2018
Symptom Insight in Pediatric Obsessive-Compulsive Disorder: Outcomes of an International Aggregated Cross-Sectional Sample
Selles RR, Højgaard DRMA, Ivarsson T, Thomsen PH, McBride N, Storch EA, Geller D, Wilhelm S, Farrell LJ, Waters AM, Mathieu S, Lebowitz E, Elgie M, Soreni N, Stewart SE. Symptom Insight in Pediatric Obsessive-Compulsive Disorder: Outcomes of an International Aggregated Cross-Sectional Sample. Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 57: 615-619.e5. PMID: 30071984, PMCID: PMC7176075, DOI: 10.1016/j.jaac.2018.04.012.Peer-Reviewed Original Research
2012
Neural Mechanisms of Decision Making in Hoarding Disorder
Tolin DF, Stevens MC, Villavicencio AL, Norberg MM, Calhoun VD, Frost RO, Steketee G, Rauch SL, Pearlson GD. Neural Mechanisms of Decision Making in Hoarding Disorder. JAMA Psychiatry 2012, 69: 832-841. PMID: 22868937, PMCID: PMC3506167, DOI: 10.1001/archgenpsychiatry.2011.1980.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingCerebral CortexDecision MakingDiagnostic and Statistical Manual of Mental DisordersEvoked PotentialsExpressed EmotionFemaleGyrus CinguliHoarding DisorderHospitals, VoluntaryHumansMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysObsessive BehaviorSickness Impact ProfileConceptsHealthy control subjectsObsessive-compulsive disorderAnterior cingulate cortexNeural mechanismsCingulate cortexBrain regionsNeural activityAppropriate emotional responsesFrontal brain regionsFunctional magnetic resonance imaging (fMRI) signalsPrevious neuroimaging studiesUnique diagnostic entityFunctional magnetic resonanceMagnetic resonance imaging signalsControl subjectsImpaired decisionInsula functionEmotional significanceAffective statesDepressive symptomsHoarding DisorderEmotional responsesNeuroimaging studiesPatientsPoor insightPoor insight in pediatric obsessive compulsive disorder: Developmental considerations, treatment implications, and potential strategies for improving insight
Adelman C, Lebowitz E. Poor insight in pediatric obsessive compulsive disorder: Developmental considerations, treatment implications, and potential strategies for improving insight. Journal Of Obsessive-Compulsive And Related Disorders 2012, 1: 119-124. DOI: 10.1016/j.jocrd.2012.02.003.Peer-Reviewed Original ResearchPediatric obsessive-compulsive disorderObsessive-compulsive disorderPoor insightCompulsive disorderTreatment implicationsCognitive behavioral therapyBehavioral therapyGreater symptom severityObsessive thoughtsOCD symptomsDevelopmental considerationsChildren's insightGreater functional impairmentDevelopmental contextPoor treatment responseSymptom severityDegree of insightEmpirical researchFunctional impairmentDisordersImplicationsTreatment responseImpairmentThoughtChildrenClinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study
Torres A, Fontenelle L, Ferrão Y, do Rosário M, Torresan R, Miguel E, Shavitt R. Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study. Journal Of Psychiatric Research 2012, 46: 724-732. PMID: 22464941, DOI: 10.1016/j.jpsychires.2012.03.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresOCD patientsLogistic regressionDSM-IV OCD patientsCertain clinical featuresCross-sectional studyAttention-deficit/hyperactivity disorderStatistical univariate analysisBrazilian Research ConsortiumDeficit/hyperactivity disorderHigher anxiety scoresYale-Brown ObsessiveSymptom onsetInsidious onsetMulticenter studyObsessive-compulsive spectrum disordersSectional studyPossible confoundersUnivariate analysisTic disordersHoarding dimensionPatientsSymptomsPoor insightWorking with hoarding vs. non-hoarding clients: A survey of professionals' attitudes and experiences
Tolin D, Frost R, Steketee G. Working with hoarding vs. non-hoarding clients: A survey of professionals' attitudes and experiences. Journal Of Obsessive-Compulsive And Related Disorders 2012, 1: 48-53. DOI: 10.1016/j.jocrd.2011.11.004.Peer-Reviewed Original Research
2011
Dimensional correlates of poor insight in obsessive–compulsive disorder
Jakubovski E, Pittenger C, Torres AR, Fontenelle LF, do Rosario MC, Ferrão YA, de Mathis MA, Miguel EC, Bloch MH. Dimensional correlates of poor insight in obsessive–compulsive disorder. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2011, 35: 1677-1681. PMID: 21640153, PMCID: PMC4048951, DOI: 10.1016/j.pnpbp.2011.05.012.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderPoor insightYale-Brown ObsessiveSymptom severityTreatment responseCompulsive ScaleAxis I DSMLevel of insightDetailed clinical assessmentCross-sectional studyTotal symptom severityStructured Clinical InterviewLarge clinical cohortOCD severityDimensional correlatesSocio-demographic questionnaireClinical variablesPharmacological trialsComorbid depressionBrazilian patientsClinical assessmentClinical cohortBrown AssessmentClinical InterviewPatients
2001
Fixity of belief, perceptual aberration, and magical ideation in obsessive–compulsive disorder
Tolin D, Abramowitz J, Kozak M, Foa E. Fixity of belief, perceptual aberration, and magical ideation in obsessive–compulsive disorder. Journal Of Anxiety Disorders 2001, 15: 501-510. PMID: 11764309, DOI: 10.1016/s0887-6185(01)00078-0.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMagical ideationPerceptual distortionStandard cognitive behavioral therapyReligious obsessionsPsychotic-like featuresCognitive behavioral therapyTypes of obsessionsPsychotic-like symptomsPerceptual AberrationDistressing obsessionsOCD severityOCD patientsPoor insightMere differencePrevious findingsObsessionPsychotic symptomsIdeationBeliefsParticipantsIndividualsMore researchTreatment outcomesDisordersTranstorno obsessivo-compulsivo: possíveis subtipos
Hounie A, de A Brotto S, Diniz J, Chacon P, Miguel E. Transtorno obsessivo-compulsivo: possíveis subtipos. Brazilian Journal Of Psychiatry 2001, 23: 13-16. DOI: 10.1590/s1516-44462001000600005.Peer-Reviewed Original ResearchPutative subtypesUnderlying pathophysiological substrateEarly age onsetMore specific treatmentsGenetic family studiesExistence of subtypesRheumatic feverDisease coursePathophysiological substrateClinical featuresTreatment responseSpecific treatmentAge onsetPoor insightHeterogeneous disorderSubtypesPossible subgroupsFamily studiesSubgroupsOCDPhenotypic characterizationFeverGroup
1999
Insight in Schizophrenia: Its Relationship to Measures of Executive Functions
MOHAMED S, FLEMING S, PENN D, SPAULDING W. Insight in Schizophrenia: Its Relationship to Measures of Executive Functions. The Journal Of Nervous And Mental Disease 1999, 187: 525-531. PMID: 10496507, DOI: 10.1097/00005053-199909000-00001.Peer-Reviewed Original ResearchConceptsExecutive functionAspects of executiveNegative symptomsChronic schizophreniaExecutive functioningNeuropsychological processesGeneral intelligenceNeuropsychological functionAssess UnawarenessGroup of individualsPoor insightMental disordersSchizophreniaUnawarenessSpecific symptomsMisattributionIndividualsPerformance measuresSymptomsMeasuresFunctioningLack of awarenessMotivationDeficitsIntelligence
1994
Insight and Psychosocial Treatment Compliance in Schizophrenia
Lysaker P, Bell M, Milstein R, Bryson G, Beam-Goulet J. Insight and Psychosocial Treatment Compliance in Schizophrenia. Psychiatry 1994, 57: 307-315. PMID: 7899525, DOI: 10.1080/00332747.1994.11024695.Peer-Reviewed Original ResearchConceptsPoor insightLevels of psychopathologyPsychosocial treatment compliancePoor medication complianceRelationship of insightWork rehabilitation programWeeks of participationLower intelligence quotientMedication complianceTreatment compliancePsychosocial treatmentsRehabilitation programCognitive deficitsPsychosocial functioningFifth weekIntelligence quotientSchizophreniaWeeksPsychopathologyPoor social skillsCognitive disorganizationComplianceHeightened levelsPatientsLevelsInsight and Cognitive Impairment in Schizophrenia Performance on Repeated Administrations of the Wisconsin Card Sorting Test
LYSAKER P, BELL M. Insight and Cognitive Impairment in Schizophrenia Performance on Repeated Administrations of the Wisconsin Card Sorting Test. The Journal Of Nervous And Mental Disease 1994, 182: 656-660. PMID: 7964675, DOI: 10.1097/00005053-199411000-00010.Peer-Reviewed Original ResearchConceptsPoor insightCognitive impairmentImpaired insightWisconsin Card Sorting TestCard Sorting TestPoor treatment complianceSorting TestTreatment complianceRepeated administrationNeuropsychological dysfunctionCognitive deficitsPatientsSchizophreniaImpairmentPerformance deficitsAdministrationSchizophrenia performanceSubjectsDeficitsPerseverative errorsDysfunctionEtiologyIllnessEffects of IQ
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