetic resonance imagingDisordersNetwork integration
2011
Modelling schizophrenia using human induced pluripotent stem cells
Brennand K, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage F. Modelling schizophrenia using human induced pluripotent stem cells. Nature 2011, 473: 221-225. PMID: 21490598, PMCID: PMC3392969, DOI: 10.1038/nature09915.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntipsychotic AgentsCell DifferentiationCells, CulturedCellular ReprogrammingChildDisks Large Homolog 4 ProteinFemaleFibroblastsGene Expression ProfilingGene Expression RegulationHumansIntracellular Signaling Peptides and ProteinsLoxapineMaleMembrane ProteinsModels, BiologicalNeuritesNeuronsPhenotypePluripotent Stem CellsReceptors, GlutamateSchizophreniaYoung Adult
2006
Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability
Hampson M, Tokoglu F, Sun Z, Schafer RJ, Skudlarski P, Gore JC, Constable RT. Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability. NeuroImage 2006, 31: 513-519. PMID: 16497520, DOI: 10.1016/j.neuroimage.2005.12.040.Peer-Reviewed Original Research
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