2024
Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking
Johnson E, Austin-Zimmerman I, Thorpe H, Levey D, Baranger D, Colbert S, Demontis D, Khokhar J, Davis L, Edenberg H, Di Forti M, Sanchez-Roige S, Gelernter J, Agrawal A. Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking. Neuropsychopharmacology 2024, 49: 1655-1665. PMID: 38906991, PMCID: PMC11399264, DOI: 10.1038/s41386-024-01886-3.Peer-Reviewed Original ResearchCannabis use disorderUse disorderPleiotropic lociCo-occurring substance useHeavy cannabis useInvestigation of schizophreniaSubstance use disordersGenome-wide studiesGenetic factorsMental health conditionsExecutive functionCannabis useSubstance useLead variantsSchizophreniaGenetic variantsEuropean ancestryEuropean ancestry dataRisk-takingSCZHeritable factorsCannabisDisordersTobacco smokeGenetic correlations
2005
Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals
Li CS, Milivojevic V, Constable RT, Sinha R. Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Research 2005, 140: 271-280. PMID: 16290108, DOI: 10.1016/j.pscychresns.2005.09.002.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulateAbstinent cocaine-dependent subjectsCocaine-dependent subjectsCannabis abuseCannabis abusersCocaine-dependent individualsAnterior cingulateEmotional stressBOLD signalUrine drug screeningSame statistical thresholdDrug use historyFrontal cortical areasHeavy cannabis useLevel-dependent contrastPrevious neuroimaging studiesFunctional magnetic resonanceFrontal cortexCortical areasAlcohol consumptionCortical activationEmotional stress taskUse of marijuanaBrain regionsDecreased activation
2003
The Time Course and Significance of Cannabis Withdrawal
Budney AJ, Moore BA, Vandrey RG, Hughes JR. The Time Course and Significance of Cannabis Withdrawal. Journal Of Psychopathology And Clinical Science 2003, 112: 393-402. PMID: 12943018, DOI: 10.1037/0021-843x.112.3.393.Peer-Reviewed Original ResearchConceptsCannabis withdrawalTime courseDevelopment of dependenceHeavy cannabis useWithdrawal syndromeOutpatient studyWithdrawal symptomsAbstinence phaseSleep problemsStomach painBody weightDay 1Day 2Clinical importanceCannabis usePeak effectMarijuana usersWithdrawalParallel assessmentCoursePainSmokingSyndromeSymptomsWithdrawal patterns
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