2024
Total shoulder arthroplasty in patients with factor V Leiden
Zehner K, Sanchez J, Dhodapkar M, Modrak M, Luo X, Grauer J. Total shoulder arthroplasty in patients with factor V Leiden. Journal Of Shoulder And Elbow Surgery 2024, 34: 18-25. PMID: 38479723, DOI: 10.1016/j.jse.2024.01.041.Peer-Reviewed Original ResearchFactor V LeidenVenous thromboembolismAdverse eventsV LeidenTSA patientsRevision rateProphylactic agentFactor V Leiden patientsVTE prophylactic agentOdds ratioRisk of venous thromboembolismEffective treatment optionOdds of bleeding complicationsDeep vein thrombosisMultivariate logistic regressionEnd-stage glenohumeral osteoarthritisTotal shoulder arthroplastyInherited ThrombophiliaBleeding complicationsElixhauser Comorbidity IndexLonger-term outcomesPulmonary embolismProthrombotic stateVein thrombosisAdult patientsTrends in cerebral venous thrombosis before and during the COVID-19 pandemic: Analysis of the National Inpatient Sample
Klein P, Shu L, Qureshi M, Abdalkader M, Field T, Siegler J, Zhou L, Patel K, Al Kasab S, de Havenon A, Yaghi S, Qureshi A, Nguyen T. Trends in cerebral venous thrombosis before and during the COVID-19 pandemic: Analysis of the National Inpatient Sample. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107651. PMID: 38408574, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107651.Peer-Reviewed Original ResearchCerebral venous thrombosisIn-Hospital MortalityAssociated with in-hospital mortalityCVT incidenceNational Inpatient SampleIntracranial hemorrhageVenous thrombosisAtrial fibrillationMale sexPredictors of in-hospital mortalityAll-cause in-hospital mortalityIncidence of cerebral venous thrombosisInpatient SampleIncreasing ageStroke diagnosisCOVID-19 pandemicNationally representative estimatesICD-10 codesQuartile of incomeCensus dataMedian NIHSSProthrombotic stateHematological conditionsJoinpoint regressionMultivariate analysis
2023
Neuroimaging findings and neurological manifestations in hospitalized COVID-19 patients: Impact of cancer and ventilatory support status
McCarthy L, Khegai O, Goldstein J, Belani P, Pawha P, Kihira S, Mathew B, Gururangan K, Hao Q, Singh A, Navis A, Delman B, Jette N, Balchandani P. Neuroimaging findings and neurological manifestations in hospitalized COVID-19 patients: Impact of cancer and ventilatory support status. PLOS ONE 2023, 18: e0283614. PMID: 36961861, PMCID: PMC10038284, DOI: 10.1371/journal.pone.0283614.Peer-Reviewed Original ResearchConceptsHospitalized COVID-19 patientsMagnetic resonance imagingVentilatory supportNeurological manifestationsCOVID-19 patientsNeuroimaging findingsSupport statusImpact of cancerPolymerase chain reaction-confirmed COVID-19Mount Sinai Health SystemNon-cancer patientsAssociated with neurological manifestationsRetrospective observational studySinai Health SystemClinical neurological manifestationsHealth systemCentral nervous systemCOVID-19 cohortMorbidity associated with COVID-19Cancer statusAcute/subacute infarctionProthrombotic stateCOVID-19Systemic illnessFocal weakness
2020
Budd-Chiari Syndrome An Uncommon Cause of Chronic Liver Disease that Cannot Be Missed
Haque LYK, Lim JK. Budd-Chiari Syndrome An Uncommon Cause of Chronic Liver Disease that Cannot Be Missed. Clinics In Liver Disease 2020, 24: 453-481. PMID: 32620283, DOI: 10.1016/j.cld.2020.04.012.BooksConceptsBudd-Chiari syndromeLiver diseaseHepatic venous outflow obstructionPrimary Budd-Chiari syndromeDevelopment of cirrhosisVenous outflow obstructionChronic liver diseaseLife-threatening diagnosisVariable clinical presentationPortal hypertensionProthrombotic stateVenous obstructionLifelong anticoagulationMost patientsOutflow obstructionUncommon causeClinical presentationRare causeRisk factorsHepatocellular carcinomaHigh indexPatientsDiseaseSyndromeObstruction
2017
Risk Factors for Pregnancy-Associated Stroke in Women With Preeclampsia
Miller EC, Gatollari HJ, Too G, Boehme AK, Leffert L, Marshall RS, Elkind MSV, Willey JZ. Risk Factors for Pregnancy-Associated Stroke in Women With Preeclampsia. Stroke 2017, 48: 1752-1759. PMID: 28546324, PMCID: PMC5539968, DOI: 10.1161/strokeaha.117.017374.Peer-Reviewed Original ResearchConceptsPregnancy-associated strokeRisk factorsChronic hypertensionProthrombotic stateOdds ratioMultivariable conditional logistic regression modelsConditional logistic regression modelsNew York State hospitalsIndependent risk factorVascular risk factorsSeverity of preeclampsiaLogistic regression modelsRace/ethnicityPregnancy complicationsSevere preeclampsiaMultivariable analysisInpatient DatabaseProthrombotic conditionsPreeclampsiaHigh riskClose monitoringNew York State DepartmentState HospitalCoagulopathyBilling data
2013
Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome
Lemaire M, Frémeaux-Bacchi V, Schaefer F, Choi M, Tang WH, Le Quintrec M, Fakhouri F, Taque S, Nobili F, Martinez F, Ji W, Overton JD, Mane SM, Nürnberg G, Altmüller J, Thiele H, Morin D, Deschenes G, Baudouin V, Llanas B, Collard L, Majid MA, Simkova E, Nürnberg P, Rioux-Leclerc N, Moeckel GW, Gubler MC, Hwa J, Loirat C, Lifton RP. Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome. Nature Genetics 2013, 45: 531-536. PMID: 23542698, PMCID: PMC3719402, DOI: 10.1038/ng.2590.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAtypical Hemolytic Uremic SyndromeChildChild, PreschoolDiacylglycerol KinaseExomeFemaleGenes, RecessiveHemolytic-Uremic SyndromeHumansImmunoenzyme TechniquesInfantMaleMolecular Sequence DataMutationRenal Insufficiency, ChronicThrombocytopeniaThrombotic Microangiopathies
2008
Acute Onset Human Atrial Fibrillation Is Associated With Local Cardiac Platelet Activation and Endothelial Dysfunction
Akar JG, Jeske W, Wilber DJ. Acute Onset Human Atrial Fibrillation Is Associated With Local Cardiac Platelet Activation and Endothelial Dysfunction. Journal Of The American College Of Cardiology 2008, 51: 1790-1793. PMID: 18452786, DOI: 10.1016/j.jacc.2007.11.083.Peer-Reviewed Original ResearchConceptsAcute onset atrial fibrillationSystemic platelet activationRisk factorsPlatelet activationHypercoagulable stateAtrial fibrillationAF groupThrombin generationBlood samplesControl groupUnderwent radiofrequency catheter ablationPlatelet P-selectin expressionOnset atrial fibrillationBaseline blood samplesRadiofrequency catheter ablationMinutes of onsetBeats/minP-selectin expressionBurst atrial pacingHuman atrial fibrillationNitric oxide productionEnzyme-linked immunosorbentLocal thrombin generationInflammatory markersProthrombotic stateWarm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition
Kon Z, Brown E, Grant M, Ozeki T, Burris N, Collins M, Kwon M, Poston R. Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition. European Journal Of Cardio-Thoracic Surgery 2008, 33: 215-221. PMID: 18068996, PMCID: PMC2605708, DOI: 10.1016/j.ejcts.2007.11.008.Peer-Reviewed Original ResearchConceptsPump coronary artery bypassCoronary artery bypassTranscardiac gradientCoronary occlusionArtery bypassMyocardial ischemiaTNF-alphaCoronary sinus bloodEarly graft failureRegional myocardial ischemiaProthrombotic stateGraft failureProtamine administrationSinus bloodConsecutive patientsIschemic injuryMyocardial injuryIL-8Warm ischemiaPathophysiologic consequencesSeries of biomarkersCoagulation systemOPCABIschemiaInflammation
2004
Elevated sEPCR and PAI-1 Levels, but Not sThrombomodulin Levels in Normal Pregnancy.
Arkel Y, Paidas M, Ku D, Triche E, Lam X, Ku E, Lockwood C. Elevated sEPCR and PAI-1 Levels, but Not sThrombomodulin Levels in Normal Pregnancy. Blood 2004, 104: 3996. DOI: 10.1182/blood.v104.11.3996.3996.Peer-Reviewed Original ResearchEndothelial protein C receptorAdverse pregnancy outcomesPro-inflammatory cytokinesNormal pregnancyProtein C systemDecidual cellsEndothelial cellsProtein SEndometrial decidual cellsNon-pregnant controlsProtein C receptorCell surface proteinsPlasminogen activator inhibitorCell-surface thrombomodulinPregnancy outcomesProthrombotic statePlasma thrombomodulinNP patientsEC damageSurface proteinsControl of thrombosisSTM levelsTrimester samplesPregnancyFibrinolytic system
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply