2025
Body mass index and benign prostatic hyperplasia correlate with urinary microbiome diversity and lower urinary tract symptoms in men
Bowie K, Garzotto M, Orwoll E, Karstens L. Body mass index and benign prostatic hyperplasia correlate with urinary microbiome diversity and lower urinary tract symptoms in men. Communications Medicine 2025, 5: 159. PMID: 40328908, PMCID: PMC12056106, DOI: 10.1038/s43856-025-00866-y.Peer-Reviewed Original ResearchLower urinary tract symptomsBenign prostatic hyperplasiaUrinary tract symptomsBody mass indexUrinary microbiomeProstatic hyperplasiaMass indexAssociated with lower urinary tract symptomsLower urinary tractAbsence of infectionCohort of menOsteoporotic fracturesUrinary tractClinical characteristicsSignificant associationBackgroundSeveral studiesUrine samplesHyperplasiaSymptomsStudy designIllumina MiSeqRRNA geneAlpha diversityMenMicrobiome diversity
2024
Impact of Latino ethnicity on the gut microbiome composition of patients with metastatic renal cell cancer (mRCC).
Barragán Carrillo R, Dizman N, Ebrahimi H, Meza L, Bergerot P, Dorff T, Hsu J, Zengin Z, Salgia N, Chehrazi-Raffle A, Tripathi A, Castro D, Mercier B, Caporaso G, Lee K, Pal S. Impact of Latino ethnicity on the gut microbiome composition of patients with metastatic renal cell cancer (mRCC). Journal Of Clinical Oncology 2024, 42: 4521-4521. DOI: 10.1200/jco.2024.42.16_suppl.4521.Peer-Reviewed Original ResearchMetastatic renal cell cancerImmune checkpoint inhibitionGut microbiome compositionBeta diversityBacterial speciesANCOM-BCAbundance of bacterial speciesWhole metagenome sequencingF/B ratioRatio of Firmicutes/BacteroidetesStool specimensShannon diversity indexR. inulinivoransE. rectaleRenal cell cancerTaxonomic profilesMetagenomic sequencingAlpha diversityGut microbiotaGut microbiomeMicrobiome compositionBray-CurtisDiversity indexComposition of patientsGut dysbiosis
2023
Exploring the Plasticity of Diet on Gut Microbiota and Its Correlation with Gut Health
Yao S, Zhao Y, Chen H, Sun R, Chen L, Huang J, Yu Z, Chen S. Exploring the Plasticity of Diet on Gut Microbiota and Its Correlation with Gut Health. Nutrients 2023, 15: 3460. PMID: 37571397, PMCID: PMC10420685, DOI: 10.3390/nu15153460.Peer-Reviewed Original ResearchConceptsGut microbiotaGut healthComposition of gut microbiotaGut microbiota of miceProtecting gut healthRRNA gene sequencesMicrobiota of miceGut microbiota changesGene sequencesAlpha diversityHigh fiber dietMicrobiota changesPathogenic bacteriaMicrobiotaGutGenusHigh-protein dietSwitching dietsDietary impactExperimental timeframeBacteriaProbioticsHigh-protein diet groupSequenceAIN-93G diet
2021
The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer
Wang Z, Xiao R, Huang J, Qin X, Hu D, Guo E, Liu C, Lu F, You L, Sun C, Chen G. The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer. Microbial Ecology 2021, 84: 302-313. PMID: 34405250, DOI: 10.1007/s00248-021-01800-0.Peer-Reviewed Original ResearchConceptsLocally advanced cervical cancerLocally advanced cervical cancer patientsPlatinum-based chemotherapy responseAdvanced cervical cancerCervical cancerChemotherapy responseAlpha diversityVaginal microbiotaVaginal samplesCC patientsVaginal microbiomeHealthy controlsPredicting neoadjuvant chemotherapy responsePlatinum-resistant patientsNeoadjuvant chemotherapy responseAssociated with platinum-based chemotherapy responseCervical cancer patientsVaginal microbiota diversityNeoadjuvant chemotherapyHPV infectionBeta diversityBacteroides genusChemotherapy effectCancer patientsBacteroides abundanceAltered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components
Barandouzi Z, Lee J, Maas K, Starkweather A, Cong X. Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components. Journal Of Personalized Medicine 2021, 11: 35. PMID: 33429936, PMCID: PMC7827153, DOI: 10.3390/jpm11010035.Peer-Reviewed Original ResearchAlpha diversity indicesGut microbiotaIrritable bowel syndromeDiversity indexHealthy controlsHighest alpha-diversity indicesAlterations of gut microbiota compositionGut microbiota patternHigher alpha diversityGut microbiota compositionGut microbiota alterationsAltered gut microbiotaGut microbiome patternsCaffeine consumptionBowel syndromePathophysiology of irritable bowel syndromeIllumina sequencingFood frequency questionnaireAlpha diversityIrritable bowel syndrome groupIrritable bowel syndrome patientsMicrobial diversityMicrobiota compositionMicrobiota alterationsMicrobiota patterns
2016
Gut Microbiome Developmental Patterns in Early Life of Preterm Infants: Impacts of Feeding and Gender
Cong X, Xu W, Janton S, Henderson W, Matson A, McGrath J, Maas K, Graf J. Gut Microbiome Developmental Patterns in Early Life of Preterm Infants: Impacts of Feeding and Gender. PLOS ONE 2016, 11: e0152751. PMID: 27111847, PMCID: PMC4844123, DOI: 10.1371/journal.pone.0152751.Peer-Reviewed Original ResearchConceptsOperational taxonomic unitsGut microbiomeA-diversityGut microbiotaNeonatal intensive care unitPreterm infantsPatterns of gut microbiomeDiversity of gut microbiomeRRNA gene regionInfant gut microbiomeFeeding typeAbundance of EnterobacterialesGut microbiome patternsTaxonomic unitsAbundant phylumGene regionTotal readsAlpha diversityQIIME softwareV4 regionBacterial compositionDevelopmental patternsEarly lifeInfant's postnatal ageMicrobiome patterns
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