2021
A graph theory‐based whole brain approach to assess mood state differences in adolescents and young adults with bipolar disorder
Goldman DA, Sankar A, Colic L, Villa L, Kim JA, Pittman B, Constable RT, Scheinost D, Blumberg HP. A graph theory‐based whole brain approach to assess mood state differences in adolescents and young adults with bipolar disorder. Bipolar Disorders 2021, 24: 412-423. PMID: 34665907, PMCID: PMC9016085, DOI: 10.1111/bdi.13144.Peer-Reviewed Original ResearchConceptsLenticular nucleusFunctional connectivityPrefrontal cortexMood statesYoung adultsLimited brain regionsAcute mood statesRight lenticular nucleusBipolar I disorderDorsal prefrontal cortexPrevious neuroimaging studiesWhole-brain approachTemporal functional connectivityFunctional magnetic resonanceLeft prefrontal cortexBrain dysfunctionContralateral homologuesHealthy controlsI disordersDepression scoresICD increasesRight cerebellumBipolar disorderEarly interventionBrain regions
2020
Neural responsivity to social rewards in autistic female youth
Lawrence KE, Hernandez LM, Eilbott J, Jack A, Aylward E, Gaab N, Van Horn JD, Bernier RA, Geschwind DH, McPartland JC, Nelson CA, Webb SJ, Pelphrey KA, Bookheimer SY, Dapretto M. Neural responsivity to social rewards in autistic female youth. Translational Psychiatry 2020, 10: 178. PMID: 32488083, PMCID: PMC7266816, DOI: 10.1038/s41398-020-0824-8.Peer-Reviewed Original ResearchConceptsImplicit learning taskSocial rewardsAutistic girlsAutistic boysLearning taskSocial reward processingSocial reward systemFemale youthPrevious neuroimaging studiesFunctional magnetic resonanceLateral frontal cortexSocial stimuliNeural responsivityReward processingSocial motivationRewarding stimuliAnterior insulaGreater activityNeural activationNeuroimaging studiesPotential sex differencesRewarding natureSalience detectionAutistic femalesBehavioral evidence
2013
Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability?
Kelly P, Viding E, Wallace G, Schaer M, De Brito S, Robustelli B, McCrory E. Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability? Biological Psychiatry 2013, 74: 845-852. PMID: 23954109, DOI: 10.1016/j.biopsych.2013.06.020.Peer-Reviewed Original ResearchConceptsCortical thicknessLingual gyrusAnterior cingulateLeft middle temporal areaSuperior frontal gyrusBrain volume differencesAtypical neural structureCortical surface areaMiddle temporal areaPrevious neuroimaging studiesGyrification abnormalitiesTemporal lobePsychiatric disordersLocal gyrificationPsychiatric riskHistory of abuseStructural abnormalitiesTemporal areaClinical disordersBiological markersOrbitofrontal cortexPrefrontal cortexBrain structuresGyrusNeuroimaging studies
2012
Reduced orbitofrontal and temporal grey matter in a community sample of maltreated children
De Brito S, Viding E, Sebastian C, Kelly P, Mechelli A, Maris H, McCrory E. Reduced orbitofrontal and temporal grey matter in a community sample of maltreated children. Journal Of Child Psychology And Psychiatry 2012, 54: 105-112. PMID: 22880630, DOI: 10.1111/j.1469-7610.2012.02597.x.Peer-Reviewed Original ResearchConceptsMedial orbitofrontal cortexPsychiatric disordersMiddle temporal gyrusOrbitofrontal cortexTemporal lobeGray matterTemporal gyrusConcurrent psychiatric disordersTemporal gray matterGray matter volumeVoxel-based morphometryCommunity sampleLeft middle temporal gyrusAtypical neural structurePrevious neuroimaging studiesNeurobiological risk factorsRisk factorsLevel of anxietyMatter volumePosttraumatic stress symptomsPsychiatric vulnerabilityConcurrent anxietyPrefrontal cortexCortexNeuroimaging studiesNeural Mechanisms of Decision Making in Hoarding Disorder
Tolin DF, Stevens MC, Villavicencio AL, Norberg MM, Calhoun VD, Frost RO, Steketee G, Rauch SL, Pearlson GD. Neural Mechanisms of Decision Making in Hoarding Disorder. JAMA Psychiatry 2012, 69: 832-841. PMID: 22868937, PMCID: PMC3506167, DOI: 10.1001/archgenpsychiatry.2011.1980.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingCerebral CortexDecision MakingDiagnostic and Statistical Manual of Mental DisordersEvoked PotentialsExpressed EmotionFemaleGyrus CinguliHoarding DisorderHospitals, VoluntaryHumansMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysObsessive BehaviorSickness Impact ProfileConceptsHealthy control subjectsObsessive-compulsive disorderAnterior cingulate cortexNeural mechanismsCingulate cortexBrain regionsNeural activityAppropriate emotional responsesFrontal brain regionsFunctional magnetic resonance imaging (fMRI) signalsPrevious neuroimaging studiesUnique diagnostic entityFunctional magnetic resonanceMagnetic resonance imaging signalsControl subjectsImpaired decisionInsula functionEmotional significanceAffective statesDepressive symptomsHoarding DisorderEmotional responsesNeuroimaging studiesPatientsPoor insight
2005
Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals
Li CS, Milivojevic V, Constable RT, Sinha R. Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Research 2005, 140: 271-280. PMID: 16290108, DOI: 10.1016/j.pscychresns.2005.09.002.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulateAbstinent cocaine-dependent subjectsCocaine-dependent subjectsCannabis abuseCannabis abusersCocaine-dependent individualsAnterior cingulateEmotional stressBOLD signalUrine drug screeningSame statistical thresholdDrug use historyFrontal cortical areasHeavy cannabis useLevel-dependent contrastPrevious neuroimaging studiesFunctional magnetic resonanceFrontal cortexCortical areasAlcohol consumptionCortical activationEmotional stress taskUse of marijuanaBrain regionsDecreased activationHemispheric differences in hemodynamics elicited by auditory oddball stimuli
Stevens MC, Calhoun VD, Kiehl KA. Hemispheric differences in hemodynamics elicited by auditory oddball stimuli. NeuroImage 2005, 26: 782-792. PMID: 15955488, PMCID: PMC2759643, DOI: 10.1016/j.neuroimage.2005.02.044.Peer-Reviewed Original ResearchConceptsNovel stimuliInfrequent targetsRight hemisphereHemispheric differencesGreater right hemisphere activationTask-relevant target stimuliAuditory oddball stimuliEvent-related fMRIParietal lobe activityRight hemisphere activationFrequent standard stimuliTask-irrelevant novel stimuliPrevious neuroimaging studiesHealthy adult participantsAttentional processesNovelty processingSalient stimuliTarget stimuliOddball stimuliOddball taskNeuroimaging studiesStandard stimuliInfrequent novelLeft hemisphereHemodynamic activity
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