2021
Delirium
Munoz-Acuna R, O'Gara B. Delirium. 2021, 205-210. DOI: 10.1201/9781003042136-35.Peer-Reviewed Original ResearchIntensive care unitNewer atypical antipsychotic agentsLong-term cognitive functionIncidence of deliriumMechanical ventilation timeNumerous pharmacological strategiesUnderlying medical disorderAtypical antipsychotic agentsDelirium preventionICU lengthCare unitMechanical ventilationVentilation timeClinical trialsPharmacological strategiesSimilar efficacyAntipsychotic agentsMedical disordersDeliriumBehavioral disturbancesSide effectsMental disordersCognitive functionStatistical ManualExcess costsDepression and anxiety symptoms are related to pain and frailty but not cognition or delirium in older surgical patients
Wang S, Cardieri B, Lin H, Liu X, Sano M, Deiner S. Depression and anxiety symptoms are related to pain and frailty but not cognition or delirium in older surgical patients. Brain And Behavior 2021, 11: e02164. PMID: 33949810, PMCID: PMC8213643, DOI: 10.1002/brb3.2164.Peer-Reviewed Original ResearchConceptsAnxiety symptomsEarly cognitive declinePostoperative cognitive declineHospital Anxiety and Depression ScaleCognitive declineDepressive symptomsPreoperative depressionOlder surgical patientsSurgical patientsAssociated with early cognitive declineSymptoms of depressionOlder adultsSignificant depressive symptomsAnxiety and Depression ScaleAssociated with postoperative cognitive declineCohort study of patientsPreoperative depressive symptomsPsychiatric diagnosisElective noncardiac surgeryCognitive dysfunctionStudy of patientsCommunity dwelling older adultsPostoperative cognitive dysfunctionAnxietyIncidence of delirium
2015
Acetylcholinesterase Inhibitors for Delirium in Older Adults
Tampi RR, Tampi DJ, Ghori AK. Acetylcholinesterase Inhibitors for Delirium in Older Adults. American Journal Of Alzheimer's Disease & Other Dementias® 2015, 31: 305-310. PMID: 26646113, PMCID: PMC10852606, DOI: 10.1177/1533317515619034.Peer-Reviewed Original ResearchConceptsManagement of deliriumActive drug groupOlder adultsHospital stayAcetylcholinesterase inhibitorsDrug groupsIncidence of deliriumCochrane Collaboration databasesPlacebo groupDeliriumCurrent evidenceMortality rateSystematic reviewLiterature searchAdditional studiesStatistical significanceLonger durationAdultsLonger lengthRCTsHaloperidolStayInhibitorsPreventionBibliographic databases
2013
Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction
Radtke F, Franck M, Lendner J, Krüger S, Wernecke K, Spies C. Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. British Journal Of Anaesthesia 2013, 110: i98-i105. PMID: 23539235, DOI: 10.1093/bja/aet055.Peer-Reviewed Original ResearchConceptsPostoperative deliriumPostoperative cognitive dysfunctionBispectral index monitoringBispectral indexHigh-risk surgical patientsRate of postoperative deliriumAssociated with poor outcomesIncidence of postoperative cognitive dysfunctionIncidence of postoperative deliriumCognitive dysfunctionIncidence of deliriumLow BIS valuesFrequent complicationIntraoperative neuromonitoringElderly patientsPoor outcomeSurgical patientsRandomized trialsGeneral anesthesiaMultivariate analysisPatientsPrecipitating factorsDelirium incidenceAnesthesiaConsecutive sample
1992
Risk Factors for Delirium in Hospitalized Elderly
Schor J, Levkoff S, Lipsitz L, Reilly C, Cleary P, Rowe J, Evans D. Risk Factors for Delirium in Hospitalized Elderly. JAMA 1992, 267: 827-831. PMID: 1732655, DOI: 10.1001/jama.1992.03480060073033.Peer-Reviewed Original ResearchConceptsPrior cognitive impairmentRisk factorsOdds ratioCognitive impairmentIncidence of deliriumDetection of deliriumIndependent risk factorTertiary care hospitalUse of neurolepticsCohort analytic studyRisk factor dataPresence of infectionAcute care hospitalsPatients' medical recordsYears of ageStepwise logistic regressionHospital deliriumAnticholinergic useElderly patientsMedication groupCare hospitalHospitalized patientsNeuroleptic useSurgical wardsNarcotic use
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