2025
Interventions to Mitigate EHR and Documentation Burden in Health Professions Trainees: A Scoping Review
Levy D, Rossetti S, Brandt C, Melnick E, Hamilton A, Rinne S, Womack D, Mohan V. Interventions to Mitigate EHR and Documentation Burden in Health Professions Trainees: A Scoping Review. Applied Clinical Informatics 2025, 16: 111-127. PMID: 39366661, PMCID: PMC11798655, DOI: 10.1055/a-2434-5177.Peer-Reviewed Original ResearchEHR burdenElectronic health recordsHealth professions traineesExperiences of interventionsHealth professionalsDocumentation burdenInpatient settingExperienced health professionalsBurden modelPeer-reviewed studiesQuasi-experimental designDesigning new interventionsShift handoffsEHR workflowPhysician traineesPerspective of interventionHealth recordsPRISMA-ScRScoping ReviewLiving tasksConcept clarificationTeam communicationTrainee experienceWorkflow modelNew interventions
2023
Integrating stakeholder feedback into the design of a peer-delivered primary care wellness program: A rapid qualitative study
Johnson E, Possemato K, Chinman M, True G, Hedges J, Hampton B, Edelman E, Maisto S. Integrating stakeholder feedback into the design of a peer-delivered primary care wellness program: A rapid qualitative study. BMC Health Services Research 2023, 23: 1370. PMID: 38062433, PMCID: PMC10701982, DOI: 10.1186/s12913-023-10324-x.Peer-Reviewed Original ResearchConceptsBehavioral health concernsPrimary careHealth concernWhole Health modelPrimary care settingBehavioral health treatmentCare settingsSemi-structured qualitative interviewsHealth treatmentMaximum variation strategyRapid qualitative studyConsolidated FrameworkNew interventionsStakeholder feedbackVA staffWellness programsHealth modelImplementation researchInitial trialCareNational sampleFrontline staffInterventionVeteransStaff members
2022
A modified video-feedback intervention for carers of foster children aged 6 years and under with reactive attachment disorder: a feasibility study and pilot RCT
Oliveira P, Stevens E, Barge L, Comyn J, Langley K, Ramchandani P, Wright B, Woolgar M, Kennedy E, Byford S, Shearer J, Scott S, Barlow J, Glaser D, Senior R, Fonagy P, Fearon P. A modified video-feedback intervention for carers of foster children aged 6 years and under with reactive attachment disorder: a feasibility study and pilot RCT. Health Technology Assessment 2022, 26: 1-106. PMID: 35959710, PMCID: PMC9421559, DOI: 10.3310/sliz1119.Peer-Reviewed Original ResearchConceptsVideo-feedback InterventionCase seriesMAIN OUTCOMEReactive attachment disorderNIHR Journals Library websiteHealth Technology Assessment programmeNew interventionsAdolescent mental health servicesFuture full-scale trialFurther project informationSmall case seriesTreatment manualWide inclusion criteriaTechnology Assessment programmeMental health servicesTarget sample sizeEffective treatment approachEvidence-based interventionsAttachment disorderLarge-scale trialsHealth service practitionersMental health professionalsTreatment completenessUsual carePilot RCTChildren in foster care with symptoms of reactive attachment disorder: feasibility randomised controlled trial of a modified video-feedback parenting intervention
Oliveira P, Barge L, Stevens E, Byford S, Shearer J, Spies R, Comyn J, Langley K, Ramchandani P, Wright B, Woolgar M, Kennedy E, Scott S, Barlow J, Glaser D, Senior R, Fonagy P, Fearon P. Children in foster care with symptoms of reactive attachment disorder: feasibility randomised controlled trial of a modified video-feedback parenting intervention. BJPsych Open 2022, 8: e134. PMID: 35848060, PMCID: PMC9347233, DOI: 10.1192/bjo.2022.538.Peer-Reviewed Original ResearchReactive attachment disorderWide inclusion criteriaParenting interventionsPost-treatment assessmentEvidence-based interventionsLarge-scale trialsMental health professionalsTreatment completenessUsual careCase seriesFeasibility outcomesPilot RCTAttachment disorderCare settingsInclusion criteriaHealth professionalsNew interventionsRecruitment barriersCare contextInterventionIntervention programsTrialsCareCarersRAD symptoms
2019
Noninferiority Designed Cardiovascular Trials in Highest-Impact Journals
Bikdeli B, Welsh JW, Akram Y, Punnanithinont N, Lee I, Desai NR, Kaul S, Stone G, Ross JS, Krumholz HM. Noninferiority Designed Cardiovascular Trials in Highest-Impact Journals. Circulation 2019, 140: 379-389. PMID: 31177811, PMCID: PMC8416048, DOI: 10.1161/circulationaha.119.040214.Peer-Reviewed Original ResearchConceptsNoninferiority marginNoninferiority trialCardiovascular trialsAllocation concealmentLower riskOpen labelHazard ratioRelative riskMethodological qualityProportion of trialsIndependent reviewersRisk differenceNew England JournalNoninferiorityHigh-impact journalsNew interventionsTrialsCohortDiscrepant resultsProtocol analysisTime trendsRiskTreatInterventionFactors
2017
The Herts and minds study: evaluating the effectiveness of mentalization-based treatment (MBT) as an intervention for children in foster care with emotional and/or behavioural problems: a phase II, feasibility, randomised controlled trial
Midgley N, Besser S, Dye H, Fearon P, Gale T, Jefferies-Sewell K, Irvine K, Robinson J, Wyatt S, Wellsted D, Wood S. The Herts and minds study: evaluating the effectiveness of mentalization-based treatment (MBT) as an intervention for children in foster care with emotional and/or behavioural problems: a phase II, feasibility, randomised controlled trial. Pilot And Feasibility Studies 2017, 3: 12. PMID: 28250962, PMCID: PMC5320756, DOI: 10.1186/s40814-017-0127-x.Peer-Reviewed Original ResearchMentalization-based treatmentUsual clinical careHigh-quality researchControl feasibility trialFeatures of therapyBackgroundA significant proportionMental health problemsNHS Foundation TrustNICE guidelinesFeasibility trialBehavioral difficultiesTwo-armClinical careEffective treatmentSocial care systemsHealth problemsNew interventionsFoundation TrustCare systemTrialsVulnerable populationsDiscussionThis studyCarePhase IIChildrenTrauma resiliency and posttraumatic growth.
Tsai J, Harpaz-Rotem I, Pietrzak R, Southwick S. Trauma resiliency and posttraumatic growth. 2017, 89-113. DOI: 10.1037/0000020-005.Peer-Reviewed Original ResearchPosttraumatic growthPositive psychological changesTrauma-related psychopathologyFace of traumaPrevalence of resilienceMeasurement of resilienceBrief case examplesTraumatic eventsPsychological changesField of traumatologyNew interventionsResilienceSynonymous conceptsCase exampleFuture directionsInterventionMore researchResearchCursory reviewPsychopathologyTraumaAdditional readingReadingHuman lifeResiliency
2016
Relationship between Advanced Glycation End Products and Steroidogenesis in PCOS
Garg D, Merhi Z. Relationship between Advanced Glycation End Products and Steroidogenesis in PCOS. Reproductive Biology And Endocrinology 2016, 14: 71. PMID: 27769286, PMCID: PMC5073880, DOI: 10.1186/s12958-016-0205-6.Peer-Reviewed Original ResearchMeSH Keywords3-Hydroxysteroid DehydrogenasesAnimalsCholesterol Side-Chain Cleavage EnzymeFemaleGlycation End Products, AdvancedGonadal Steroid HormonesGranulosa CellsHumansOvaryPhosphoproteinsPolycystic Ovary SyndromeReceptors, LHReceptors, PeptideReceptors, Transforming Growth Factor betaSteroid 17-alpha-HydroxylaseTheca CellsConceptsAdvanced glycation end productsOvaries of womenTheca cell functionGlycation end productsCell functionHormone receptor expressionSteroidogenic enzyme activitiesSteroidogenic acute regulatory proteinAbnormal steroidogenesisPCOS modelOvarian dysfunctionAcute regulatory proteinReceptor expressionPCOSFollicular developmentTheca cellsGranulosa cellsSystematic reviewNew interventionsHormone receptorsEnzyme cytochrome P450SteroidogenesisEnd productsGranulosaCytochrome P450Intrinsic and Extrinsic Motivation and Learning in Schizophrenia
Kremen L, Fiszdon J, Kurtz M, Silverstein S, Choi J. Intrinsic and Extrinsic Motivation and Learning in Schizophrenia. Current Behavioral Neuroscience Reports 2016, 3: 144-153. DOI: 10.1007/s40473-016-0078-1.Peer-Reviewed Original ResearchIntrinsic motivationExtrinsic motivationGoal-directed behaviorTypes of motivationRole of effortImportance of rewardMotivation impairmentsPsychological needsExternal rewardsMotivation researchBehavioral correlatesBehavioral interventionsNegative symptomsMotivationPsychiatric recoveryRewardNew interventionsSchizophreniaAmotivationInterventionAnhedoniaDeficitsCorrelatesImpairmentBehavior
2015
Fathers for Change for Substance Use and Intimate Partner Violence: Initial Community Pilot
Stover CS. Fathers for Change for Substance Use and Intimate Partner Violence: Initial Community Pilot. Family Process 2015, 54: 600-609. PMID: 25683252, PMCID: PMC4534360, DOI: 10.1111/famp.12136.Peer-Reviewed Original ResearchConceptsIndividual drug counselingIntimate partner violenceSubstance abuseCo-occurring intimate partner violenceIDC groupIntervention periodPartner violenceDrug counselingLess IPVChange groupFurther evaluationNew interventionsSubstance useIntervention programsMenGreater satisfactionInterventionTreatmentChildrenAbuseGroupLarge sample
2014
Board #133 - Research Abstract Implementation and Impact of a Just-in-Time Assessment to Determine Intern Readiness to Perform Their First Infant Lumbar Puncture (Submission #8534)
Kessler D, Auerbach M, Chang T, Fein D, Gerard J, Lee M, Mehta R, Pusic M, Trainor J. Board #133 - Research Abstract Implementation and Impact of a Just-in-Time Assessment to Determine Intern Readiness to Perform Their First Infant Lumbar Puncture (Submission #8534). Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2014, 9: 416. DOI: 10.1097/01.sih.0000459303.20953.b5.Peer-Reviewed Original ResearchInfant lumbar punctureAssessment pathwayLumbar punctureSuccess rateClinical success rateLarge clinical effectAmerican Medical AssociationLP success rateClinical proceduresClinical effect sizeLumbar puncture procedureLP attemptsClinical effectsPathway adherenceProspective studyClinical successCohorts of internsLarger sample sizePuncture procedurePatient safetyNew interventionsRating ScaleEmergency medicineRoyal CollegeGlobal rating scale
2013
The National Institutes of Health Center for Human Immunology, Autoimmunity, and Inflammation: history and progress
Dickler H, McCoy J, Nussenblatt R, Perl S, Schwartzberg P, Tsang J, Wang E, Young N. The National Institutes of Health Center for Human Immunology, Autoimmunity, and Inflammation: history and progress. Annals Of The New York Academy Of Sciences 2013, 1285: 133-147. PMID: 23692568, DOI: 10.1111/nyas.12101.Peer-Reviewed Original ResearchConceptsHuman immunologyDepth clinical phenotypingCommon pathogenic pathwayNew therapeutic modalitiesHuman immune systemDisease progressionImmune cellsHealth centersClinical phenotypingTherapeutic modalitiesPathogenic pathwaysImmune systemNew interventionsMultiplex technologyPotential targetNational InstituteAutoimmunityInflammationEpigenetic modulationDiseaseImmunologyIntramural programsInterventionGene expressionDepth assessmentPhenomenological and Participatory Research on Schizophrenia: Recovering the Person in Theory and Practice
Davidson L, Stayner D, Lambert S, Smith P, Sledge W. Phenomenological and Participatory Research on Schizophrenia: Recovering the Person in Theory and Practice. Journal Of Social Issues 2013, 53: 767-784. DOI: 10.1111/0022-4537.00048.Peer-Reviewed Original ResearchSerious mental illnessClinical practiceMental illnessMental patientsExperience of hospitalizationInpatient admissionsRecidivist patientsPatientsReadmissionNew interventionsEarly detectionParticipatory research methodsDisordersIllnessProblem of recidivismInterventionCultural stigmaPersonsHospitalizationRelapseSatisfying lifeAdmissionFailureHospitalSymptoms
2012
Neuroplasticity‐based computerized cognitive remediation for geriatric depression
Morimoto SS, Wexler BE, Alexopoulos GS. Neuroplasticity‐based computerized cognitive remediation for geriatric depression. International Journal Of Geriatric Psychiatry 2012, 27: 1239-1247. PMID: 22451346, PMCID: PMC3387346, DOI: 10.1002/gps.3776.Peer-Reviewed Original ResearchConceptsComputerized cognitive remediationCognitive remediationExecutive dysfunctionGeriatric depressionSpecific executive deficitsSpecific neurocognitive deficitsSpecific cerebral networksNovel treatment interventionsAvailable treatment studiesNovel treatment modelExecutive deficitsEmotional regulationNeurocognitive deficitsUnderlying neurobiologyMental health reportsCerebral networksOlder adultsTreatment modelTreatment interventionsDepressed eldersTreatment studiesBehavioral changesNew interventionsDepressionDeficits
2011
Mentorship for Alcohol Problems (MAP): A Peer to Peer Modular Intervention for Outpatients
Tracy K, Burton M, Miescher A, Galanter M, Babuscio T, Frankforter T, Nich C, Rounsaville B. Mentorship for Alcohol Problems (MAP): A Peer to Peer Modular Intervention for Outpatients. Alcohol And Alcoholism 2011, 47: 42-47. PMID: 22045903, PMCID: PMC3243439, DOI: 10.1093/alcalc/agr136.Peer-Reviewed Original ResearchConceptsOutpatient alcohol treatment programTreatment programSubstance useAlcohol problemsCommunity treatment programsAlcohol use disorderAlcohol treatment programsDelivery of treatmentReduction of alcoholStage IModular interventionNew interventionsPatient interestBiological measuresInterventionFocus groups
2010
Cost evaluation of evidence-based treatments.
Sindelar JL, Ball SA. Cost evaluation of evidence-based treatments. Addiction Science & Clinical Practice 2010, 5: 44-51. PMID: 22002453, PMCID: PMC3120119.Peer-Reviewed Original ResearchMultisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs?
Nunes EV, Ball S, Booth R, Brigham G, Calsyn DA, Carroll K, Feaster DJ, Hien D, Hubbard RL, Ling W, Petry NM, Rotrosen J, Selzer J, Stitzer M, Tross S, Wakim P, Winhusen T, Woody G. Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs? Journal Of Substance Use And Addiction Treatment 2010, 38: s97-s112. PMID: 20307801, PMCID: PMC2909698, DOI: 10.1016/j.jsat.2010.01.012.Peer-Reviewed Original ResearchMeSH KeywordsCommunity Health ServicesComparative Effectiveness ResearchEvidence-Based MedicineHumansInformation DisseminationNational Institute on Drug Abuse (U.S.)Randomized Controlled Trials as TopicResearch DesignSubstance Abuse Treatment CentersSubstance-Related DisordersTreatment OutcomeUnited StatesConceptsClinical Trials NetworkMultisite effectiveness trialEffectiveness trialNational Drug Abuse Treatment Clinical Trials NetworkSubstance abuseNew interventionsReal-world clinical settingNew treatment interventionsPrimary outcome paperFuture effectiveness trialHIV risk behaviorsEvidence-based treatmentsBehavioral health problemsCo-occurring problemsOutcome papersClinical trialsHIV riskTreatment interventionsHealth problemsRisk behaviorsClinical settingTrials NetworkDrug abuseTrialsSuch treatmentResearch design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations
Dworkin RH, Turk DC, Peirce-Sandner S, Baron R, Bellamy N, Burke LB, Chappell A, Chartier K, Cleeland CS, Costello A, Cowan P, Dimitrova R, Ellenberg S, Farrar JT, French JA, Gilron I, Hertz S, Jadad AR, Jay GW, Kalliomäki J, Katz NP, Kerns RD, Manning DC, McDermott MP, McGrath PJ, Narayana A, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Reeve BB, Rhodes T, Sampaio C, Simpson DM, Stauffer JW, Stucki G, Tobias J, White RE, Witter J. Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations. Pain 2010, 149: 177-193. PMID: 20207481, DOI: 10.1016/j.pain.2010.02.018.Peer-Reviewed Original ResearchConceptsChronic pain clinical trialsPain clinical trialsClinical trialsPrimary efficacy analysisChronic pain trialsDemonstration of efficacyIMMPACT recommendationsResearch design considerationsAnalgesic effectPain trialsChronic painEfficacy analysisTypes of trialsConsensus meetingTreatment groupsNew interventionsTrue lackTrialsTrial phaseEfficacyMethodological weaknessesAssay sensitivityTreatmentSubstantial variabilityParticipant selection
2003
Nicotine as a modulator of behavior: beyond the inverted U
Picciotto MR. Nicotine as a modulator of behavior: beyond the inverted U. Trends In Pharmacological Sciences 2003, 24: 493-499. PMID: 12967775, DOI: 10.1016/s0165-6147(03)00230-x.Peer-Reviewed Original ResearchConceptsNeuronal pathwaysEffects of nicotineNicotinic acetylcholine receptorsNeurotransmitter release studiesSmoking cessationNicotine reinforcementOccasional smokingKnockout mouse studiesSmoking behaviorAnimal studiesAcetylcholine receptorsDifferent subtypesMouse studiesBehavioral effectsNew interventionsNicotineElectrophysiological experimentsActivation stateRecent dataBehavioral responsesModulator of behaviorSmokingPathwaySubtypesReceptorsSafer Injection Sites in New York City: A Utilization Survey of Injection Drug Users
Broadhead R, Borch C, van Hulst Y, Farrell J, Villemez W, Altice F. Safer Injection Sites in New York City: A Utilization Survey of Injection Drug Users. Journal Of Drug Issues 2003, 33: 733-750. DOI: 10.1177/002204260303300311.Peer-Reviewed Original ResearchInjection drug usersSafe injection sitesDrug overdoseSample of IDUsDrug usersInjection siteDrug-related health problemsBlood-borne diseasesInnovative public health interventionsPublic health interventionsHarm Reduction ProjectHepatitis BDental servicesDrug treatmentPre-obtained drugsHigh riskHealth personnelHealth problemsHealth interventionsSignificant health riskSexual partnersNew York CityReferral servicesStreet outreachNew interventions
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