2024
Treatment of Eating Disorders: Current Status, Challenges, and Future Directions
Grilo C. Treatment of Eating Disorders: Current Status, Challenges, and Future Directions. Annual Review Of Clinical Psychology 2024, 20: 97-123. PMID: 38211625, DOI: 10.1146/annurev-clinpsy-080822-043256.Peer-Reviewed Original ResearchAnorexia nervosaBinge-eating disorderBulimia nervosaEating DisordersAdaptive treatment designsPsychological treatmentTreatment researchNervosaTreatment designDisordersBulimiaPharmacological optionsAnorexiaEnhanced outcomesExpected final online publication dateFirst-line approachOnline publication dateMedicationFirst-lineClinical guidanceAnnual ReviewAlternative treatmentRevised estimatesPatientsTreatmentWhat Next for Eating Disorder Genetics? Replacing Myths With Facts to Sharpen Our Understanding
Huckins L, Signer R, Johnson J, Wu Y, Mitchell K, Bulik C. What Next for Eating Disorder Genetics? Replacing Myths With Facts to Sharpen Our Understanding. FOCUS The Journal Of Lifelong Learning In Psychiatry 2024, 22: 418-429. PMID: 38988461, PMCID: PMC11231467, DOI: 10.1176/appi.focus.24022014.Peer-Reviewed Original ResearchEnhancing Adherence with Children and Families in the Treatment of Avoidant/Restrictive Food Intake Disorder
Salvatore Farkas L, Ashurova M, Hochman A, Dave S, Shimshoni Y. Enhancing Adherence with Children and Families in the Treatment of Avoidant/Restrictive Food Intake Disorder. 2024, 83-94. DOI: 10.1007/978-3-031-58141-0_6.Peer-Reviewed Original ResearchAvoidant/restrictive food intake disorderTreatment of avoidant/restrictive food intake disorderFood intake disorderEnhance adherenceHealth care literacyImprove treatment adherenceCare literacyMotivational interviewingIncrease patientsFamily complianceOptimal careDistorted body imageMedical educationTreatment adherenceBulimia nervosaAnorexia nervosaTreatment planningBody imageAdherenceNervosaTreatmentDisordersCaregiversCareCommitment practicesDynamic functional connectivity in anorexia nervosa: alterations in states of low connectivity and state transitions
Boehm I, Mennigen E, Geisler D, Poller N, Gramatke K, Calhoun V, Roessner V, King J, Ehrlich S. Dynamic functional connectivity in anorexia nervosa: alterations in states of low connectivity and state transitions. Journal Of Child Psychology And Psychiatry 2024, 65: 1299-1310. PMID: 38480007, DOI: 10.1111/jcpp.13970.Peer-Reviewed Original ResearchConceptsAnorexia nervosaFunctional connectivityResting state functional connectivityResting-state functional MRI dataInternalizing mental disordersAssociated with preoccupationOnset of anorexia nervosaFunctional MRI dataFemale healthy controlsHealthy controlsDynamic functional connectivityDynamics of functional connectivityTemporal dynamics of functional connectivityFunctional connectivity statesMental disordersStatic analytical approachesGroup differencesNervosaFractional timeMRI dataAdolescentsConnectivity statesFemale patientsClinical featuresTemporal dynamicsChapter 21 Gamma Knife for psychiatric indications
Lopes A, de Arruda I, Batistuzzo M, Gorgulho A, de Salles A, Miguel E. Chapter 21 Gamma Knife for psychiatric indications. 2024, 495-517. DOI: 10.1016/b978-0-443-18496-3.00021-5.Peer-Reviewed Original ResearchAnorexia nervosaObsessive-compulsive disorder patientsTreatment of psychiatric disordersAnterior limb of internal capsuleObsessive-compulsive disorderVentral anterior limbGamma KnifeGK radiosurgeryMajor depressionDisorder patientsPsychiatric disordersPsychiatric indicationsNervosaDepressionInternal capsuleSurgical modalitiesAdverse eventsDisordersAnorexiaRadiosurgeryWeight gainManiaPsychiatryBrain cystsComplications
2023
Distinguishing probable atypical anorexia nervosa from weight loss alone in a national sample of U.S. Military Veterans: Disentangling the roles of weight suppression and cognitive concerns
Neff K, Buta E, Fenn L, Ramsey C, Snow J, Haskell S, Masheb R. Distinguishing probable atypical anorexia nervosa from weight loss alone in a national sample of U.S. Military Veterans: Disentangling the roles of weight suppression and cognitive concerns. International Journal Of Eating Disorders 2023, 57: 827-838. PMID: 38129986, DOI: 10.1002/eat.24116.Peer-Reviewed Original ResearchAtypical anorexia nervosaAtypical ANWeight suppressionAnorexia nervosaClinical entityWeight lossControl groupDietary restraintMental healthDistinct clinical entityPoor mental healthOnly groupU.S. military veteransClinical significanceHigh riskVeteran populationSecondary analysisWeight gainSpecialized interventionsMilitary veteransNervosaDisordersVeteransNational studyPathology
2022
Food addiction, orthorexia nervosa and dietary diversity among Bangladeshi university students: a large online survey during the COVID-19 pandemic
Sultana M, Islam M, Sayeed A, Koly K, Baker K, Hossain R, Ahmed S, Ferdous M, Mubarak M, Potenza M, Sikder M. Food addiction, orthorexia nervosa and dietary diversity among Bangladeshi university students: a large online survey during the COVID-19 pandemic. Journal Of Eating Disorders 2022, 10: 163. PMID: 36376901, PMCID: PMC9662779, DOI: 10.1186/s40337-022-00680-0.Peer-Reviewed Original ResearchFood addictionOrthorexia nervosaDietary diversityPrevalence of ONDark green leafy vegetablesYale Food Addiction ScaleMultivariable linear regressionCOVID-19 pandemicLow dietary diversityGreen leafy vegetablesHealthy dietOrgan meatsDD scoresBangladeshi university studentsAppropriate interventionsOrganization guidelinesConclusionsThe findingsOnline surveyFood rulesNervosaGuilty feelingsCurrent studyLarge online surveyAddictionFitness goals
2021
Preoccupation in bulimia nervosa, binge‐eating disorder, anorexia nervosa, and higher weight
Lydecker JA, Simpson L, Smith SR, White MA, Grilo CM. Preoccupation in bulimia nervosa, binge‐eating disorder, anorexia nervosa, and higher weight. International Journal Of Eating Disorders 2021, 55: 76-84. PMID: 34713460, PMCID: PMC8963447, DOI: 10.1002/eat.23630.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyBinge-eating disorderShape/weightStudy groupBulimia nervosaAnorexia nervosaFood/eatingDisorder treatment outcomesEating-disorder featuresCognitive behavioral therapyHigher body weightFood/Treatment outcomesBody weightHW groupWeb-based surveyFormal diagnosisOvert behavioral featuresNervosaDepressionDisordersSignificant differencesWeight preoccupationPsychopathologyEatingAtypical Anorexia Nervosa, not so atypical after all: Prevalence, correlates, and clinical severity among United States military Veterans
Masheb RM, Ramsey CM, Marsh AG, Snow JL, Brandt CA, Haskell SG. Atypical Anorexia Nervosa, not so atypical after all: Prevalence, correlates, and clinical severity among United States military Veterans. Eating Behaviors 2021, 41: 101496. PMID: 33711788, DOI: 10.1016/j.eatbeh.2021.101496.Peer-Reviewed Original ResearchConceptsAtypical anorexia nervosaBinge Eating DisorderAnorexia nervosaBulimia nervosaMental healthUnited States military veteransSample of veteransDSM-5AAN groupAverage BMISevere underweightMean ageClinical severitySignificant diagnosisMultivariate analysisWorse functioningPast monthDietary restraintDisorder diagnosisDisorder groupNervosaEra veteransDisordersEating DisordersDiagnosis
2019
Associations between physical activity and eating‐disorder psychopathology among individuals categorised with binge‐eating disorder and bulimia nervosa
Kerrigan SG, Lydecker JA, Grilo CM. Associations between physical activity and eating‐disorder psychopathology among individuals categorised with binge‐eating disorder and bulimia nervosa. International Journal Of Clinical Practice 2019, 73: e13401. PMID: 31397950, PMCID: PMC7112656, DOI: 10.1111/ijcp.13401.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCompensatory physical activityPhysical activityEating-disorder psychopathologyBinge-eating episodesBulimia nervosaShape/weightEating-disorder featuresEating Disorder PsychopathologyHealth behaviorsCore featuresPhysical healthPotential roleDisordersGreater frequencyPsychopathologyAssociationNervosaPresent studyLower overvaluationEpisodesIndividualsMechanical TurkLower dissatisfactionOnline recruitment platformsGenome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Watson H, Yilmaz Z, Thornton L, Hübel C, Coleman J, Gaspar H, Bryois J, Hinney A, Leppä V, Mattheisen M, Medland S, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe K, Purves K, Adan R, Alfredsson L, Ando T, Andreassen O, Baker J, Berrettini W, Boehm I, Boni C, Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone R, Courtet P, Crow S, Crowley J, Danner U, Davis O, de Zwaan M, Dedoussis G, Degortes D, DeSocio J, Dick D, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan L, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter M, Fischer K, Föcker M, Foretova L, Forstner A, Forzan M, Franklin C, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder S, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins L, Hudson J, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas M, Kennedy J, Keski-Rahkonen A, Kiezebrink K, Kim Y, Klareskog L, Klump K, Knudsen G, La Via M, Le Hellard S, Levitan R, Li D, Lilenfeld L, Lin B, Lissowska J, Luykx J, Magistretti P, Maj M, Mannik K, Marsal S, Marshall C, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone A, Monteleone P, Munn-Chernoff M, Nacmias B, Navratilova M, Ntalla I, O’Toole J, Ophoff R, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer S, Schmidt U, Schork N, Schosser A, Seitz J, Slachtova L, Slagboom P, Slof-Op ‘t Landt M, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz J, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg A, van Furth E, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen A, Boden J, Brandt H, Crawford S, Halmi K, Horwood L, Johnson C, Kaplan A, Kaye W, Mitchell J, Olsen C, Pearson J, Pedersen N, Strober M, Werge T, Whiteman D, Woodside D, Stuber G, Gordon S, Grove J, Henders A, Juréus A, Kirk K, Larsen J, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery G, Wade T, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin N, Mortensen P, Sullivan P, Breen G, Bulik C. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics 2019, 51: 1207-1214. PMID: 31308545, PMCID: PMC6779477, DOI: 10.1038/s41588-019-0439-2.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesAssociation studiesTwin-based heritability estimatesEating Disorders Working GroupPsychiatric Genomics ConsortiumAnorexia nervosaBody-mass indexSignificant lociGenetic architectureRisk lociGenetics InitiativeGenomics ConsortiumLow body-mass indexMetabo-psychiatric disorderGenetic correlationsMetabolic componentsLociCases of anorexia nervosaPhysical activityAnthropometric traitsPsychiatric disordersHeritability estimatesAnorexia Nervosa Genetics InitiativeNervosaImprove outcomesToward an understanding of the distinctiveness of body-image constructs in persons categorized with overweight/obesity, bulimia nervosa, and binge-eating disorder
Grilo CM, Ivezaj V, Lydecker JA, White MA. Toward an understanding of the distinctiveness of body-image constructs in persons categorized with overweight/obesity, bulimia nervosa, and binge-eating disorder. Journal Of Psychosomatic Research 2019, 126: 109757. PMID: 31522010, PMCID: PMC6842703, DOI: 10.1016/j.jpsychores.2019.109757.Peer-Reviewed Original ResearchConceptsBinge-eating disorderOverweight/obesityStudy groupBulimia nervosaClinical measuresWeight/shapeWeight disordersEating-disorder psychopathologyBody image disturbanceStrength of associationClinical manifestationsObesityWeight gainCommunity volunteersDisordersBody image constructsNervosaDepressionTreatment formulationGroupWeighty decisions: How symptom severity and weight impact perceptions of bulimia nervosa
Galbraith K, Elmquist J, White MA, Grilo CM, Lydecker JA. Weighty decisions: How symptom severity and weight impact perceptions of bulimia nervosa. International Journal Of Eating Disorders 2019, 52: 1035-1041. PMID: 31240769, PMCID: PMC6779161, DOI: 10.1002/eat.23125.Peer-Reviewed Original ResearchConceptsBulimia nervosaSymptom frequencySerious mental health concernsMental health concernsPatient weightWeight statusMental illnessSymptom severityOverweightYoung womenHealth concernWeight stigmaSignificant differencesPatientsNervosaCurrent studyParticipantsVariables of interestIllnessNegative attitudesSeverityWomen
2017
Screen for Disordered Eating: Improving the accuracy of eating disorder screening in primary care
Maguen S, Hebenstreit C, Li Y, Dinh JV, Donalson R, Dalton S, Rubin E, Masheb R. Screen for Disordered Eating: Improving the accuracy of eating disorder screening in primary care. General Hospital Psychiatry 2017, 50: 20-25. PMID: 28987918, DOI: 10.1016/j.genhosppsych.2017.09.004.Peer-Reviewed Original ResearchConceptsBinge Eating DisorderPrimary careBulimia nervosaAnorexia nervosaDisorder ScreenPrimary care settingEating DisordersCross-sectional surveyEating Disorder Examination QuestionnaireEating Disorder ScreenCare settingsPrevalence ratesDisorder Examination QuestionnaireCases of BNDisordered EatingDiscriminative accuracyDisordersCareTrue casesExamination QuestionnaireFirst screenNervosaGood specificityEatingSCOFF
2015
Smoking status and psychosocial factors in binge eating disorder and bulimia nervosa
Chao AM, White MA, Grilo CM. Smoking status and psychosocial factors in binge eating disorder and bulimia nervosa. Eating Behaviors 2015, 21: 54-58. PMID: 26741260, PMCID: PMC4851572, DOI: 10.1016/j.eatbeh.2015.12.011.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyDepressive symptomsBulimia nervosaBeck Depression InventoryCurrent smokersSmoking historyEating Disorder Examination QuestionnaireSmoking statusCigarette smokingDisorder Examination QuestionnairePsychosocial factorsAdult volunteersDepression InventorySymptomsBattery of questionnairesDisorder psychopathologyBN groupNon-clinical groupCommunity volunteersExamination QuestionnaireSmokersSignificant differencesBingeNervosaVolunteers
2014
Factor structure and construct validity of the eating disorder examination‐questionnaire in college students: Further support for a modified brief version
Grilo CM, Reas DL, Hopwood CJ, Crosby RD. Factor structure and construct validity of the eating disorder examination‐questionnaire in college students: Further support for a modified brief version. International Journal Of Eating Disorders 2014, 48: 284-289. PMID: 25346071, PMCID: PMC4374034, DOI: 10.1002/eat.22358.Peer-Reviewed Original ResearchConceptsEating Disorder Examination QuestionnaireObese sampleYoung adultsEating-disorder psychopathologySample of personsOverweight statusSeven-itemStudy groupDisorder Examination QuestionnaireBulimia nervosaAnorexia nervosaThree-factor structureDietary restraintBody dissatisfactionConfirmatory factor analysisShape/weight overvaluationExamination QuestionnaireNonclinical groupNervosaMinireview: Metabolism of Female Reproduction: Regulatory Mechanisms and Clinical Implications
Seli E, Babayev E, Collins SC, Nemeth G, Horvath TL. Minireview: Metabolism of Female Reproduction: Regulatory Mechanisms and Clinical Implications. Endocrinology 2014, 28: 790-804. PMID: 24678733, PMCID: PMC4042071, DOI: 10.1210/me.2013-1413.Peer-Reviewed Original ResearchConceptsFemale reproductionPeripheral availabilityMetabolic disturbancesMetabolic hormonesAnorexia nervosaClinical implicationsMetabolic determinantsHuman reproductionEnergy metabolismFemale fertilityMetabolic stateMetabolismCentral processesMellitusObesityHypothalamusRegulatory mechanismsInfertilityHormoneNervosaNeuroimaging of Eating Disorders, Substance Use Disorders, and Addictions: Overlapping and Unique Systems
Gearhardt A, Boswell R, Potenza M. Neuroimaging of Eating Disorders, Substance Use Disorders, and Addictions: Overlapping and Unique Systems. 2014, 71-89. DOI: 10.1007/978-3-642-45378-6_4.Peer-Reviewed Original ResearchAddictive disordersMemory/learningDomains of impairmentBinge-eating disorderExecutive controlNeural commonalitiesEmotional reactivityInteroceptive awarenessSubstance use disordersEating DisordersBulimia nervosaDimensional approachAnorexia nervosaUse disordersFuture researchDevelopment of treatmentsNervosaDisordersRewardFunctioningMotivationAddictionConceptualizationLearningImpairment
2012
Enhanced cognitive behaviour therapy for adults with anorexia nervosa: A UK–Italy study
Fairburn CG, Cooper Z, Doll HA, O'Connor ME, Palmer RL, Grave R. Enhanced cognitive behaviour therapy for adults with anorexia nervosa: A UK–Italy study. Behaviour Research And Therapy 2012, 51: r2-r8. PMID: 23084515, PMCID: PMC3662032, DOI: 10.1016/j.brat.2012.09.010.Peer-Reviewed Original ResearchConceptsAnorexia nervosaCognitive behavior therapyLong-term outcomesBehavior therapySessions of CBTUse of CBTAdult patientsOutpatient treatmentConcurrent treatmentConsecutive referralsBulimia nervosaNew treatmentsFurther evaluationPatientsAdditional treatmentNervosaTreatmentTherapyCBTDisorder featuresStrong preliminary supportTrialsPreliminary supportPresent studyRobust evidenceBulimia nervosa
Fairburn C, Cooper Z, Murphy R. Bulimia nervosa. 2012, 801-811. DOI: 10.1093/med/9780199696758.003.0103.Peer-Reviewed Original Research
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