2021
Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty
Cabrejo R, Lacadie C, Sun A, Chuang C, Yang J, Brooks E, Beckett J, Eilbott J, Gabrick K, Steinbacher D, Duncan C, DiLuna M, Alperovich M, Pelphrey K, Ventola P, Constable T, Persing JA. Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty. Journal Of Craniofacial Surgery 2021, 32: 1721-1726. PMID: 33534301, DOI: 10.1097/scs.0000000000007505.Peer-Reviewed Original ResearchConceptsWhole-vault cranioplastySagittal craniosynostosisFunctional MRICase-control study designFunctional MRI scansControl study designAbnormal network connectionsFunctional network developmentNeurological changesIndividual patientsMRI scansFunctional brain networksCerebral networksFunctional connectivityVisual networkConnectivity changesPatientsStudy designSurgeryAdolescent controlsBrain networksCraniosynostosisWVC groupInfantsExecutive function
2017
Frontal Lobe Connectivity and Network Community Characteristics are Associated with the Outcome of Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson’s Disease
Koirala N, Fleischer V, Glaser M, Zeuner K, Deuschl G, Volkmann J, Muthuraman M, Groppa S. Frontal Lobe Connectivity and Network Community Characteristics are Associated with the Outcome of Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson’s Disease. Brain Topography 2017, 31: 311-321. PMID: 28986718, DOI: 10.1007/s10548-017-0597-4.Peer-Reviewed Original ResearchConceptsDeep brain stimulationDiffusion-weighted imagingPostoperative clinical outcomesClinical responseParkinson's diseaseSTN-DBSClinical outcomesSubthalamic nucleusBrain stimulationSubthalamic nucleus deep brain stimulationNon-motor symptomsOptimal clinical responseConnectivity profilesPre-intervention predictorsEvidence-based stateIndependent predictorsPD patientsTherapy optionsClinical effectivenessCingulate gyrusFrontal lobe connectivityCerebral regionsT MRI scannerCerebral networksPrefrontal cortexBreakdown of Thalamo-Cortical Connectivity Precedes Spike Generation in Focal Epilepsies
Chiosa V, Groppa S, Ciolac D, Koirala N, Mişina L, Winter Y, Moldovanu M, Muthuraman M, Groppa S. Breakdown of Thalamo-Cortical Connectivity Precedes Spike Generation in Focal Epilepsies. Brain Connectivity 2017, 7: 309-320. PMID: 28494616, DOI: 10.1089/brain.2017.0487.Peer-Reviewed Original ResearchConceptsFrontal lobeVentral anterior nucleusThalamo-cortical connectivityFuture therapeutic approachesSpike generationFocal epileptic seizuresMedial dorsalThalamic volumeFocal epilepsyAnterior nucleusFrontal cortexTherapeutic approachesEpileptic seizuresCerebral networksCortical integrityThalamusEEG recordingsWidespread areasDistinct patternsLobeEpileptogenesisPatientsEpilepsySeizuresCortex
2012
Neuroplasticity‐based computerized cognitive remediation for geriatric depression
Morimoto SS, Wexler BE, Alexopoulos GS. Neuroplasticity‐based computerized cognitive remediation for geriatric depression. International Journal Of Geriatric Psychiatry 2012, 27: 1239-1247. PMID: 22451346, PMCID: PMC3387346, DOI: 10.1002/gps.3776.Peer-Reviewed Original ResearchConceptsComputerized cognitive remediationCognitive remediationExecutive dysfunctionGeriatric depressionSpecific executive deficitsSpecific neurocognitive deficitsSpecific cerebral networksNovel treatment interventionsAvailable treatment studiesNovel treatment modelExecutive deficitsEmotional regulationNeurocognitive deficitsUnderlying neurobiologyMental health reportsCerebral networksOlder adultsTreatment modelTreatment interventionsDepressed eldersTreatment studiesBehavioral changesNew interventionsDepressionDeficits
2005
fMRI reveals large-scale network activation in minimally conscious patients
Schiff N, Rodriguez-Moreno D, Kamal A, Kim K, Giacino J, Plum F, Hirsch J. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005, 64: 514-523. PMID: 15699384, DOI: 10.1212/01.wnl.0000150883.10285.44.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdultAttentionAuditory CortexAwarenessCerebral HemorrhageCraniocerebral TraumaEncephalomalaciaFixation, OcularHumansLanguageMagnetic Resonance ImagingMalePersistent Vegetative StatePhysical StimulationSomatosensory CortexTemporal LobeTouchVerbal BehaviorWounds, NonpenetratingConceptsCognitive functionCortical activityLanguage-related tasksResidual cognitive functionMiddle temporal gyrusTactile stimulationMeaningless stimuliActive cortical networkConscious stateLanguage stimulationNeurobiological correlatesLanguage functionTemporal gyrusBehavioral evidenceMCS patientsCortical systemsLinguistic contentAuditory stimulationCortical networksLanguage processingCerebral networksNetwork activationCortical responsesCommunication abilityFMRI maps
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