2024
Effects of prazosin treatment on liver enzymes are moderated by alcohol withdrawal symptoms in individuals with alcohol use disorder
Martins B, Fogelman N, Tate M, Hermes G, Sinha R. Effects of prazosin treatment on liver enzymes are moderated by alcohol withdrawal symptoms in individuals with alcohol use disorder. Alcohol Clinical And Experimental Research 2024, 48: 507-515. PMID: 38258493, PMCID: PMC10939766, DOI: 10.1111/acer.15263.Peer-Reviewed Original ResearchAlcohol withdrawal symptomsAlcohol use disorderEffect of prazosin treatmentWithdrawal symptomsPrazosin treatmentLiver enzyme levelsLiver enzymesAlanine transaminasePrazosin groupAlcohol drinking outcomesAspartate transaminaseGamma-glutamyltransferaseSeverity of AWSLiver enzymes alanine transaminaseWithdrawal severityDrinking outcomesElevated liver enzymesAUD treatmentTreatment effectsAmount of alcoholSignificant liver pathologyGamma-glutamyltransferase levelsEnzyme levelsRandomized Controlled TrialsDisordered backgroundImaging a putative marker of brain cortisol regulation in alcohol use disorder
Verplaetse T, Hillmer A, Bhatt S, Rusowicz A, Li S, Nabulsi N, Matuskey D, Huang Y, McKee S, Cosgrove K. Imaging a putative marker of brain cortisol regulation in alcohol use disorder. Neurobiology Of Stress 2024, 29: 100609. PMID: 38304303, PMCID: PMC10832501, DOI: 10.1016/j.ynstr.2024.100609.Peer-Reviewed Original ResearchAlcohol use disorderAnterior cingulate cortexDrinking days/weekModerate to severe alcohol use disorderHealthy controlsHypothalamic-pituitary-adrenal (HPA) axisSevere alcohol use disorderPositron emission tomographyHPA axis dysfunctionHPA axis functionRelease of glucocorticoid hormonesAlcohol consumptionAssociated with drinkingVentromedial PFCCingulate cortexHigh-resolution research tomographHPA activityUse disorderDrinking episodesCortisol regulationAxis functionVmPFCPeripheral cortisolBrain availabilityDisordered background
2015
Positive Drinking Consequences Are Associated With Alcohol Use and Alcohol-Related Problems Among Veterans Seeking Treatment for Alcohol Use Disorder
Morean M, Cooney J. Positive Drinking Consequences Are Associated With Alcohol Use and Alcohol-Related Problems Among Veterans Seeking Treatment for Alcohol Use Disorder. Substance Use & Misuse 2015, 50: 1383-1389. PMID: 26452402, DOI: 10.3109/10826084.2015.1013133.Peer-Reviewed Original ResearchConceptsPositive Drinking Consequences QuestionnairePositive drinking consequencesAlcohol-related problemsDrinking consequencesAlcohol usePre-treatment alcohol useTreatment-seeking veteransAssociated with alcohol useVeterans seeking treatmentBehavior of veteransRates of heavy drinkingPretreatment drinkingAlcohol expectanciesIncremental validityUndergraduate sampleConsequences QuestionnaireAlcohol problemsDrinking behaviorAlcohol treatmentClinical populationsHeavy drinkingProgram intakeInternal consistencyAssociated with increased ratesDisordered background
2014
Default mode network subsystem alterations in obsessive–compulsive disorder
Beucke J, Sepulcre J, Eldaief M, Sebold M, Kathmann N, Kaufmann C. Default mode network subsystem alterations in obsessive–compulsive disorder. The British Journal Of Psychiatry 2014, 205: 376-382. PMID: 25257066, DOI: 10.1192/bjp.bp.113.137380.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderNeurobiological models of obsessive-compulsive disorderAssociated with self-referential processingModels of obsessive-compulsive disorderSeed-based resting-state functional connectivityObsessive-compulsive disorder groupHistory of affective disorderResting-state functional connectivityFunctional magnetic resonance imagingSelf-referential processingCorticostriatal brain regionsLife-time historyMode network componentsNeurobiological modelsAffective disordersBrain regionsFunctional connectivityReduced connectivityNeural systemsMedical statusAttention networkDisordered backgroundMagnetic resonance imagingDisordersNetwork integration
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply